期刊
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
卷 69, 期 47, 页码 14049-14064出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.jafc.1c05274
关键词
food safety; aptamer; SERS labels; multiplex analysis; review
资金
- Foundation of China [32102088]
- Agricultural scientific and technological innovation project of Shandong Academy of Agricultural Sciences [CXGC2021B14, CXGC2021A19]
- National Pear Industry Technology System [CARS-28-24]
This review article focuses on the applications of SERS-based aptasensors in food safety, covering principles, specific applications, challenges in improving performance, and suggestions for choosing suitable sensors. The multiplex analysis and advancements in sensor design and preparation are highlighted throughout the text.
Owing to the excellent performances of high sensitivity, high specificity, on-site detection, and multiplexing capability, surface-enhanced Raman scattering (SERS)-based aptasensors have performed prosperous applications and gained impressive progress in food safety. Herein, we reviewed the SERS-based aptasensors from the principles to specific applications in food safety. First, the sensor-working principles, SERS label design and preparation are introduced. Then, the popular platforms in the aptasensors are summarized with their advantages and disadvantages, followed by their representative applications. Further, the specific applications of developing SERS-based aptasensors in food safety are systematically provided. Moreover, the multiplex analysis using SERS labels are highlighted. Finally, challenges and perspectives for improving the SERS-based aptasensor performance are also discussed, aiming to give some proposes for researchers to choose suitable SERS-based aptasensors according to specific applications.
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