相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Discovery of autism/intellectual disability somatic mutations in Alzheimer's brains: mutated ADNP cytoskeletal impairments and repair as a case study
Yanina Ivashko-Pachima et al.
MOLECULAR PSYCHIATRY (2021)
MicroRNA-298 reduces levels of human amyloid-β precursor protein (APP), β-site APP-converting enzyme 1 (BACE1) and specific tau protein moieties
Nipun Chopra et al.
MOLECULAR PSYCHIATRY (2021)
Oxidative Damage and Antioxidant Response in Frontal Cortex of Demented and Nondemented Individuals with Alzheimer's Neuropathology
Anna Fracassi et al.
JOURNAL OF NEUROSCIENCE (2021)
The STRING database in 2021: customizable protein-protein networks, and functional characterization of user-uploaded gene/measurement sets
Damian Szklarczyk et al.
NUCLEIC ACIDS RESEARCH (2021)
THE COMPLEXITY OF ALZHEIMER'SDISEASE: AN EVOLVING PUZZLE
Camilla Ferrari et al.
PHYSIOLOGICAL REVIEWS (2021)
Promotive role of microRNA-150 in hippocampal neurons apoptosis in vascular dementia model rats
Chengqun Wei et al.
MOLECULAR MEDICINE REPORTS (2021)
Prediction of differentially expressed microRNAs in blood as potential biomarkers for Alzheimer's disease by meta-analysis and adaptive boosting ensemble learning
Sze Chung Yuen et al.
ALZHEIMERS RESEARCH & THERAPY (2021)
A novel missense variant in CUL3 shows altered binding ability to BTB-adaptor proteins leading to diverse phenotypes of CUL3-related disorders
Kohji Kato et al.
JOURNAL OF HUMAN GENETICS (2021)
Amyloid-beta accumulation cycle as a prevention and/or therapy target for Alzheimer's disease
Chinthalapally V. Rao et al.
AGING CELL (2020)
Network Medicine Approach for Analysis of Alzheimer's Disease Gene Expression Data
David Cohen et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
MicroRNA-425-5p promotes tau phosphorylation and cell apoptosis in Alzheimer's disease by targeting heat shock protein B8
Jiao Yuan et al.
JOURNAL OF NEURAL TRANSMISSION (2020)
Selected microRNAs Increase Synaptic Resilience to the Damaging Binding of the Alzheimer's Disease Amyloid Beta Oligomers
Olga Zolochevska et al.
MOLECULAR NEUROBIOLOGY (2020)
mTOR at the nexus of nutrition, growth, ageing and disease
Grace Y. Liu et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2020)
Nilotinib Effects on Safety, Tolerability, and Biomarkers in Alzheimer's Disease
Raymond S. Turner et al.
ANNALS OF NEUROLOGY (2020)
A Positive Feedback Loop of Hippo- and c-Jun-Amino-Terminal Kinase Signaling Pathways Regulates Amyloid-Beta-Mediated Neurodegeneration
Madison Irwin et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)
Brain Transcriptome Analysis Links Deficiencies of Stress-Responsive Proteins to the Pathomechanism of Kii ALS/PDC
Satoru Morimoto et al.
ANTIOXIDANTS (2020)
Alzheimer's Patient Microglia Exhibit Enhanced Aging and Unique Transcriptional Activation
Karpagam Srinivasan et al.
CELL REPORTS (2020)
Genome-wide profiling and predicted significance of post-mortem brain microRNA in Alzheimer's disease
Adriane D. Henriques et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2020)
An integrated multi-omics approach identifies epigenetic alterations associated with Alzheimer's disease
Raffaella Nativio et al.
NATURE GENETICS (2020)
Repurposed agents in the Alzheimer's disease drug development pipeline
Justin Bauzon et al.
ALZHEIMERS RESEARCH & THERAPY (2020)
Exploring the role of RALYL in Alzheimer's disease reserve by network-based approaches
Yixuan Zhang et al.
ALZHEIMERS RESEARCH & THERAPY (2020)
Transcriptomic analysis of probable asymptomatic and symptomatic alzheimer brains
Hamel Patel et al.
BRAIN BEHAVIOR AND IMMUNITY (2019)
Peri-Infarct Upregulation of the Oxytocin Receptor in Vascular Dementia
Erin C. McKay et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2019)
Intrahippocampal miR-342-3p inhibition reduces β-amyloid plaques and ameliorates learning and memory in Alzheimer's disease
Yin Fu et al.
METABOLIC BRAIN DISEASE (2019)
Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer's disease model
Peisu Zhang et al.
NATURE NEUROSCIENCE (2019)
A multiomic approach to characterize the temporal sequence in Alzheimer's disease-related pathology
Mikael Marttinen et al.
NEUROBIOLOGY OF DISEASE (2019)
Altered microRNAs related to synaptic function as potential plasma biomarkers for Alzheimer's disease
Dolores Siedlecki-Wullich et al.
ALZHEIMERS RESEARCH & THERAPY (2019)
Nilotinib interferes with cell cycle, ABC transporters and JAK-STAT signaling pathway in CD34+/lin- cells of patients with chronic phase chronic myeloid leukemia after 12 months of treatment
Alessandra Trojani et al.
PLOS ONE (2019)
Effect of AZD0530 on Cerebral Metabolic Decline in Alzheimer Disease A Randomized Clinical Trial
Christopher H. van Dyck et al.
JAMA NEUROLOGY (2019)
Differential expression of microRNAs in Alzheimer's disease brain, blood, and cerebrospinal fluid
Petros Takousis et al.
ALZHEIMERS & DEMENTIA (2019)
Blood circulating miRNAs as biomarkers of Alzheimer's disease: a systematic review and meta-analysis
Ya-Heng Zhang et al.
BIOMARKERS IN MEDICINE (2019)
Targeting Autophagy for the Treatment of Alzheimer's Disease: Challenges and Opportunities
Jie Liu et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2019)
Transcriptome Changes in the Alzheimer's Disease Middle Temporal Gyrus: Importance of RNA Metabolism and Mitochondria-Associated Membrane Genes
Ignazio S. Piras et al.
JOURNAL OF ALZHEIMERS DISEASE (2019)
Alzheimer's disease-associated (hydroxy)methylomic changes in the brain and blood
Roy Lardenoije et al.
CLINICAL EPIGENETICS (2019)
miR-212 and miR-132 Are Downregulated in Neurally Derived Plasma Exosomes of Alzheimer's Patients
Diana J. Cha et al.
FRONTIERS IN NEUROSCIENCE (2019)
Aberrant Neuronal Cell Cycle Re-Entry: The Pathological Confluence of Alzheimer's Disease and Brain Insulin Resistance, and Its Relation to Cancer
Mehmet Murat Koseoglu et al.
JOURNAL OF ALZHEIMERS DISEASE (2019)
miR-219-5p inhibits tau phosphorylation by targeting TTBK1 and GSK-3 in Alzheimer's disease
Jing Li et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2019)
The BioGRID interaction database: 2019 update
Rose Oughtred et al.
NUCLEIC ACIDS RESEARCH (2019)
miRBase: from microRNA sequences to function
Ana Kozomara et al.
NUCLEIC ACIDS RESEARCH (2019)
A novel mechanism of synaptic and cognitive impairments mediated via microRNA-30b in Alzheimer's disease
Yunping Song et al.
EBIOMEDICINE (2019)
Anti-inflammatory effect of afatinib (an EGFR-TKI) on OGD-induced neuroinflammation
Yen-Ju Chen et al.
SCIENTIFIC REPORTS (2019)
Mitophagy links oxidative stress conditions and neurodegenerative diseases
Ulfuara Shefa et al.
NEURAL REGENERATION RESEARCH (2019)
cAMP/PKA signaling pathway contributes to neuronal apoptosis via regulating IDE expression in a mixed model of type 2 diabetes and Alzheimer's disease
Huajie Li et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2018)
Spontaneous development of Alzheimer's disease-associated brain pathology in a Shugoshin-1 mouse cohesinopathy model
Chinthalapally V. Rao et al.
AGING CELL (2018)
N-methyl-D-aspartate receptor-mediated calcium influx connects amyloid-β oligomers to ectopic neuronal cell cycle reentry in Alzheimer's disease
Erin J. Kodis et al.
ALZHEIMERS & DEMENTIA (2018)
CEMiTool: a Bioconductor package for performing comprehensive modular co-expression analyses
Pedro S. T. Russo et al.
BMC BIOINFORMATICS (2018)
Trisomy of human chromosome 21 enhances amyloid-beta deposition independently of an extra copy of APP
Frances K. Wiseman et al.
BRAIN (2018)
Oxidative Stress and Decreased Mitochondrial Superoxide Dismutase 2 and Peroxiredoxins 1 and 4 Based Mechanism of Concurrent Activation of AMPK and mTOR in Alzheimer's Disease
Shohreh Majd et al.
CURRENT ALZHEIMER RESEARCH (2018)
The Amyloid-beta Oligomer Hypothesis: Beginning of the Third Decade
Erika N. Cline et al.
JOURNAL OF ALZHEIMERS DISEASE (2018)
The diabetes drug liraglutide reverses cognitive impairment in mice and attenuates insulin receptor and synaptic pathology in a non-human primate model of Alzheimer's disease
Andre F. Batista et al.
JOURNAL OF PATHOLOGY (2018)
Dysregulation of the epigenetic landscape of normal aging in Alzheimer's disease
Raffaella Nativio et al.
NATURE NEUROSCIENCE (2018)
Regulation of ADAM10 by miR-140-5p and potential relevance for Alzheimer's disease
Rumana Akhter et al.
NEUROBIOLOGY OF AGING (2018)
Multiscale Analysis of Independent Alzheimer's Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus
Ben Readhead et al.
NEURON (2018)
Region- and Cell-specific Aneuploidy in Brain Aging and Neurodegeneration
C. E. Shepherd et al.
NEUROSCIENCE (2018)
The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2018 update
Enis Afgan et al.
NUCLEIC ACIDS RESEARCH (2018)
Whole transcriptome profiling of Late-Onset Alzheimer's Disease patients provides insights into the molecular changes involved in the disease
Anita Annese et al.
SCIENTIFIC REPORTS (2018)
Diverse Brain Myeloid Expression Profiles Reveal Distinct Microglial Activation States and Aspects of Alzheimer's Disease Not Evident in Mouse Models
Brad A. Friedman et al.
CELL REPORTS (2018)
MicroRNA-455-3p as a Potential Biomarker for Alzheimer's Disease: An Update
Subodh Kumar et al.
FRONTIERS IN AGING NEUROSCIENCE (2018)
Autophagy and Alzheimer's Disease: From Molecular Mechanisms to Therapeutic Implications
Md. Sahab Uddin et al.
FRONTIERS IN AGING NEUROSCIENCE (2018)
Reactome graph database: Efficient access to complex pathway data
Antonio Fabregat et al.
PLOS COMPUTATIONAL BIOLOGY (2018)
The Impact of EGFR Gene Polymorphisms on the Risk of Alzheimer's Disease in a Chinese Han Population: A Case-Controlled Study
Xiuhong Chen et al.
MEDICAL SCIENCE MONITOR (2018)
Rac1 activation links tau hyperphosphorylation and Aβ dysmetabolism in Alzheimer's disease
Mirta Borin et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2018)
Critical role of mitosis in spontaneous late-onset Alzheimer's disease; from a Shugoshin 1 cohesinopathy mouse model
Chinthalapally V. Rao et al.
CELL CYCLE (2018)
A novel lysosome-to-mitochondria signaling pathway disrupted by amyloid-beta oligomers
Andres Norambuena et al.
EMBO JOURNAL (2018)
Comparative transcriptomics of choroid plexus in Alzheimer's disease, frontotemporal dementia and Huntington's disease: implications for CSF homeostasis
Edward G. Stopa et al.
FLUIDS AND BARRIERS OF THE CNS (2018)
The miR-15/107 Family of microRNA Genes Regulates CDK5R1/p35 with Implications for Alzheimer's Disease Pathogenesis
Silvia Moncini et al.
MOLECULAR NEUROBIOLOGY (2017)
KEGG: new perspectives on genomes, pathways, diseases and drugs
Minoru Kanehisa et al.
NUCLEIC ACIDS RESEARCH (2017)
MicroRNA Expression in the Locus Coeruleus, Entorhinal Cortex, and Hippocampus at Early and Middle Stages of Braak Neurofibrillary Tangle Pathology
Franc Llorens et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2017)
The miRNome of Alzheimer's disease: consistent downregulation of the miR-132/212 cluster
Sabrina Pichler et al.
NEUROBIOLOGY OF AGING (2017)
DNA damage during S-phase mediates the proliferation-quiescence decision in the subsequent G1 via p21 expression
Alexis R. Barr et al.
NATURE COMMUNICATIONS (2017)
Progressive modulation of the human olfactory bulb transcriptome during Alzheimer's disease evolution: novel insights into the olfactory signaling across proteinopathies
Mercedes Lachen-Montes et al.
ONCOTARGET (2017)
MiR-124 acts as a target for Alzheimer's disease by regulating BACE1
Fengmao An et al.
ONCOTARGET (2017)
miR-15b represses BACE1 expression in sporadic Alzheimer's disease
Guohua Gong et al.
ONCOTARGET (2017)
Serum microRNA miR-501-3p as a potential biomarker related to the progression of Alzheimer's disease
Norikazu Hara et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2017)
Regulator of Cell Cycle (RGCC) Expression During the Progression of Alzheimer's Disease
Scott E. Counts et al.
CELL TRANSPLANTATION (2017)
mTOR and neuronal cell cycle reentry: How impaired brain insulin signaling promotes Alzheimer's disease
Andres Norambuena et al.
ALZHEIMERS & DEMENTIA (2017)
Primate-specific miR-603 is implicated in the risk and pathogenesis of Alzheimer's disease
Chi Zhang et al.
AGING-US (2016)
miR-106b inhibits tau phosphorylation at Tyr18 by targeting Fyn in a model of Alzheimer's disease
Wei Liu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)
Expression of microRNA-34a in Alzheimer's disease brain targets genes linked to synaptic plasticity, energy metabolism, and resting state network activity
S. Sarkar et al.
BRAIN RESEARCH (2016)
Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation
Daniel C. Scott et al.
CELL (2016)
Targeting Ras Activity Prevented Amyloid Beta-Induced Aberrant Neuronal Cell Cycle Re-Entry and Death
M. Murat Koseoglu et al.
CURRENT ALZHEIMER RESEARCH (2016)
Erythropoietin and mTOR: A One-Two Punch for Aging-Related Disorders Accompanied by Enhanced Life Expectancy
Kenneth Maiese
CURRENT NEUROVASCULAR RESEARCH (2016)
Identification and Characterization of MCM3 as a Kelch-like ECH-associated Protein 1 (KEAP1) Substrate
Kathleen M. Mulvaney et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Integrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimer's disease
Minghui Wang et al.
GENOME MEDICINE (2016)
Regulatory consequences of neuronal ELAV-like protein binding to coding and non-coding RNAs in human brain
Claudia Scheckel et al.
ELIFE (2016)
Tau: The Center of a Signaling Nexus in Alzheimer's Disease
Shahzad S. Khan et al.
FRONTIERS IN NEUROSCIENCE (2016)
From cellular senescence to Alzheimer's disease: The role of telomere shortening
Virginia Boccardi et al.
AGEING RESEARCH REVIEWS (2015)
Opposite effects of two estrogen receptors on tau phosphorylation through disparate effects on the miR-218/PTPA pathway
Yan-Si Xiong et al.
AGING CELL (2015)
Fyn inhibition rescues established memory and synapse loss in Alzheimer mice
Adam C. Kaufman et al.
ANNALS OF NEUROLOGY (2015)
miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregation in vivo
Pascal Y. Smith et al.
HUMAN MOLECULAR GENETICS (2015)
Dysregulation of microRNA-219 promotes neurodegeneration through post-transcriptional regulation of tau
Ismael Santa-Maria et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
A mechanism for the suppression of homologous recombination in G1 cells
Alexandre Orthwein et al.
NATURE (2015)
The unravelling of the ubiquitin system
Aaron Ciechanover
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2015)
limma powers differential expression analyses for RNA-sequencing and microarray studies
Matthew E. Ritchie et al.
NUCLEIC ACIDS RESEARCH (2015)
mTOR inhibition activates overall protein degradation by the ubiquitin proteasome system as well as by autophagy
Jinghui Zhao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
A phase Ib multiple ascending dose study of the safety, tolerability, and central nervous system availability of AZD0530 (saracatinib) in Alzheimer's disease
Haakon B. Nygaard et al.
ALZHEIMERS RESEARCH & THERAPY (2015)
Calcium/calmodulin-dependent kinase II and Alzheimer's disease
Anshua Ghosh et al.
MOLECULAR BRAIN (2015)
Neuroinflammation and J2 prostaglandins: linking impairment of the ubiquitin-proteasome pathway and mitochondria to neurodegeneration
Maria E. Figueiredo-Pereira et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2015)
Evidence for a neuroprotective microRNA pathway in amnestic mild cognitive impairment
Rebecca B. Weinberg et al.
FRONTIERS IN NEUROSCIENCE (2015)
HTSeq-a Python framework to work with high-throughput sequencing data
Simon Anders et al.
BIOINFORMATICS (2015)
Transcriptomics Profiling of Alzheimer's Disease Reveal Neurovascular Defects, Altered Amyloid-beta Homeostasis, and Deregulated Expression of Long Noncoding RNAs
Marco Magistri et al.
JOURNAL OF ALZHEIMERS DISEASE (2015)
A Unified Hypothesis of Early- and Late-Onset Alzheimer's Disease Pathogenesis
Craig S. Atwood et al.
JOURNAL OF ALZHEIMERS DISEASE (2015)
A Clinical Study of Lupron Depot in the Treatment of Women with Alzheimer's Disease: Preservation of Cognitive Function in Patients Taking an Acetylcholinesterase Inhibitor and Treated with High Dose Lupron Over 48 Weeks
Richard L. Bowen et al.
JOURNAL OF ALZHEIMERS DISEASE (2015)
Altered Expression of Diabetes-Related Genes in Alzheimer's Disease Brains: The Hisayama Study
Masaaki Hokama et al.
CEREBRAL CORTEX (2014)
Receptor for AGEs (RAGE) as Mediator of NF-kB Pathway Activation in Neuroinflammation and Oxidative Stress
Julio C. Tobon-Velasco et al.
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2014)
Estrogen Receptor α Variants Affect Age at Onset of Alzheimer's Disease in a Multiethnic Female Cohort
S. C. Janicki et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2014)
MicroRNA-125b induces tau hyperphosphorylation and cognitive deficits in Alzheimer's disease
Julia Banzhaf-Strathmann et al.
EMBO JOURNAL (2014)
MicroRNA-339-5p Down-regulates Protein Expression of β-Site Amyloid Precursor Protein-Cleaving Enzyme 1 (BACE1) in Human Primary Brain Cultures and Is Reduced in Brain Tissue Specimens of Alzheimer Disease Subjects*
Justin M. Long et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Inhibition of AMP-Activated Protein Kinase Signaling Alleviates Impairments in Hippocampal Synaptic Plasticity Induced by Amyloid β
Tao Ma et al.
JOURNAL OF NEUROSCIENCE (2014)
Synaptic and Cognitive Improvements by Inhibition of 2-AG Metabolism Are through Upregulation of MicroRNA-188-3p in a Mouse Model of Alzheimer's Disease
Jian Zhang et al.
JOURNAL OF NEUROSCIENCE (2014)
Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases
Manikandan Narayanan et al.
MOLECULAR SYSTEMS BIOLOGY (2014)
MicroRNAs in Alzheimer's disease: differential expression in hippocampus and cell-free cerebrospinal fluid
Mareike Muller et al.
NEUROBIOLOGY OF AGING (2014)
Relationship between amyloid-beta and the ubiquitin-proteasome system in Alzheimer's disease
Liang Hong et al.
NEUROLOGICAL RESEARCH (2014)
The multiMiR R package and database: integration of microRNA-target interactions along with their disease and drug associations
Yuanbin Ru et al.
NUCLEIC ACIDS RESEARCH (2014)
Genes associated with the progression of neurofibrillary tangles in Alzheimer's disease
A. Miyashita et al.
TRANSLATIONAL PSYCHIATRY (2014)
Disease-specific molecular events in cortical multiple sclerosis lesions
Marie Therese Fischer et al.
BRAIN (2013)
Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer's Disease
Bin Zhang et al.
CELL (2013)
Alteration of the microRNA network during the progression of Alzheimer's disease
Pierre Lau et al.
EMBO MOLECULAR MEDICINE (2013)
De-repression of FOXO3a death axis by microRNA-132 and-212 causes neuronal apoptosis in Alzheimers disease
Hon-Kit Andus Wong et al.
HUMAN MOLECULAR GENETICS (2013)
A Study of Small RNAs from Cerebral Neocortex of Pathology-Verified Alzheimer's Disease, Dementia with Lewy Bodies, Hippocampal Sclerosis, Frontotemporal Lobar Dementia, and Non-Demented Human Controls
Sebastien S. Hebert et al.
JOURNAL OF ALZHEIMERS DISEASE (2013)
Amyloid-β signals through tau to drive ectopic neuronal cell cycle re-entry in Alzheimer's disease
Matthew E. Seward et al.
JOURNAL OF CELL SCIENCE (2013)
Regulation of the DNA Damage Response by Cyclin-Dependent Kinases
Camilla Trovesi et al.
JOURNAL OF MOLECULAR BIOLOGY (2013)
MiR-26b, Upregulated in Alzheimer's Disease, Activates Cell Cycle Entry, Tau-Phosphorylation, and Apoptosis in Postmitotic Neurons
Sabrina Absalon et al.
JOURNAL OF NEUROSCIENCE (2013)
Replication Stress and Mitotic Dysfunction in Cells Expressing Simian Virus 40 Large T Antigen
Liang Hu et al.
JOURNAL OF VIROLOGY (2013)
Count-based differential expression analysis of RNA sequencing data using R and Bioconductor
Simon Anders et al.
NATURE PROTOCOLS (2013)
A preliminary study of the whole-genome expression profile of sporadic and monogenic early-onset Alzheimer's disease
Anna Antonell et al.
NEUROBIOLOGY OF AGING (2013)
InnateDB: systems biology of innate immunity and beyond-recent updates and continuing curation
Karin Breuer et al.
NUCLEIC ACIDS RESEARCH (2013)
The PINK1-Parkin pathway promotes both mitophagy and selective respiratory chain turnover in vivo
Evelyn S. Vincow et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Genes and pathways underlying regional and cell type changes in Alzheimer's disease
Jeremy A. Miller et al.
GENOME MEDICINE (2013)
TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions
Daehwan Kim et al.
GENOME BIOLOGY (2013)
Brain site-specific proteome changes in aging-related dementia
Arulmani Manavalan et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2013)
Selection of novel reference genes for use in the human central nervous system: a BrainNet Europe Study
Pascal F. Durrenberger et al.
ACTA NEUROPATHOLOGICA (2012)
miR-206 regulates brain-derived neurotrophic factor in Alzheimer disease model
Soon-Tae Lee et al.
ANNALS OF NEUROLOGY (2012)
Bioenergetic role of mitochondrial fusion and fission
Benedikt Westermann
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2012)
mTOR Signaling in Growth Control and Disease
Mathieu Laplante et al.
CELL (2012)
Regulation of NMDA receptors by the tyrosine kinase Fyn
Catherine H. Trepanier et al.
FEBS JOURNAL (2012)
Role of estrogen receptor alpha and beta expression and signaling on cognitive function during aging
Thomas C. Foster
HIPPOCAMPUS (2012)
Highly Pathogenic Alzheimer's Disease Presenilin 1 P117R Mutation Causes a Specific Increase in p53 and p21 Protein Levels and Cell Cycle Dysregulation in Human Lymphocytes
Emilia Bialopiotrowicz et al.
JOURNAL OF ALZHEIMERS DISEASE (2012)
Global analysis of genome, transcriptome and proteome reveals the response to aneuploidy in human cells
Silvia Stingele et al.
MOLECULAR SYSTEMS BIOLOGY (2012)
Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons
Ji Won Um et al.
NATURE NEUROSCIENCE (2012)
clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters
Guangchuang Yu et al.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY (2012)
Epidermal growth factor receptor is a preferred target for treating Amyloid-β-induced memory loss
Lei Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
NEW: Network-Enabled Wisdom in Biology, Medicine, and Health Care
Eric E. Schadt et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Forkhead Homeobox Type O Transcription Factors in the Responses to Oxidative Stress
Peter Storz
ANTIOXIDANTS & REDOX SIGNALING (2011)
Short-term Hormone Therapy with Transdermal Estradiol Improves Cognition for Postmenopausal Women with Alzheimer's Disease: Results of a Randomized Controlled Trial
Whitney Wharton et al.
JOURNAL OF ALZHEIMERS DISEASE (2011)
Microarray analyses of laser-captured hippocampus reveal distinct gray and white matter signatures associated with incipient Alzheimer's disease
Eric M. Blalock et al.
JOURNAL OF CHEMICAL NEUROANATOMY (2011)
MicroRNA-137/181c Regulates Serine Palmitoyltransferase and In Turn Amyloid β, Novel Targets in Sporadic Alzheimer's Disease
Hirosha Geekiyanage et al.
JOURNAL OF NEUROSCIENCE (2011)
Mitosis-specific phosphorylation of amyloid precursor protein at Threonine 668 leads to its altered processing and association with centrosomes
Monique Judge et al.
MOLECULAR NEURODEGENERATION (2011)
Genome-wide analysis of miRNA expression reveals a potential role for miR-144 in brain aging and spinocerebellar ataxia pathogenesis
Stephan Persengiev et al.
NEUROBIOLOGY OF AGING (2011)
Neuronal differentiation by TAp73 is mediated by microRNA-34a regulation of synaptic protein targets
Massimiliano Agostini et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Ranking stability and super-stable nodes in complex networks
Gourab Ghoshal et al.
NATURE COMMUNICATIONS (2011)
Masitinib as an adjunct therapy for mild-to-moderate Alzheimer's disease: a randomised, placebo-controlled phase 2 trial
Francois Piette et al.
ALZHEIMERS RESEARCH & THERAPY (2011)
Luteinizing-hormone Releasing Hormone Therapy and the Risk of Death From Alzheimer Disease
Anthony V. D'Amico et al.
ALZHEIMER DISEASE & ASSOCIATED DISORDERS (2010)
Selective Cell Death of Hyperploid Neurons in Alzheimer's Disease
Thomas Arendt et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
Mark D. Robinson et al.
BIOINFORMATICS (2010)
Genetic ablation of Dicer in adult forebrain neurons results in abnormal tau hyperphosphorylation and neurodegeneration
Sebastien S. Hebert et al.
HUMAN MOLECULAR GENETICS (2010)
Conducting Meta-Analyses in R with the metafor Package
Wolfgang Viechtbauer
JOURNAL OF STATISTICAL SOFTWARE (2010)
A global map of human gene expression
Margus Lukk et al.
NATURE BIOTECHNOLOGY (2010)
Aberrant microRNA expression in the brains of neurodegenerative diseases: miR-29a decreased in Alzheimer disease brains targets neurone navigator 3
M. Shioya et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2010)
Joint Genome-Wide Profiling of miRNA and mRNA Expression in Alzheimer's Disease Cortex Reveals Altered miRNA Regulation
Juan Nunez-Iglesias et al.
PLOS ONE (2010)
Evidence for natural antisense transcript-mediated inhibition of microRNA function
Mohammad Ali Faghihi et al.
GENOME BIOLOGY (2010)
Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease
David J. Bonda et al.
AGING-US (2009)
The Sequence Alignment/Map format and SAMtools
Heng Li et al.
BIOINFORMATICS (2009)
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
David Moher et al.
JOURNAL OF CLINICAL EPIDEMIOLOGY (2009)
MicroRNA regulation of Alzheimer's Amyloid precursor protein expression
Sebastien S. Hebert et al.
NEUROBIOLOGY OF DISEASE (2009)
Aneuploidy in the normal, Alzheimer's disease and ataxia-telangiectasia brain: Differential expression and pathological meaning
Ivan Y. Iourov et al.
NEUROBIOLOGY OF DISEASE (2009)
Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease
Hyoung-gon Lee et al.
NEUROCHEMISTRY INTERNATIONAL (2009)
The Nun Study Clinically silent AD, neuronal hypertrophy, and linguistic skills in early life
D. Iacono et al.
NEUROLOGY (2009)
Transcriptome Analysis of Synaptoneurosomes Identifies Neuroplasticity Genes Overexpressed in Incipient Alzheimer's Disease
Celia Williams et al.
PLOS ONE (2009)
Comprehensive mRNA Expression Profiling Distinguishes Tauopathies and Identifies Shared Molecular Pathways
Iraad F. Bronner et al.
PLOS ONE (2009)
Neural cell cycle dysregulation and central nervous system diseases
Wei Wang et al.
PROGRESS IN NEUROBIOLOGY (2009)
Minimum Information About a Microarray Experiment (MIAME) - Successes, Failures, Challenges
Alvis Brazma
THESCIENTIFICWORLDJOURNAL (2009)
Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways
John P. Cogswell et al.
JOURNAL OF ALZHEIMERS DISEASE (2008)
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
Derek Narendra et al.
JOURNAL OF CELL BIOLOGY (2008)
Aβ Oligomers Induce Neuronal Cell Cycle Events in Alzheimer's Disease
Nicholas H. Varvel et al.
JOURNAL OF NEUROSCIENCE (2008)
A novel protein, luman/CREB3 recruitment factor, inhibits luman activation of the unfolded protein response (vol 28, pg 3952, 2008)
Timothy E. Audas et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/β-secretase expression
Sebastien S. Hebert et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Gene expression changes in the course of normal brain aging are sexually dimorphic
Nicole C. Berchtold et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Amyloid-β overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins
Xinglong Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Male pheromone-stimulated neurogenesis in the adult female brain: possible role in mating behavior
Gloria K. Mak et al.
NATURE NEUROSCIENCE (2007)
GEOquery: a bridge between the gene expression omnibus (GEO) and BioConductor
Davis Sean et al.
BIOINFORMATICS (2007)
Presenilin/γ-secretase-dependent processing of β-amyloid precursor protein regulates EGF receptor expression
Yun-wu Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Conditional neuronal simian virus 40 T antigen expression induces Alzheimer-like tau and amyloid pathology in mice
Kevin H. J. Park et al.
JOURNAL OF NEUROSCIENCE (2007)
Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain
Winnie S. Liang et al.
PHYSIOLOGICAL GENOMICS (2007)
Fbw7/hCDC4 dimerization regulates its substrate interactions
Markus Welcker et al.
CELL DIVISION (2007)
Alzheimer disease, the two-hit hypothesis: An update
Xiongwei Zhu et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2007)
Reduction of soluble Aβ and Tau, but not soluble Aβ alone, ameliorates cognitive decline in transgenic mice with plaques and tangles
Salvatore Oddo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Gene expression analyses reveal molecular relationships among 20 regions of the human CNS
RB Roth et al.
NEUROGENETICS (2006)
Dasatinib (BMS-354825) tyrosine kinase inhibitor suppresses invasion and induces cell cycle arrest and apoptosis of head and neck squamous cell carcinoma and non-small cell lung cancer cells
FM Johnson et al.
CLINICAL CANCER RESEARCH (2005)
Changes in estrogen receptor-α and -β in the infundibular nucleus of the human hypothalamus are related to the occurrence of Alzheimer's disease neuropathology
A Hestiantoro et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2004)
Proteasomes and their kin: Proteases in the machine age
CM Pickart et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
Incipient Alzheimer's disease: Microarray correlation analyses reveal major transcriptional and tumor suppressor responses
EM Blalock et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Age-dependent declines in proteasome activity in the heart
AL Bulteau et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2002)
Metabolic, Metallic, and Mitotic Sources of Oxidative Stress in Alzheimer Disease
Mark A. Smith et al.
ANTIOXIDANTS & REDOX SIGNALING (2000)
分享论文
