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Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity
Yiqi Guo et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Activation of Autophagy by α-Herpesviruses in Myeloid Cells Is Mediated by Cytoplasmic Viral DNA through a Mechanism Dependent on Stimulator of IFN Genes
Simon B. Rasmussen et al.
JOURNAL OF IMMUNOLOGY (2011)
A role for DNA-dependent activator of interferon regulatory factor in the recognition of herpes simplex virus type 1 by glial cells
Samantha R. Furr et al.
JOURNAL OF NEUROINFLAMMATION (2011)
Reactive Astrocytes Inhibit the Survival and Differentiation of Oligodendrocyte Precursor Cells by Secreted TNF-α
Zhida Su et al.
JOURNAL OF NEUROTRAUMA (2011)
Gene expression reveals overlap between normal aging and Alzheimer's disease genes
Dimitrios Avramopoulos et al.
NEUROBIOLOGY OF AGING (2011)
Herpes Simplex Virus Dances with Amyloid Precursor Protein while Exiting the Cell
Shi-Bin Cheng et al.
PLOS ONE (2011)
Activation of PKR Causes Amyloid β-Peptide Accumulation via De-Repression of BACE1 Expression
Gerard Ill-Raga et al.
PLOS ONE (2011)
RNA Oxidation Adducts 8-OHG and 8-OHA Change with Aβ42 Levels in Late-Stage Alzheimer's Disease
Adam M. Weidner et al.
PLOS ONE (2011)
Neuropathological Alterations in Alzheimer Disease
Alberto Serrano-Pozo et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2011)
Astrocytes: biology and pathology
Michael V. Sofroniew et al.
ACTA NEUROPATHOLOGICA (2010)
Early Oligodendrocyte/Myelin Pathology in Alzheimer's Disease Mice Constitutes a Novel Therapeutic Target
Maya K. Desai et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
Chronic Cortical and Subcortical Pathology with Associated Neurological Deficits Ensuing Experimental Herpes Encephalitis
Anibal G. Armien et al.
BRAIN PATHOLOGY (2010)
Concomitant Astroglial Atrophy and Astrogliosis in a Triple Transgenic Animal Model of Alzheimer's Disease
Markel Olabarria et al.
GLIA (2010)
Human TRAF3 Adaptor Molecule Deficiency Leads to Impaired Toll-like Receptor 3 Response and Susceptibility to Herpes Simplex Encephalitis
Rebeca Perez de Diego et al.
IMMUNITY (2010)
Herpes simplex virus induces neural oxidative damage via microglial cell Toll-like receptor-2
Scott J. Schachtele et al.
JOURNAL OF NEUROINFLAMMATION (2010)
MECHANISMS OF DISEASE Alzheimer's Disease
Henry W. Querfurth et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
APP Processing Induced by Herpes Simplex Virus Type 1 (HSV-1) Yields Several APP Fragments in Human and Rat Neuronal Cells
Giovanna De Chiara et al.
PLOS ONE (2010)
Antiviral agents in Alzheimer’s disease: hope for the future?
Matthew A. Wozniak et al.
Therapeutic Advances in Neurological Disorders (2010)
Alzheimer's Disease-Specific Tau Phosphorylation is Induced by Herpes Simplex Virus Type 1
Matthew A. Wozniak et al.
JOURNAL OF ALZHEIMERS DISEASE (2009)
Microglia Mediate the Clearance of Soluble Aβ through Fluid Phase Macropinocytosis
Shweta Mandrekar et al.
JOURNAL OF NEUROSCIENCE (2009)
Herpes simplex virus type 1 DNA is located within Alzheimer's disease amyloid plaques
M. A. Wozniak et al.
JOURNAL OF PATHOLOGY (2009)
Formation and maintenance of Alzheimer's disease β-amyloid plaques in the absence of microglia
Stefan A. Grathwohl et al.
NATURE NEUROSCIENCE (2009)
Oligodendrocytes are a Novel Source of Amyloid Peptide Generation
Stephen D. Skaper et al.
NEUROCHEMICAL RESEARCH (2009)
HSV-1 infection of human brain cells induces miRNA-146a and Alzheimer-type inflammatory signaling
James M. Hill et al.
NEUROREPORT (2009)
Molecular dissection of reactive astrogliosis and glial scar formation
Michael V. Sofroniew
TRENDS IN NEUROSCIENCES (2009)
Innate and Adaptive Immune Responses to Herpes Simplex Virus
Tracy Chew et al.
VIRUSES-BASEL (2009)
Glial toll-like receptor signaling in central nervous system infection and autoimmunity
Pamela A. Carpentier et al.
BRAIN BEHAVIOR AND IMMUNITY (2008)
Hyperphosphorylation of Microtubule-Associated Protein Tau: A Promising Therapeutic Target for Alzheimer Disease
C. -X. Gong et al.
CURRENT MEDICINAL CHEMISTRY (2008)
Prolonged Microglial Cell Activation and Lymphocyte Infiltration following Experimental Herpes Encephalitis
Cristina P. Marques et al.
JOURNAL OF IMMUNOLOGY (2008)
Molecular basis for detection of invading pathogens in the brain
Jeppe Falsig et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2008)
Microglia are the major cellular source of inducible nitric oxide synthase during experimental herpes encephalitis
Cristina P. Marques et al.
JOURNAL OF NEUROVIROLOGY (2008)
Herpes simplex virus infection causes cellular β-amyloid accumulation and secretase upregulation
Matthew A. Wozniak et al.
NEUROSCIENCE LETTERS (2007)
Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimers disease
Mark A. Lovell et al.
NUCLEIC ACIDS RESEARCH (2007)
Inflammaging as a major characteristic of old people: Can it be prevented or cured?
Claudio Franceschi
NUTRITION REVIEWS (2007)
Analysis of the role of autophagy in replication of herpes simplex virus in cell culture
Diane E. Alexander et al.
JOURNAL OF VIROLOGY (2007)
Herpes simplex virus type 1 infection induces oxidative stress and the release of bioactive lipid peroxidation by-products in mouse P19N neural cell cultures
Jerry H. Kavouras et al.
JOURNAL OF NEUROVIROLOGY (2007)
TLR3 deficiency in patients with herpes simplex encephalitis
Shen-Ying Zhang et al.
SCIENCE (2007)
Toll-like receptor 2 signaling is a mediator of apoptosis in herpes simplex virus-infected microglia
Rajagopal N. Aravalli et al.
JOURNAL OF NEUROINFLAMMATION (2007)
HSV-1ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein
Anthony Orvedahl et al.
CELL HOST & MICROBE (2007)
Disseminated neonatal herpes caused by herpes simplex virus types 1 and 2
Aleksandra Knezevic et al.
EMERGING INFECTIOUS DISEASES (2007)
Differential apoptotic signaling in primary glial cells infected with herpes simplex virus 1
Rajagopal N. Aravalli et al.
JOURNAL OF NEUROVIROLOGY (2006)
Herpes simplex virus encephalitis in human UNC-93B deficiency
Armanda Casrouge et al.
SCIENCE (2006)
Neurotropism of herpes simplex virus type 1 in brain organ cultures
Efrat Braun et al.
JOURNAL OF GENERAL VIROLOGY (2006)
Microglial cells initiate vigorous yet non-protective immune responses during HSV-1 brain infection
Cristina P. Marques et al.
VIRUS RESEARCH (2006)
Innate and adaptive host response during the initial phase of herpes simplex virus encephalitis in the neonatal mouse
Guttalu K. Kumaraswamy et al.
JOURNAL OF NEUROVIROLOGY (2006)
The role of Toll-like receptors in CNS response to microbial challenge
Gregory W. Konat et al.
JOURNAL OF NEUROCHEMISTRY (2006)
Expression of nectin-1 in normal and herpes simplex virus type 1-infected murine brain
Deepak Shukla et al.
APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY (2006)
ICP0 gene expression is a herpes simplex virus type 1 apoptotic trigger
Christine M. Sanfilippo et al.
JOURNAL OF VIROLOGY (2006)
Human amyloid β-induced neuroinflammation is an early event in neurodegeneration
JM Craft et al.
GLIA (2006)
Reactive astrocytes in neural repair and protection
MV Sofroniew
NEUROSCIENTIST (2005)
High susceptibility of a human oligodendroglial cell line to herpes simplex type 1 infection
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JOURNAL OF NEUROVIROLOGY (2005)
The vomeronasal chemosensory system as a route of neuroinvasion by herpes simplex virus
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VIROLOGY (2005)
β-Amyloid-stimulated microglia induce neuron death via synergistic stimulation of tumor necrosis factor α and NMDA receptors
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JOURNAL OF NEUROSCIENCE (2005)
Productive herpes simplex virus in brain of elderly normal subjects and Alzheimer's disease patients
MA Wozniak et al.
JOURNAL OF MEDICAL VIROLOGY (2005)
The herpes simplex virus ICP0 RING finger domain inhibits IRF3 and IRF7-mediated activation of interferon-stimulated genes
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JOURNAL OF VIROLOGY (2004)
Amyloid-β peptide induces oligodendrocyte death by activating the neutral sphingomyelinase-ceramide pathway
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JOURNAL OF CELL BIOLOGY (2004)
Herpes simplex virus protein kinase US3 activates and functionally overlaps protein kinase A to block apoptosis
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Contribution of glial cells to the development of amyloid plaques in Alzheimer's disease
RG Nagele et al.
NEUROBIOLOGY OF AGING (2004)
Reversible paired helical filament-like phosphorylation of tau is an adaptive process associated with neuronal plasticity in hibernating animals
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JOURNAL OF NEUROSCIENCE (2003)
Impaired response to interferon-α/β and lethal viral disease in human STAT1 deficiency
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NATURE GENETICS (2003)
Programmed cell death in amyotrophic lateral sclerosis
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JOURNAL OF CLINICAL INVESTIGATION (2003)
Latent herpesvirus infection in human trigeminal ganglia causes chronic immune response
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AMERICAN JOURNAL OF PATHOLOGY (2003)
Central nervous system apoptosis in human herpes simplex virus and cytomegalovirus encephalitis
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JOURNAL OF INFECTIOUS DISEASES (2002)
Involvement of double-stranded RNA-dependent protein kinase and phosphorylation of eukaryotic initiation factor-2α in neuronal degeneration
RCC Chang et al.
JOURNAL OF NEUROCHEMISTRY (2002)
Inflammation in neurodegenerative disease - A double-edged sword
T Wyss-Coray et al.
NEURON (2002)
Role of IFN-γ and tumor necrosis factor-α in herpes simplex virus type 1 infection
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JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2002)
Up-regulation of the inflammatory cytokines IFN-γ and IL-12 and down-regulation of IL-4 in cerebral cortex regions of APPSWE transgenic mice
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JOURNAL OF NEUROIMMUNOLOGY (2002)
Regulation of starvation- and virus-induced autophagy by the eIF2α kinase signaling pathway
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Herpes simplex type 1 infects and establishes latency in the brain and trigerminal ganglia during primary infection of the lip in cotton rats and mice
G Lewandowski et al.
ARCHIVES OF VIROLOGY (2002)
Amyloid-beta peptides are cytotoxic to oligodendrocytes
J Xu et al.
JOURNAL OF NEUROSCIENCE (2001)
Herpes simplex virus type 1 latency in the murine nervous system is associated with oxidative damage to neurons
T Valyi-Nagy et al.
VIROLOGY (2000)
Difference in pathogenesis between herpes simplex virus type 1 encephalitis and tick-borne encephalitis demonstrated by means of cerebrospinal fluid markers of glial and neuronal destruction
M Studahl et al.
JOURNAL OF NEUROLOGY (2000)
Immunocytochemical characterization of long-term persistent immune activation in human brain after herpes simplex encephalitis
A Lellouch-Tubiana et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2000)
Inflammation and Alzheimer's disease
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NEUROBIOLOGY OF AGING (2000)
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