4.7 Article

Protein PGLYRP1/Tag7 Peptides Decrease the Proinflammatory Response in Human Blood Cells and Mouse Model of Diffuse Alveolar Damage of Lung through Blockage of the TREM-1 and TNFR1 Receptors

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Allergy

COVID-19 risk stratification algorithms based on sTREM-1 and IL-6 in emergency department

Mathias Van Singer et al.

Summary: This study found that specific biomarkers in the concentrations at clinical presentation in the emergency department of COVID-19 patients had good accuracy in predicting 30-day intubation/mortality and oxygen requirement, serving as potential early triage tools for identifying patients with adverse outcomes.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2021)

Review Biochemistry & Molecular Biology

Rheumatoid Arthritis in the View of Osteoimmunology

Melanie Aureal et al.

Summary: Rheumatoid arthritis is characterized by chronic synovial inflammation and irreversible bone erosions. Osteoclast-mediated bone resorption is the main cause of articular bone erosions, with autoantibodies, pro-inflammatory cytokines, and other regulating factors playing important roles in this process.

BIOMOLECULES (2021)

Article Biochemistry & Molecular Biology

Hsp70 Interacts with the TREM-1 Receptor Expressed on Monocytes and Thereby Stimulates Generation of Cytotoxic Lymphocytes Active against MHC-Negative Tumor Cells

Tatiana N. Sharapova et al.

Summary: The study demonstrates that the major heat shock protein 70 (Hsp70) can bind to and activate the innate immunity receptor TREM-1, leading to the production of inflammatory cytokines in monocytes and enhanced cytotoxic activity of lymphocytes against tumor cells.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Immunology

A 8-mer Peptide of PGLYRP1/Tag7 Innate Immunity Protein Binds to TNFR1 Receptor and Inhibits TNFα-Induced Cytotoxic Effect and Inflammation

Georgii B. Telegin et al.

Summary: The novel peptide 17.1A derived from PGLYRP1/Tag7 protein inhibits TNF receptor 1 (TNFR1) activation, showing anti-inflammatory and protective effects in a mouse model of arthritis. This peptide has potential as a therapeutic agent for autoimmune arthritis and other diseases.

FRONTIERS IN IMMUNOLOGY (2021)

Review Immunology

Immune dysregulation and system pathology in COVID-19

Muhammad Jamal et al.

Summary: COVID-19, caused by the novel coronavirus, has led to a global public health crisis with significant confirmed cases and mortalities. Patients exhibit a dysregulated immune response characterized by cytokine storm, increasing the mortality rate. Treatment strategies should focus on antiviral drugs, immunomodulators, and addressing underlying comorbidities.

VIRULENCE (2021)

Review Microbiology

The Innate Immune System: Fighting on the Front Lines or Fanning the Flames of COVID-19?

Julia L. McKechnie et al.

CELL HOST & MICROBE (2020)

Article Immunology

Comprehensive mapping of immune perturbations associated with severe COVID-19

Leticia Kuri-Cervantes et al.

SCIENCE IMMUNOLOGY (2020)

Review Allergy

Immune responses in COVID-19 and potential vaccines: Lessons learned from SARS and MERS epidemic

Eakachai Prompetchara et al.

ASIAN PACIFIC JOURNAL OF ALLERGY AND IMMUNOLOGY (2020)

Article Medicine, General & Internal

Risk factors for the exacerbation of patients with 2019 Novel Coronavirus: A meta-analysis

Jinqiu Zhao et al.

INTERNATIONAL JOURNAL OF MEDICAL SCIENCES (2020)

Article Agriculture, Dairy & Animal Science

Expression and Purification of a Functional Porcine Soluble Triggering Receptor Expressed on Myeloid Cells 1

Hui Li et al.

ANIMAL BIOTECHNOLOGY (2017)

Article Biochemistry & Molecular Biology

Tag7 (PGLYRP1) in Complex with Hsp70 Induces Alternative Cytotoxic Processes in Tumor Cells via TNFR1 Receptor

Denis V. Yashin et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2015)

Article Immunology

Cutting Edge: Identification of Neutrophil PGLYRP1 as a Ligand for TREM-1

Christine B. Read et al.

JOURNAL OF IMMUNOLOGY (2015)

Article Medicine, General & Internal

Acute Respiratory Distress Syndrome The Berlin Definition

V. Marco Ranieri et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2012)

Review Immunology

Pathogen Recognition by the Innate Immune System

Himanshu Kumar et al.

INTERNATIONAL REVIEWS OF IMMUNOLOGY (2011)

Review Biochemistry & Molecular Biology

Targeting HMGB1 in inflammation

Huan Yang et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2010)

Article Immunology

TREM-1 expression in macrophages is regulated at transcriptional level by NF-κB and PU.1

Heng Zeng et al.

EUROPEAN JOURNAL OF IMMUNOLOGY (2007)

Article Immunology

IL-4 induces in vivo production of IFN-γ by NK and NKT cells

Suzanne C. Morris et al.

JOURNAL OF IMMUNOLOGY (2006)

Article Biochemical Research Methods

Tricine-SDS-PAGE

Hermann Schaegger

NATURE PROTOCOLS (2006)

Article Biochemistry & Molecular Biology

Peptidoglycan recognition protein Tag7 forms a cytotoxic complex with heat shock protein 70 in solution and in lymphocytes

LP Sashchenko et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Crystal structure of the human myeloid cell activating receptor TREM-1

S Radaev et al.

STRUCTURE (2003)