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Surface Modification of Bacterial Cellulose for Biomedical Applications

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MDPI
DOI: 10.3390/ijms23020610

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bacterial cellulose; surface chemistry; surface analysis; surface functionalization; interface; tissue engineering; bactericidal

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Bacterial cellulose is a naturally occurring polysaccharide with various biomedical applications. It possesses remarkable biocompatibility and mechanical properties, making it suitable for tissue replacement. This review discusses the structure, mechanical properties, and characterization techniques of bacterial cellulose. It also explores the functionalization and surface modification methods to enhance its functionality.
Bacterial cellulose is a naturally occurring polysaccharide with numerous biomedical applications that range from drug delivery platforms to tissue engineering strategies. BC possesses remarkable biocompatibility, microstructure, and mechanical properties that resemble native human tissues, making it suitable for the replacement of damaged or injured tissues. In this review, we will discuss the structure and mechanical properties of the BC and summarize the techniques used to characterize these properties. We will also discuss the functionalization of BC to yield nanocomposites and the surface modification of BC by plasma and irradiation-based methods to fabricate materials with improved functionalities such as bactericidal capabilities.

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