4.7 Article

Linear Epitopes Play an Important Role in the Immunoglobulin G (IgG)/Immunoglobulin E (IgE)-Binding Capacity of Scy p 4

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Allergy

Are Physicochemical Properties Shaping the Allergenic Potency of Animal Allergens?

Joana Costa et al.

Summary: Physicochemical parameters play a crucial role in shaping the allergenicity of animal proteins. However, there are significant knowledge gaps in understanding protein allergenicity from both animal and plant origins, necessitating further comprehensive research and data integration in the future.

CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY (2022)

Article Agriculture, Multidisciplinary

Site-Directed Mutations of Calcium-Binding Sites Contribute to Reducing the Immunoreactivity of the EF-Hand Sarcoplasmic Calcium-Binding Protein in Scylla paramamosain

Yi-Yu Chen et al.

Summary: Site-directed mutations were utilized to reduce the immunoreactivity of sarcoplasmic calcium-binding protein (SCP) by replacing key amino acids in conformational epitopes and calcium-binding sites. The mutant SCPs effectively inhibited the binding with wild-type SCP and downregulated the expression levels of CD63 and CD203c on basophil surface, indicating impaired calcium binding ability and reduced immunoreactivities. This approach showed potential for application in reducing immunoreactivities of other shellfish allergens.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2021)

Article Chemistry, Applied

Mapping and IgE-binding capacity analysis of heat/digested stable epitopes of mud crab allergens

Meng Liu et al.

Summary: After high temperature-pressure treatment, the allergenic potential of tropomyosin and arginine kinase in mud crab was evaluated, showing higher prevalence and sensitivity to heat processing. New epitopes were identified among the 35 stable epitopes, and seven heat/digested stable peptides retained IgE-binding capacity.

FOOD CHEMISTRY (2021)

Article Agriculture, Multidisciplinary

Combination Processing Method Reduced IgE-Binding Activity of Litopenaeus vannamei by Modifying Lysine, Arginine, and Cysteine on Multiple Allergen Epitopes

Meng Liu et al.

Summary: This study investigates the low-allergenic food processing for Litopenaeus vannamei by analyzing macrostructure, digestibility, and immunoreactivity. The combination processing of Maillard reaction with high temperature-pressure significantly changes the shrimp meat's properties and reduces its IgE-binding activity. This research provides a new method to explore hypo-IgE-binding activity in food through the modification of amino acid residues in antigen epitopes.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2021)

Review Food Science & Technology

Whey allergens: Influence of nonthermal processing treatments and their detection methods

Mati Ullah Khan et al.

Summary: Whey and its components are valuable ingredients in food products, but can trigger allergic reactions. Precise analytical technologies for detecting whey allergens are crucial in food processing.

COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY (2021)

Article Biochemistry & Molecular Biology

Insight into Calcium-Binding Motifs of Intrinsically Disordered Proteins

Estella A. Newcombe et al.

Summary: Motifs within proteins help categorize their functions;Intrinsically disordered proteins (IDPs) rich in short linear motifs with various roles;Study found calcium-binding motifs in IDPs may serve various underreported structural and functional roles.

BIOMOLECULES (2021)

Article Allergy

Development of a novel Ara h 2 hypoallergen with no IgE binding or anaphylactogenic activity

Angelika Tscheppe et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2020)

Review Allergy

An update on shellfish allergy

Lydia Wong et al.

CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY (2019)

Article Agriculture, Multidisciplinary

Reducing Allergenicity to Arginine Kinase from Mud Crab Using Site-Directed Mutagenesis and Peptide Aptamers

Xue-Jiao Mei et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2019)

Article Food Science & Technology

Rational Design, Structure-Activity Relationship, and Immunogenicity of Hypoallergenic Pru p 3 Variants

Stephanie Eichhorn et al.

MOLECULAR NUTRITION & FOOD RESEARCH (2019)

Article Multidisciplinary Sciences

Rational design of a hypoallergenic Phl p 7 variant for immunotherapy of polcalcin-sensitized patients

Marianne Raith et al.

SCIENTIFIC REPORTS (2019)

Article Agriculture, Multidisciplinary

Cloning, Expression, and Epitope Identification of Myosin Light Chain 1: An Allergen in Mud Crab

Meng-Si Li et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2019)

Article Allergy

IgE-Mediated Food Allergy

Sara Anvari et al.

CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY (2019)

Review Biochemistry & Molecular Biology

Seafood allergy: A comprehensive review of fish and shellfish allergens

Thimo Ruethers et al.

MOLECULAR IMMUNOLOGY (2018)

Article Agriculture, Multidisciplinary

Cloning, Expression, and the Effects of Processing on SarcoplasmicCalcium-Binding Protein: An Important Allergen in Mud Crab

Meng-Jun Hu et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2017)

Review Allergy

Shellfish allergens: tropomyosin and beyond

M. A. Faber et al.

ALLERGY (2017)

Article Biochemistry & Molecular Biology

Epitope Mapping of Rhi o 1 and Generation of a Hypoallergenic Variant: A CANDIDATE MOLECULE FOR FUNGAL ALLERGY VACCINES

Gaurab Sircar et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2016)

Review Immunology

An Introduction to B-Cell Epitope Mapping and In Silico Epitope Prediction

Lenka Potocnakova et al.

JOURNAL OF IMMUNOLOGY RESEARCH (2016)

Review Immunology

Food allergy: immune mechanisms, diagnosis and immunotherapy

Wong Yu et al.

NATURE REVIEWS IMMUNOLOGY (2016)

Article Food Science & Technology

In vitro assessment of allergenicity features and localization of probable IgE binding regions

Ankita Mishra et al.

FOOD AND CHEMICAL TOXICOLOGY (2015)

Article Biochemistry & Molecular Biology

Mapping and characterization of antigenic epitopes of arginine kinase of Scylla paramamosain

Yang Yang et al.

MOLECULAR IMMUNOLOGY (2015)

Article Biochemistry & Molecular Biology

A folding study of Antarctic krill (Euphausia superba) alkaline phosphatase using denaturants

Zhi-Jiang Wang et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2014)

Article Biochemistry & Molecular Biology

Purification, characterization, and unfolding studies of arginine kinase from Antarctic krill

Yue-Xiu Si et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2014)

Article Agriculture, Multidisciplinary

Molecular cloning and functional expression of allergenic sarcoplasmic calcium-binding proteins from Penaeus shrimps

Hajime Mita et al.

JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE (2013)

Article Biochemistry & Molecular Biology

Structural biology of mite allergens

Yubao Cui

MOLECULAR BIOLOGY REPORTS (2013)

Article Biochemistry & Molecular Biology

Conformational epitope mapping of Pru du 6, a major allergen from almond nut

LeAnna N. Willison et al.

MOLECULAR IMMUNOLOGY (2013)

Article Allergy

Hypoallergenic Der p 1/Der p 2 combination vaccines for immunotherapy of house dust mite allergy

Kuan-Wei Chen et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2012)

Review Allergy

Shellfish allergy

A. L. Lopata et al.

CLINICAL AND EXPERIMENTAL ALLERGY (2010)

Review Allergy

The role of immunoglobulin E-binding epitopes in the characterization of food allergy

Jing Lin et al.

CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY (2009)

Article Allergy

Sarcoplasmic calcium-binding protein is an EF-hand-type protein identified as a new shrimp allergen

Rosalia Ayuso et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2009)

Review Allergy

Allergen structures and biologic functions:: The cutting edge of allergy research

Anna Pomes

CURRENT ALLERGY AND ASTHMA REPORTS (2008)

Article Allergy

Sarcoplasmic calcium-binding protein: Identification as a new allergen of the black tiger shrimp Penaeus monodon

Kazuo Shiomi et al.

INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY (2008)

Review Allergy

What makes a food protein an allergen?

GA Bannon

CURRENT ALLERGY AND ASTHMA REPORTS (2004)