4.7 Article

The Upper Respiratory Tract of Felids Is Highly Susceptible to SARS-CoV-2 Infection

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Otorhinolaryngology

ACE2 expression in allergic airway disease may decrease the risk and severity of COVID-19

Sunita Chhapola Shukla

Summary: The relationship between allergic airway diseases and COVID-19 risk is controversial, with current understanding suggesting it does not increase disease severity; timely asthma treatment may help reduce the risk of coronavirus infection.

EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY (2021)

Article Infectious Diseases

Culture of SARS-CoV-2 in a panel of laboratory cell lines, permissivity, and differences in growth profile

Nathalie Wurtz et al.

Summary: The study tested 4 locally isolated strains of SARS-CoV-2 on 34 cell lines commonly used for isolating human pathogenic microorganisms, finding that 7 cell lines were able to support virus replication. Results indicate that there are differences in cytopathogenic effects and multiplication abilities in cells with different strains.

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES (2021)

Article Respiratory System

ACE2 expression is elevated in airway epithelial cells from older and male healthy individuals but reduced in asthma

Peter A. B. Wark et al.

Summary: This study found that ACE2 gene expression is associated with age and gender, and is lower in asthma patients. The expression of some genes related to SARS-CoV-2 cell entry in asthma patients is also different from other populations.

RESPIROLOGY (2021)

Article Immunology

Susceptibility and Attenuated Transmissibility of SARS-CoV-2 in Domestic Cats

Linlin Bao et al.

Summary: Research has shown that domestic cats can be infected with SARS-CoV-2, but the virus's transmissibility is significantly attenuated after being passed between cats, likely due to variations in the amino acids of the receptor-binding domain sites of angiotensin-converting enzyme 2 between humans and cats. These findings provide insight into the transmissibility of SARS-CoV-2 in cats and offer important information for protecting the health of humans and cats.

JOURNAL OF INFECTIOUS DISEASES (2021)

Article Immunology

Key Components of Inflammasome and Pyroptosis Pathways Are Deficient in Canines and Felines, Possibly Affecting Their Response to SARS-CoV-2 Infection

Haoran Cui et al.

Summary: The comparative genomics study reveals differences in key components of the inflammasome and pyroptosis pathways among dogs, cats, and tigers, possibly contributing to milder symptoms. Cats and tigers lack AIM2 and NLRP1, while dogs lack AIM2 and encode a shorter form of NLRC4. Deficiencies in these pathways may provide an evolutionary advantage against SARS-CoV-2 by reducing cytokine storm-induced host damage.

FRONTIERS IN IMMUNOLOGY (2021)

Article Medicine, General & Internal

Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity

Markus Hoffmann et al.

Summary: The study demonstrates that Camostat mesylate and its metabolite GBPA can block the spread of SARS-CoV-2 in human lung tissue, and the related protease inhibitor Nafamostat mesylate exhibits enhanced antiviral activity.

EBIOMEDICINE (2021)

Article Multidisciplinary Sciences

COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets

Toni M. Delorey et al.

Summary: This study using single-cell and spatial atlases revealed the impact of COVID-19 infection on lung, kidney, liver, and heart tissues, showing structural remodeling and viral RNA enrichment. Differences in lung inflammatory responses and transcriptional alterations in heart tissue of COVID-19 patients were also identified, along with cell types and genes associated with disease severity.

NATURE (2021)

Article Virology

Vascular Inflammation Is Associated with Loss of Aquaporin 1 Expression on Endothelial Cells and Increased Fluid Leakage in SARS-CoV-2 Infected Golden Syrian Hamsters

Lisa Allnoch et al.

Summary: The study found that SARS-CoV-2 infection causes endothelial hypertrophy, endothelialitis, and vasculitis, with inflammation mainly consisting of macrophages and fewer T-lymphocytes and neutrophils/heterophils infiltrating vascular walls. Affected vessels exhibit edema formation associated with loss of aquaporin 1 on endothelial cells.

VIRUSES-BASEL (2021)

Article Immunology

Vasculitis and Neutrophil Extracellular Traps in Lungs of Golden Syrian Hamsters With SARS-CoV-2

Kathrin Becker et al.

Summary: Neutrophil extracellular traps (NETs) play a crucial role in severe COVID-19 cases, and the Syrian hamster model could serve as a useful tool to further investigate the impact of vascular lesions and NETs in the pathogenesis of COVID-19.

FRONTIERS IN IMMUNOLOGY (2021)

Article Immunology

Susceptibility of Well Differentiated Airway Epithelial Cell Cultures from Domestic and Wild Animals to Severe Acute Respiratory Syndrome Coronavirus 2

Mitra Gultom et al.

Summary: SARS-CoV-2 efficiently replicated in monkey and cat airway epithelial cell cultures, raising concerns about their potential role as reservoirs for the virus and highlighting the need for close surveillance.

EMERGING INFECTIOUS DISEASES (2021)

Article Multidisciplinary Sciences

Transmission of SARS-CoV-2 on mink farms between humans and mink and back to humans

Bas B. Oude Munnink et al.

Summary: Animal experiments have shown that various animals can be infected by SARS-CoV-2, with evidence of animal-to-human transmission within mink farms. Investigation into mink farm outbreaks revealed that the virus was initially introduced by humans and has since evolved, causing transmission between mink farms. Despite enhanced biosecurity measures and culling, transmission occurred between farms in three large clusters with unknown modes of transmission, resulting in a high percentage of infections among mink farm residents and employees.

SCIENCE (2021)

Article Multidisciplinary Sciences

A pneumonia outbreak associated with a new coronavirus of probable bat origin

Peng Zhou et al.

NATURE (2020)

Article Medicine, General & Internal

A Novel Coronavirus from Patients with Pneumonia in China, 2019

Na Zhu et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Letter Critical Care Medicine

Tobacco Smoking Increases the Lung Gene Expression of ACE2, the Receptor of SARS-CoV-2

Guoshuai Cai et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2020)

Correction Biochemistry & Molecular Biology

Probable Pangolin Origin of SARS-CoV-2 Associated with the COVID-19 Outbreak (vol 30, 1346.e1, 2020)

Tao Zhang et al.

CURRENT BIOLOGY (2020)

Article Allergy

Association of respiratory allergy, asthma, and expression of the SARS-CoV-2 receptor ACE2

Daniel J. Jackson et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2020)

Article Multidisciplinary Sciences

Cell entry mechanisms of SARS-CoV-2

Jian Shang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Multidisciplinary Sciences

Isolation of SARS-CoV-2-related coronavirus from Malayan pangolins

Kangpeng Xiao et al.

NATURE (2020)

Article Multidisciplinary Sciences

Identifying SARS-CoV-2-related coronaviruses in Malayan pangolins

Tommy Tsan-Yuk Lam et al.

NATURE (2020)

Article Multidisciplinary Sciences

Infection of dogs with SARS-CoV-2

Thomas H. C. Sit et al.

NATURE (2020)

Article Biochemistry & Molecular Biology

SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes

Waradon Sungnak et al.

NATURE MEDICINE (2020)

Letter Medicine, General & Internal

Transmission of SARS-CoV-2 in Domestic Cats

Peter J. Halfmann et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Article Infectious Diseases

SARS-CoV-2 infection in farmed minks, the Netherlands, April and May 2020

Nadia Oreshkova et al.

EUROSURVEILLANCE (2020)

Article Multidisciplinary Sciences

Experimental infection of domestic dogs and cats with SARS-CoV-2: Pathogenesis, transmission, and response to reexposure in cats

Angela M. Bosco-Lauth et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Multidisciplinary Sciences

Structural and functional modelling of SARS-CoV-2 entry in animal models

Greg N. Brooke et al.

SCIENTIFIC REPORTS (2020)

Letter Immunology

SARS-CoV-2 Natural Transmission from Human to Cat, Belgium, March 2020

Mutien Garigliany et al.

EMERGING INFECTIOUS DISEASES (2020)

Letter Medicine, General & Internal

Multiorgan and Renal Tropism of SARS-CoV-2

Victor G. Puelles et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Article Immunology

A serological survey of SARS-CoV-2 in cat in Wuhan

Qiang Zhang et al.

EMERGING MICROBES & INFECTIONS (2020)

Article Immunology

SARS-CoV-2 infection, disease and transmission in domestic cats

Natasha N. Gaudreault et al.

EMERGING MICROBES & INFECTIONS (2020)

Article Biochemical Research Methods

Paramyxovirus Infections in Ex Vivo Lung Slice Cultures of Different Host Species

Rory D. de Vries et al.

METHODS AND PROTOCOLS (2018)

Article Veterinary Sciences

Expression of feline angiotensin converting enzyme 2 and its interaction with SARS-CoV S1 protein

Hongyan Guo et al.

RESEARCH IN VETERINARY SCIENCE (2008)