Cellular and Molecular Targets for Non-Invasive, Non-Pharmacological Therapeutic/Rehabilitative Interventions in Acute Ischemic Stroke

Review Neurosciences

The Relation of the Brain-Derived Neurotrophic Factor with MicroRNAs in Neurodegenerative Diseases and Ischemic Stroke

Ceren Eyileten et al.

Summary: BDNF plays a crucial role in nervous system development and the pathogenesis of neurodegenerative diseases, while miRNAs may serve as potential biomarkers and therapeutic targets.

MOLECULAR NEUROBIOLOGY (2021)

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Review Clinical Neurology

Neurogenesis After Stroke: A Therapeutic Perspective

Abir A. Rahman et al.

Summary: Stroke is a major cause of death and disability globally, but therapeutic options are limited. Neurogenesis induced by stroke injury is of therapeutic interest. Understanding the interplay between neuroinflammation and neurogenesis is crucial for future stroke therapy development.

TRANSLATIONAL STROKE RESEARCH (2021)

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Article Biochemistry & Molecular Biology

TRPM2 in ischemic stroke: Structure, molecular mechanisms, and drug intervention

Qing Wang et al.

Summary: Ischemic stroke has a high lethality rate globally, with calcium overload being one of the mechanisms of cerebral ischemia. TRPM2 activation in cerebral ischemia leads to abnormal intracellular Ca2+ accumulation and cell death, highlighting its potential as a therapeutic target. Insights into TRPM2's expression, structure, function, and inhibitors provide avenues for developing new drugs and potent therapeutic approaches for treating ischemic stroke.

CHANNELS (2021)

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Review Neurosciences

Long Non-coding RNAs as Promising Therapeutic Approach in Ischemic Stroke: a Comprehensive Review

Marta Wolska et al.

Summary: Ischemic stroke (IS) is a major cause of disability and mortality worldwide, with long non-coding RNAs (lncRNAs) being increasingly recognized for their significant role in IS, particularly in ischemic reperfusion injury (I/R injury) and their potential as therapeutic approaches.

MOLECULAR NEUROBIOLOGY (2021)

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Article Multidisciplinary Sciences

The effects of bathing in neutral bicarbonate ion water

Tomoe Yamazaki et al.

Summary: Studies have shown that percutaneously absorbed carbon dioxide can be converted into bicarbonate ions, which act on endothelial cells to increase nitric oxide production, thereby improving blood flow.

SCIENTIFIC REPORTS (2021)

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Review Neurosciences

Neuroprotection by Transcranial Direct Current Stimulation in Rodent Models of Focal Ischemic Stroke: A Meta-Analysis

Jiapeng Huang et al.

Summary: This systematic review evaluated the effects of different tDCS paradigms in reducing infarct size and improving neurological deficit in rodent models of ischemic stroke. The results suggest that cathodal tDCS may be a promising avenue for rehabilitation from focal ischemic stroke, but caution should be taken due to the low overall quality of included studies. Future research is needed to investigate the mechanism of tDCS in clinically relevant stroke models and find an optimal treatment protocol.

FRONTIERS IN NEUROSCIENCE (2021)

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Article Biochemistry & Molecular Biology

The Effects of Atorvastatin on Global Cerebral Ischemia-Induced Neuronal Death

A. Ra Kho et al.

Summary: The study shows that atorvastatin can reduce neuronal death, oxidative stress, inflammation, and blood-brain barrier disruption in global cerebral ischemia, improving cognitive function. Additionally, atorvastatin can also reduce endothelial cell damage and VV proliferation. These results suggest that atorvastatin may be an effective option in managing global cerebral ischemia.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

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Article Clinical Neurology

Cathodal Transcranial Direct Current Stimulation in Acute Ischemic Stroke Pilot Randomized Controlled Trial

Estelle Pruvost-Robieux et al.

Summary: The study aimed to evaluate the feasibility and safety of C-tDCS in reducing infarct growth in hyperacute middle cerebral artery stroke patients. While no significant difference was found between active and sham groups, there was a potential benefit of C-tDCS in patients with high NIH Stroke Scale score or large vessel occlusion. Further randomized trials targeting these populations may be warranted.

STROKE (2021)

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Review Medicine, General & Internal

PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews

Matthew J. Page et al.

Summary: The methods and results of systematic reviews should be reported in sufficient detail to allow users to assess trustworthiness. PRISMA 2020 aims to improve the transparency and completeness of systematic review reporting, in hopes of guiding more accurate and transparent reporting.

BMJ-BRITISH MEDICAL JOURNAL (2021)

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Review Allergy

Hydrogen sulfide as a novel biomarker of asthma and chronic obstructive pulmonary disease

Yasuhito Suzuki et al.

Summary: Hydrogen sulfide (H2S) is recognized as the third important gas-signaling molecule, with dual effects of anti-inflammatory and antioxidant properties, but potentially pro-inflammatory under certain conditions. In respiratory disorders, H2S has shown promise as a novel biomarker for predicting asthma risks and identifying inflammatory phenotypes for personalized treatment.

ALLERGOLOGY INTERNATIONAL (2021)

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Review Biochemistry & Molecular Biology

Endothelium as a Source and Target of H2S to Improve Its Trophism and Function

Valerio Ciccone et al.

Summary: The vascular endothelium is composed of a single layer of cells that regulate blood flow homeostasis and tissue metabolic demands. Gasotransmitters such as nitric oxide and hydrogen sulfide, produced by endothelial cells, play a crucial role in maintaining vascular physiological functions. By regulating vascular function, H2S can enhance the biology and function of endothelial cells.

ANTIOXIDANTS (2021)

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Article Medicine, General & Internal

Circulating miR-155 and JAK2/STAT3 Axis in Acute Ischemic Stroke Patients and Its Relation to Post-Ischemic Inflammation and Associated Ischemic Stroke Risk Factors

Noha Adly Sadik et al.

Summary: The study found that in patients with acute ischemic stroke, circulating expressions of miR-155, JAK2/STAT3, and TNF-alpha are elevated, potentially triggering post-stroke cellular inflammation and associated with certain risk factors. MiR-155 could serve as a potential inflammatory biomarker for acute ischemic stroke. Further clinical studies are needed to determine the exact role of miRNAs and different signal transduction expressions in the acute ischemic stroke stage.

INTERNATIONAL JOURNAL OF GENERAL MEDICINE (2021)

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Article Multidisciplinary Sciences

Ras-like Gem GTPase induced by Npas4 promotes activity-dependent neuronal tolerance for ischemic stroke

Hiroo Takahashi et al.

Summary: The study demonstrates that the collaborative action of activity-dependent transcription factor Npas4 and Gem gene can promote neuroprotection, reduce neuronal cell death after stroke, and serve as a potential new drug target.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)

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Article Chemistry, Analytical

Prediction of Myoelectric Biomarkers in Post-Stroke Gait

Iqram Hussain et al.

Summary: EMG was used to evaluate the muscular activity of stroke patients and healthy adults, showing significant differences in various EMG parameters between the two groups. The neural network model demonstrated the highest classification performance, aiding in understanding stroke-induced gait changes and determining post-stroke rehabilitation strategies.

SENSORS (2021)

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Review Immunology

Immune Cells in the BBB Disruption After Acute Ischemic Stroke: Targets for Immune Therapy?

Yan-mei Qiu et al.

Summary: Blood-Brain Barrier (BBB) disruption is a crucial pathophysiological process in acute ischemic stroke, where the rapid activation of immune cells plays a critical role. Infiltrating immune cells increase BBB permeability, causing microvascular disorder, but also promote BBB repair and angiogenesis. Understanding the inflammatory mechanisms behind BBB disruption can lead to the development of more effective therapeutics for acute ischemic stroke.

FRONTIERS IN IMMUNOLOGY (2021)

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Review Clinical Neurology

Mechanisms of fibrinolysis resistance and potential targets for thrombolysis in acute ischaemic stroke: lessons from retrieved stroke emboli

Waleed Brinjikji et al.

Summary: The article discusses the increasing interest and understanding in the histological composition of retrieved stroke emboli, particularly in its impact on mechanical thrombectomy procedures. However, the mechanisms underlying the low response to fibrinolytic therapy remain poorly understood. Analyzing the composition of clots with a focus on histological and ultrastructural characteristics offers unique insights into the mechanisms of resistance to fibrinolysis.

STROKE AND VASCULAR NEUROLOGY (2021)

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Article Neurosciences

Quantitative Evaluation of Task-Induced Neurological Outcome after Stroke

Iqram Hussain et al.

Summary: Electroencephalography (EEG) is a prospective predictive method for acute stroke prognostics, neurological outcome, and post-stroke rehabilitation management. This study quantified EEG features to understand task-induced neurological declines due to stroke and evaluated biomarkers to distinguish between stroke patients and healthy adults. The statistical results showed that alpha, theta, and delta activities are biomarkers that classify stroke patients and healthy adults during motor and cognitive states. Using machine-learning, the C5.0 model achieved high accuracy in classifying stroke patients and healthy adults during different tasks.

BRAIN SCIENCES (2021)

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Review Biochemistry & Molecular Biology

Non-invasive, non-pharmacological/bio-technological interventions towards neurorestoration upshot after ischemic stroke, in adults-systematic, synthetic, literature review

Gelu Onose et al.

Summary: Cerebrovascular accident (CVA) is a life-threatening condition with severe and permanent disability potential. Research suggests that brain neurorestoration/repair may occur later than previously thought post-stroke, with conflicting outcomes. Continued interdisciplinary research efforts are needed in this complex domain.

FRONTIERS IN BIOSCIENCE-LANDMARK (2021)

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Article Computer Science, Information Systems

Big-ECG: Cardiographic Predictive Cyber-Physical System for Stroke Management

Iqram Hussain et al.

Summary: The study assessed the feasibility of a cyber-physical cardiac monitoring system for classifying stroke patients and healthy adults, proposing the Big-ECG system for stroke management. Analysis of ECG data revealed distinctive biomarkers for stroke patients compared to healthy controls, with the Random Trees model showing the best classification performance.

IEEE ACCESS (2021)

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Review Rehabilitation

Therapeutic gases used in balneotherapy and rehabilitation medicine - scientific relevance in the last ten years (2011 - 2020) - Synthetic literature review

Constantin Munteanu et al.

Summary: This synthetic review examines the main uses and physiological mechanisms of therapeutic gases, which have shown potential therapeutic effects in various brain disease states. However, due to the complexity and diversity of the medical gases field, systematic literature reviews are challenging to conduct, indicating the need for further research to fully understand the mechanisms and importance of therapeutic gases.

BALNEO AND PRM RESEARCH JOURNAL (2021)

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Article Hematology

Structural analysis of ischemic stroke thrombi: histological indications for therapy resistance

Senna Staessens et al.

HAEMATOLOGICA (2020)

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Review Neurosciences

Pharmacological Interventions and Rehabilitation Approach for Enhancing Brain Self-repair and Stroke Recovery

Rafal Szelenberger et al.

CURRENT NEUROPHARMACOLOGY (2020)

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Article Clinical Neurology

Transcranial direct current stimulation associated with physical-therapy in acute stroke patients - A randomized, triple blind, sham-controlled study

Stephen Bornheim et al.

BRAIN STIMULATION (2020)

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Review Neurosciences

Hypoxic-ischemic-related cerebrovascular changes and potential therapeutic strategies in the neonatal brain

Clemence Disdier et al.

JOURNAL OF NEUROSCIENCE RESEARCH (2020)

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Review Oncology

Modulators of microglia activation and polarization in ischemic stroke

Cheng-Ting Jiang et al.

MOLECULAR MEDICINE REPORTS (2020)

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Article Neurosciences

Hyperbaric oxygen therapy improves neurocognitive functions of post-stroke patients - a retrospective analysis

Amir Hadanny et al.

RESTORATIVE NEUROLOGY AND NEUROSCIENCE (2020)

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Article Neurosciences

Cathodal tDCS exerts neuroprotective effect in rat brain after acute ischemic stroke

Ke-Ying Zhang et al.

BMC NEUROSCIENCE (2020)

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Review Neurosciences

Brain-Derived Neurotrophic Factor and Its Potential Therapeutic Role in Stroke Comorbidities

Wei Liu et al.

NEURAL PLASTICITY (2020)

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Review Physiology

Neutrophil-Related Oxidants Drive Heart and Brain Remodeling After Ischemia/Reperfusion Injury

Federico Carbone et al.

FRONTIERS IN PHYSIOLOGY (2020)

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Article Biochemistry & Molecular Biology

Restoration of L-OPA1 alleviates acute ischemic stroke injury in rats via inhibiting neuronal apoptosis and preserving mitochondrial function

Yongxing Lai et al.

REDOX BIOLOGY (2020)

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Article Cell Biology

Electroacupuncture ameliorates cerebral ischemia/reperfusion injury by suppressing autophagy via the SIRT1-FOXO1 signaling pathway

Zhi-Gang Mei et al.

Aging-US (2020)

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Article Neurosciences

Evaluating the Efficacy of Taurodeoxycholic Acid in Providing Otoprotection Using anin vitroModel of Electrode Insertion Trauma

Viraj Shah et al.

FRONTIERS IN MOLECULAR NEUROSCIENCE (2020)

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Review Neurosciences

Application of Stem Cells in Stroke: A Multifactorial Approach

Manisha Singh et al.

FRONTIERS IN NEUROSCIENCE (2020)

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Article Oncology

Exogenous hydrogen sulfide reduces atrial remodeling and atrial fibrillation induced by diabetes mellitus via activation of the PI3K/Akt/eNOS pathway

Xiaofei Xue et al.

MOLECULAR MEDICINE REPORTS (2020)

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Review Pharmacology & Pharmacy

Hydrogen sulfide: An endogenous regulator of the immune system

Nahzli Dilek et al.

PHARMACOLOGICAL RESEARCH (2020)

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Article Computer Science, Information Systems

HealthSOS: Real-Time Health Monitoring System for Stroke Prognostics

Iqram Hussain et al.

IEEE ACCESS (2020)

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Review Clinical Neurology

Enhancing Brain Plasticity to Promote Stroke Recovery

Fan Su et al.

FRONTIERS IN NEUROLOGY (2020)

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Article Cell Biology

Selective brain hypothermia-induced neuroprotection against focal cerebral ischemia/reperfusion injury is associated with Fis1 inhibition

Ya-Nan Tang et al.

NEURAL REGENERATION RESEARCH (2020)

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Review Cell Biology

Protective effect of hydrogen sulfide on oxidative stress-induced neurodegenerative diseases

Rubaiya Tabassum et al.

NEURAL REGENERATION RESEARCH (2020)

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Article Cell Biology

Paired associated magnetic stimulation promotes neural repair in the rat middle cerebral artery occlusion model of stroke

Bei-Yao Gao et al.

NEURAL REGENERATION RESEARCH (2020)

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Review Neurosciences

Role of Nitric Oxide and Hydrogen Sulfide in Ischemic Stroke and the Emergent Epigenetic Underpinnings

Parimala Narne et al.

MOLECULAR NEUROBIOLOGY (2019)

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Review Physiology

Emergent Prophylactic, Reparative and Restorative Brain Interventions for Infants Born Preterm With Cerebral Palsy

Megan Finch-Edmondson et al.

FRONTIERS IN PHYSIOLOGY (2019)

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Review Clinical Neurology

A Systemic Review of Functional Near-Infrared Spectroscopy for Stroke: Current Application and Future Directions

Muyue Yang et al.

FRONTIERS IN NEUROLOGY (2019)

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Review Critical Care Medicine

A New Vision for Therapeutic Hypothermia in the Era of Targeted Temperature Management: A Speculative Synthesis

Travis C. Jackson et al.

THERAPEUTIC HYPOTHERMIA AND TEMPERATURE MANAGEMENT (2019)

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Article Biochemistry & Molecular Biology

The Role of Astragaloside IV against Cerebral Ischemia/Reperfusion Injury: Suppression of Apoptosis via Promotion of P62-LC3-Autophagy

Yi Zhang et al.

MOLECULES (2019)

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Article Neurosciences

Acute and Post-acute Neuromodulation Induces Stroke Recovery by Promoting Survival Signaling, Neurogenesis, and Pyramidal Tract Plasticity

Ahmet B. Caglayan et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2019)

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Review Neurosciences

Rodent Models of Developmental Ischemic Stroke for Translational Research: Strengths and Weaknesses

Mariangela Gennaro et al.

NEURAL PLASTICITY (2019)

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Review Neurosciences

Mechanism and Treatment Related to Oxidative Stress in Neonatal Hypoxic-Ischemic Encephalopathy

Xingping Qin et al.

FRONTIERS IN MOLECULAR NEUROSCIENCE (2019)

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Article Medicine, Research & Experimental

Electroacupuncture Alleviates Ischemic Brain Injury by Inhibiting the miR-223/NLRP3 Pathway

Rong Sha et al.

MEDICAL SCIENCE MONITOR (2019)

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Article Neurosciences

An MRI Study of Neurovascular Restorative After Combination Treatment With Xiaoshuan Enteric-Coated Capsule and Enriched Environment in Rats After Stroke

Yu Zhan et al.

FRONTIERS IN NEUROSCIENCE (2019)

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Review Neurosciences

Modulation of Neural Activity for Myelination in the Central Nervous System

Elliot H. Choi et al.

FRONTIERS IN NEUROSCIENCE (2019)

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Review Biochemistry & Molecular Biology

Ischemia/Reperfusion Injury Revisited: An Overview of the Latest Pharmacological Strategies

Ricardo O. S. Soares et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

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Article Neurosciences

Melatonin protects against ischemic stroke by modulating microglia/macrophage polarization toward anti-inflammatory phenotype through STAT3 pathway

Zong-Jian Liu et al.

CNS NEUROSCIENCE & THERAPEUTICS (2019)

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Article Oncology

Innate/inflammatory bioregulation and clinical effectiveness of whole-body hyperthermia (balneotherapy) in elderly patients with osteoarthritis

Isabel Galvez et al.

INTERNATIONAL JOURNAL OF HYPERTHERMIA (2019)

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Review Neurosciences

Altered Neural Networks in the Papez Circuit: Implications for Cognitive Dysfunction after Cerebral Ischemia

Iris Escobar et al.

JOURNAL OF ALZHEIMERS DISEASE (2019)

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Article Immunology

Transplantation of mesenchymal stem cells genetically engineered to overexpress interleukin-10 promotes alternative inflammatory response in rat model of traumatic brain injury

S. T. Peruzzaro et al.

JOURNAL OF NEUROINFLAMMATION (2019)

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Article Cell Biology

Metformin Protects against Oxidative Stress Injury Induced by Ischemia/Reperfusion via Regulation of the lncRNA-H19/miR-148a-3p/Rock2 Axis

Jing Zeng et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2019)

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Review Neurosciences

The Importance of Therapeutic Time Window in the Treatment of Traumatic Brain Injury

Maliheh Mohamadpour et al.

FRONTIERS IN NEUROSCIENCE (2019)

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Article Pharmacology & Pharmacy

Design, synthesis and biological evaluation of chalcone analogues with novel dual antioxidant mechanisms as potential anti-ischemic stroke agents

Jiabing Wang et al.

ACTA PHARMACEUTICA SINICA B (2019)

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Review Clinical Neurology

Evidence and opportunities of hypothermia in acute ischemic stroke: Clinical trials of systemic versus selective hypothermia

Christian Huber et al.

BRAIN CIRCULATION (2019)

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Review Clinical Neurology

Cold blood perfusion for selective hypothermia in acute ischemic stroke

Thomas K. Mattingly et al.

BRAIN CIRCULATION (2019)

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Review Clinical Neurology

Therapeutic hypothermia: Applications in adults with acute ischemic stroke

Andrea M. Kuczynski et al.

BRAIN CIRCULATION (2019)

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Article Biochemistry & Molecular Biology

Cerebral ischemic stroke: cellular fate and therapeutic opportunities

Sibani Sarkar et al.

FRONTIERS IN BIOSCIENCE-LANDMARK (2019)

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Review Neurosciences

Potential Medications or Compounds Acting on Toll-like Receptors in Cerebral Ischemia

Man Li et al.

CURRENT NEUROPHARMACOLOGY (2018)

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Review Neurosciences

Mechanisms of Transcranial Magnetic Stimulation Treating on Post-stroke Depression

Xiaoqin Duan et al.

FRONTIERS IN HUMAN NEUROSCIENCE (2018)

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Review Biophysics

Salt water and skin interactions: new lines of evidence

Jose Manuel Carbajo et al.

INTERNATIONAL JOURNAL OF BIOMETEOROLOGY (2018)

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Review Biochemistry & Molecular Biology

Schisandra chinensis Fructus and Its Active Ingredients as Promising Resources for the Treatment of Neurological Diseases

Minyu Zhang et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

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Review Cell Biology

Acupuncture and neuroregeneration in ischemic stroke

Qwang-Yuen Chang et al.

NEURAL REGENERATION RESEARCH (2018)

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Review Cell Biology

Cerebral ischemia and neuroregeneration

Reggie H. C. Lee et al.

NEURAL REGENERATION RESEARCH (2018)

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Review Cell Biology

Free Radical Damage in Ischemia-Reperfusion Injury: An Obstacle in Acute Ischemic Stroke after Revascularization Therapy

Ming-Shuo Sun et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2018)

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Review Cell Biology

Cell Type-Specific Mechanisms in the Pathogenesis of Ischemic Stroke: The Role of Apoptosis Signal-Regulating Kinase 1

So Yeong Cheon et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2018)

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Article Neurosciences

Enhancing endogenous capacity to repair a stroke-damaged brain: An evolving field for stroke research

Li-Ru Zhao et al.

PROGRESS IN NEUROBIOLOGY (2018)

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Article Multidisciplinary Sciences

Inhibitory modulation of cytochrome c oxidase activity with specific near-infrared light wavelengths attenuates brain ischemia/reperfusion injury

Thomas H. Sanderson et al.

SCIENTIFIC REPORTS (2018)

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Review Polymer Science

Hydrogels-Assisted Cell Engraftment for Repairing the Stroke-Damaged Brain: Chimera or Reality

Daniel Gonzalez-Nieto et al.

POLYMERS (2018)

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Article Medicine, Research & Experimental

Electroacupuncture Inhibits Apoptosis of Peri-Ischemic Regions via Modulating p38, Extracellular Signal-Regulated Kinase (ERK1/2), and c-Jun N Terminal Kinases (JNK) in Cerebral Ischemia-Reperfusion-Injured Rats

Jiao Liu et al.

MEDICAL SCIENCE MONITOR (2018)

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Review Geriatrics & Gerontology

Effects of Therapeutic Hypothermia Combined with Other Neuroprotective Strategies on Ischemic Stroke: Review of Evidence

Zheng Zhang et al.

AGING AND DISEASE (2018)

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Article Behavioral Sciences

An overview of protective strategies against ischemia/reperfusion injury: The role of hyperbaric oxygen preconditioning

Ciprian Hentia et al.

BRAIN AND BEHAVIOR (2018)

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Review Clinical Neurology

Treatments to Promote Neural Repair after Stroke

Steven C. Cramer

JOURNAL OF STROKE (2018)

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Article Critical Care Medicine

Implementation of Targeted Temperature Management in a Patient with Cerebral Arterial Gas Embolism

Se Hyun Oh et al.

THERAPEUTIC HYPOTHERMIA AND TEMPERATURE MANAGEMENT (2018)

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Review Neurosciences

Physiological Roles and Therapeutic Potential of Ca2+ Activated Potassium Channels in the Nervous System

Aravind S. Kshatri et al.

FRONTIERS IN MOLECULAR NEUROSCIENCE (2018)

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Article Cell & Tissue Engineering

Non-Coding RNA in Acute Ischemic Stroke: Mechanisms, Biomarkers and Therapeutic Targets

Sheng-Wen Wang et al.

CELL TRANSPLANTATION (2018)

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Review Neurosciences

Mechanisms Involved in the Neuroprotection of Electroacupuncture Therapy for Ischemic Stroke

Ying Xing et al.

FRONTIERS IN NEUROSCIENCE (2018)

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Article Clinical Neurology

Design and Methodology of a Pilot Randomized Controlled Trial of Transcranial Direct Current Stimulation in Acute Middle Cerebra Artery Stroke (STICA)

Estelle Pruvost-Robieux et al.

FRONTIERS IN NEUROLOGY (2018)

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Review Clinical Neurology

Combination therapy for ischemic stroke: Novel approaches to lengthen therapeutic window of tissue plasminogen activator

Talia Knecht et al.

BRAIN CIRCULATION (2018)

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Review Cell Biology

Mitophagy, a potential therapeutic target for stroke

Ruiqiao Guan et al.

JOURNAL OF BIOMEDICAL SCIENCE (2018)

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Review Medicine, Research & Experimental

Heart Rate Variability as a Biomarker for Predicting Stroke, Post-stroke Complications and Functionality

Ty Lees et al.

BIOMARKER INSIGHTS (2018)

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Review Neurosciences

The Intersection of Central Dopamine System and Stroke: Potential Avenues Aiming at Enhancement of Motor Recovery

Annette Gower et al.

FRONTIERS IN SYNAPTIC NEUROSCIENCE (2018)

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Review Optics

Photobiomodulation and the brain: a new paradigm

Madison Hennessy et al.

JOURNAL OF OPTICS (2017)

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Article Clinical Neurology

Agreed definitions and a shared vision for new standards in stroke recovery research: The Stroke Recovery and Rehabilitation Roundtable taskforce

Julie Bernhardt et al.

INTERNATIONAL JOURNAL OF STROKE (2017)

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Review Rehabilitation

Cell biology considerations in Spinal Cord Injury - Review

Constantin Munteanu

BALNEO RESEARCH JOURNAL (2017)

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Article Clinical Neurology

Repetitive hyperbaric oxygen treatment increases insulin sensitivity in diabetes patients with acute intracerebral hemorrhage

Qian Xu et al.

NEUROPSYCHIATRIC DISEASE AND TREATMENT (2017)

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Article Oncology

Effects of hyperbaric oxygen therapy on RAGE and MCP-1 expression in rats with spinal cord injury

Yong Wang et al.

MOLECULAR MEDICINE REPORTS (2016)

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Article Cell Biology

AP39, a Mitochondria-Targeted Hydrogen Sulfide Donor, Supports Cellular Bioenergetics and Protects against Alzheimer's Disease by Preserving Mitochondrial Function in APP/PS1 Mice and Neurons

Feng-li Zhao et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)

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Article Clinical Neurology

Hydrogen Sulfide Attenuates Tissue Plasminogen Activator-Induced Cerebral Hemorrhage Following Experimental Stroke

Hui Liu et al.

TRANSLATIONAL STROKE RESEARCH (2016)

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Article Biochemistry & Molecular Biology

Signaling pathways involved in HSP32 induction by hyperbaric oxygen in rat spinal neurons

Guoyang Huang et al.

REDOX BIOLOGY (2016)

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Article Clinical Neurology

The Specific Requirements of Neural Repair Trials for Stroke

Bruce H. Dobkin et al.

NEUROREHABILITATION AND NEURAL REPAIR (2016)

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Review Medicine, Research & Experimental

Hyperbaric oxygen therapy and preconditioning for ischemic and hemorrhagic stroke

Sheng-li Hu et al.

MEDICAL GAS RESEARCH (2016)

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Review Medicine, Research & Experimental

Molecular hydrogen: a therapeutic antioxidant and beyond

Lei Huang

MEDICAL GAS RESEARCH (2016)

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Article Endocrinology & Metabolism

Hydrogen Sulfide Improves Wound Healing via Restoration of Endothelial Progenitor Cell Functions and Activation of Angiopoietin-1 in Type 2 Diabetes

Fang Liu et al.

DIABETES (2014)

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Article Endocrinology & Metabolism

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