相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Ibrutinib reduces neutrophil infiltration ,preserves neural tissue and enhances locomotor recovery in mouse contusion model of spinal cord injury
Somayyeh Torabi et al.
ANATOMY & CELL BIOLOGY (2021)
BTK blockers make headway in multiple sclerosis
Elie Dolgin
NATURE BIOTECHNOLOGY (2021)
Therapeutic Targeting of Autoreactive B Cells: Why, How, and When?
Zachary C. Stensland et al.
BIOMEDICINES (2021)
Bleeding by Bruton Tyrosine Kinase-Inhibitors: Dependency on Drug Type and Disease
Philipp von Hundelshausen et al.
CANCERS (2021)
Comparative Analysis of BTK Inhibitors and Mechanisms Underlying Adverse Effects
H. Yesid Estupinan et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
The Role of B Cells and B Cell Therapies in Immune-Mediated Liver Diseases
Tamsin Cargill et al.
FRONTIERS IN IMMUNOLOGY (2021)
B Cell Activation and Escape of Tolerance Checkpoints: Recent Insights from Studying Autoreactive B Cells
Carlo G. Bonasia et al.
CELLS (2021)
Innate Immune Functions of Astrocytes are Dependent Upon Tumor Necrosis Factor-Alpha
Kyla R. Rodgers et al.
SCIENTIFIC REPORTS (2020)
Inhibition of Bruton's tyrosine kinase interferes with pathogenic B-cell development in inflammatory CNS demyelinating disease
Sebastian Torke et al.
ACTA NEUROPATHOLOGICA (2020)
Inhibition of Bruton tyrosine kinase in patients with severe COVID-19
Mark Roschewski et al.
SCIENCE IMMUNOLOGY (2020)
Platelet function and bleeding in chronic lymphocytic leukemia and mantle cell lymphoma patients on ibrutinib
Elena A. Dmitrieva et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2020)
Astrocyte Reactivity: Subtypes, States, and Functions in CNS Innate Immunity
Michael V. Sofroniew
TRENDS IN IMMUNOLOGY (2020)
Inhibition of NOX2 signaling limits pain-related behavior and improves motor function in male mice after spinal cord injury: Participation of IL-10/miR-155 pathways
Boris Sabirzhanov et al.
BRAIN BEHAVIOR AND IMMUNITY (2019)
Inhibition of Bruton's Tyrosine Kinase Modulates Microglial Phagocytosis: Therapeutic Implications for Alzheimer's Disease
James Keaney et al.
JOURNAL OF NEUROIMMUNE PHARMACOLOGY (2019)
Repositioning Flubendazole for Spinal Cord Injury
Chen Guang Yu et al.
JOURNAL OF NEUROTRAUMA (2019)
Traumatic Spinal Cord Injury: An Overview of Pathophysiology, Models and Acute Injury Mechanisms
Arsalan Alizadeh et al.
FRONTIERS IN NEUROLOGY (2019)
The Role of Bruton's Tyrosine Kinase in Immune Cell Signaling and Systemic Autoimmunity
Jasper Rip et al.
CRITICAL REVIEWS IN IMMUNOLOGY (2018)
Targeting B Cells and Plasma Cells in Autoimmune Diseases
Katharina Hofmann et al.
FRONTIERS IN IMMUNOLOGY (2018)
A pilot study of lower doses of ibrutinib in patients with chronic lymphocytic leukemia
Lisa S. Chen et al.
BLOOD (2018)
Ibrutinib suppresses LPS-induced neuroinflammatory responses in BV2 microglial cells and wild-type mice
Hye Yeon Nam et al.
JOURNAL OF NEUROINFLAMMATION (2018)
Elevated Autoantibodies in Subacute Human Spinal Cord Injury Are Naturally Occurring Antibodies
Angel Arevalo-Martin et al.
FRONTIERS IN IMMUNOLOGY (2018)
Characterization of the Antibody Response after Cervical Spinal Cord Injury
Antigona Ulndreaj et al.
JOURNAL OF NEUROTRAUMA (2017)
Neurotoxic reactive astrocytes are induced by activated microglia
Shane A. Liddelow et al.
NATURE (2017)
Bruton's Tyrosine Kinase: An Emerging Key Player in Innate Immunity
Alexander N. R. Weber et al.
FRONTIERS IN IMMUNOLOGY (2017)
Systemic and Local Cytokine Profile following Spinal Cord Injury in Rats: A Multiplex Analysis
Yana O. Mukhamedshina et al.
FRONTIERS IN NEUROLOGY (2017)
Altered B cell signalling in autoimmunity
David J. Rawlings et al.
NATURE REVIEWS IMMUNOLOGY (2017)
The role of Bruton's tyrosine kinase in autoimmunity and implications for therapy
Leslie J. Crofford et al.
EXPERT REVIEW OF CLINICAL IMMUNOLOGY (2016)
Cytokine and Growth Factor Activation In Vivo and In Vitro after Spinal Cord Injury
Elisa Garcia et al.
MEDIATORS OF INFLAMMATION (2016)
B-Cell Depletion with CD20 Antibodies as New Approach in the Treatment of Inflammatory and Immunological Events Associated with Spinal Cord Injury
Giovanna Casili et al.
NEUROTHERAPEUTICS (2016)
Astrocytes: Key Regulators of Neuroinflammation
Emanuela Colombo et al.
TRENDS IN IMMUNOLOGY (2016)
Spontaneous Recovery of Reflex Voiding Following Spinal Cord Injury Mediated by Anti-inflammatory and Neuroprotective Factors
Pradeep Tyagi et al.
UROLOGY (2016)
Ibrutinib modifies the function of monocyte/macrophage population in chronic lymphocytic leukemia
Stefania Fiorcari et al.
ONCOTARGET (2016)
Macrophage activation and its role in repair and pathology after spinal cord injury
John C. Gensel et al.
BRAIN RESEARCH (2015)
B cells responses and cytokine production are regulated by their immune microenvironment
Monica I. Vazquez et al.
CYTOKINE (2015)
Traumatic Spinal Cord Injury in the United States, 1993-2012
Nitin B. Jain et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2015)
Delayed Imatinib Treatment for Acute Spinal Cord Injury: Functional Recovery and Serum Biomarkers
Jacob Kjell et al.
JOURNAL OF NEUROTRAUMA (2015)
Innate and adaptive immune responses in the CNS
Ari Waisman et al.
LANCET NEUROLOGY (2015)
Control of autoimmune CNS inflammation by astrocytes
Veit Rothhammer et al.
SEMINARS IN IMMUNOPATHOLOGY (2015)
Bruton's tyrosine kinase is essential for NLRP3 inflammasome activation and contributes to ischaemic brain injury
Minako Ito et al.
NATURE COMMUNICATIONS (2015)
Btk inhibition suppresses agonist-induced human macrophage activation and inflammatory gene expression in RA synovial tissue explants
Linda M. Hartkamp et al.
ANNALS OF THE RHEUMATIC DISEASES (2015)
Immune dysfunction and chronic inflammation following spinal cord injury
D. J. Allison et al.
SPINAL CORD (2015)
Bruton's tyrosine kinase inhibitors for the treatment of rheumatoid arthritis
Jennifer A. Whang et al.
DRUG DISCOVERY TODAY (2014)
Lymphocytes and autoimmunity after spinal cord injury
T. Bucky Jones
EXPERIMENTAL NEUROLOGY (2014)
Modulating Inflammatory Cell Responses to Spinal Cord Injury: All in Good Time
Amy L. Bowes et al.
JOURNAL OF NEUROTRAUMA (2014)
Utility and safety of rituximab in pediatric autoimmune and inflammatory CNS disease
Russell C. Dale et al.
NEUROLOGY (2014)
FENBENDAZOLE IMPROVES PATHOLOGICAL AND FUNCTIONAL RECOVERY FOLLOWING TRAUMATIC SPINAL CORD INJURY
C. G. Yu et al.
NEUROSCIENCE (2014)
Btk Regulates Macrophage Polarization in Response to Lipopolysaccharide
Joan Ni Gabhann et al.
PLOS ONE (2014)
Calpain 1 Knockdown Improves Tissue Sparing and Functional Outcomes after Spinal Cord Injury in Rats
Chen Guang Yu et al.
JOURNAL OF NEUROTRAUMA (2013)
B-Cell Maturation Antigen, A Proliferation-Inducing Ligand, and B-Cell Activating Factor Are Candidate Mediators of Spinal Cord Injury-Induced Autoimmunity
Jonah W. Saltzman et al.
JOURNAL OF NEUROTRAUMA (2013)
Bruton tyrosine kinase inhibitor ibrutinib (PCI-32765)
Jan A. Burger et al.
LEUKEMIA & LYMPHOMA (2013)
Btk levels set the threshold for B-cell activation and negative selection of autoreactive B cells in mice
Laurens P. Kil et al.
BLOOD (2012)
Innate immunity in the central nervous system
Richard M. Ransohoff et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Modulating proximal cell signaling by targeting Btk ameliorates humoral autoimmunity and end-organ disease in murine lupus
Jack Hutcheson et al.
ARTHRITIS RESEARCH & THERAPY (2012)
A Grading System To Evaluate Objectively the Strength of Pre-Clinical Data of Acute Neuroprotective Therapies for Clinical Translation in Spinal Cord Injury
Brian K. Kwon et al.
JOURNAL OF NEUROTRAUMA (2011)
Emerging Concepts in Myeloid Cell Biology after Spinal Cord Injury
Alicia L. Hawthorne et al.
NEUROTHERAPEUTICS (2011)
The Bruton tyrosine kinase inhibitor PCI-32765 ameliorates autoimmune arthritis by inhibition of multiple effector cells
Betty Y. Chang et al.
ARTHRITIS RESEARCH & THERAPY (2011)
Quantitative analysis of cellular inflammation after traumatic spinal cord injury: evidence for a multiphasic inflammatory response in the acute to chronic environment
Kevin D. Beck et al.
BRAIN (2010)
Acute and Chronic Deficits in the Urinary Bladder after Spinal Contusion Injury in the Adult Rat
Juan J. Herrera et al.
JOURNAL OF NEUROTRAUMA (2010)
B cells and autoantibodies: complex roles in CNS injury
Daniel P. Ankeny et al.
TRENDS IN IMMUNOLOGY (2010)
Pathogenic antibodies are active participants in spinal cord injury
Gregory A. Dekaban et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
B cells produce pathogenic antibodies and impair recovery after spinal cord injury in mice
Daniel P. Ankeny et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord
Kristina A. Kigerl et al.
JOURNAL OF NEUROSCIENCE (2009)
FTY720 Reduces Inflammation and Promotes Functional Recovery after Spinal Cord Injury
Kangmin D. Lee et al.
JOURNAL OF NEUROTRAUMA (2009)
Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury
Dustin J. Donnelly et al.
EXPERIMENTAL NEUROLOGY (2008)
Impaired antibody synthesis after spinal cord injury is level dependent and is due to sympathetic nervous system dysregulation
Kurt M. Lucin et al.
EXPERIMENTAL NEUROLOGY (2007)
The cellular inflammatory response in human spinal cords after injury
Jennifer C. Fleming et al.
BRAIN (2006)
Differential activation of astrocytes by innate and adaptive immune stimuli
PA Carpentier et al.
GLIA (2005)
B-lymphocytes, innate immunity, and autoimmunity
M Viau et al.
CLINICAL IMMUNOLOGY (2005)
Reactive astrocytes protect tissue and preserve function after spinal cord injury
JR Faulkner et al.
JOURNAL OF NEUROSCIENCE (2004)
CD138 (Syndecan-1), a plasma cell marker - Immunohistochemical profile in hematopoietic and nonhematopoietic neoplasms
FP O'Connell et al.
AMERICAN JOURNAL OF CLINICAL PATHOLOGY (2004)
Pleiotropic consequences of Bruton tyrosine kinase deficiency in myeloid lineages lead to poor inflammatory responses
A Mangla et al.
BLOOD (2004)
Reduced dosage of Bruton's tyrosine kinase uncouples B cell hyperresponsiveness from autoimmunity in lyn-/- mice
LR Whyburn et al.
JOURNAL OF IMMUNOLOGY (2003)
Experimental modeling of spinal cord injury: Characterization of a force-defined injury device
SW Scheff et al.
JOURNAL OF NEUROTRAUMA (2003)
Elevated serum titers of proinflammatory cytokines and CNS autoantibodies in patients with chronic spinal cord injury
KC Hayes et al.
JOURNAL OF NEUROTRAUMA (2002)
Pathological CNS autoimmune disease triggered by traumatic spinal cord injury: Implications for autoimmune vaccine therapy
TB Jones et al.
JOURNAL OF NEUROSCIENCE (2002)
Enhanced expression of Iba1, ionized calcium-binding adapter molecule 1, after transient focal cerebral ischemia in rat brain
D Ito et al.
STROKE (2001)