4.7 Review

Flubendazole Plays an Important Anti-Tumor Role in Different Types of Cancers

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Nanoscience & Nanotechnology

A nanotherapeutic strategy to overcome chemotherapeutic resistance of cancer stem-like cells

Shiyang Shen et al.

Summary: This study presents a nanoparticle-based strategy for killing CSCs in tumors by inducing CSC differentiation with all-trans retinoic acid release under hypoxic conditions and triggering cell death with camptothecin release in response to increasing reactive oxygen species levels in differentiating CSCs.

NATURE NANOTECHNOLOGY (2021)

Article Pharmacology & Pharmacy

Flubendazole, FDA-approved anthelmintic, elicits valid antitumor effects by targeting P53 and promoting ferroptosis in castration-resistant prostate cancer

Xumin Zhou et al.

Summary: Flubendazole has potential inhibitory effects on castration-resistant prostate cancer, exerting anti-cancer effects by hindering the cell cycle and activating ferroptosis, and showing synergistic effects with 5-fluorouracil in chemotherapy.

PHARMACOLOGICAL RESEARCH (2021)

Article Pharmacology & Pharmacy

Tamoxifen overcomes the trastuzumab-resistance of SK-BR-3 tumorspheres by targeting crosstalk between cytoplasmic estrogen receptor a and the EGFR/HER2 signaling pathway

Yun-Suk Kwon et al.

Summary: This study investigated the mechanism underlying trastuzumab resistance in a quiescent cell population and found that the crosstalk between cytoplasmic ERa and the HER2/EGFR signaling pathway is a novel therapeutic target for HER2-positive breast cancer. Combination therapy of tamoxifen and trastuzumab may overcome trastuzumab resistance in HER2-positive breast cancer patients, providing a new treatment strategy.

BIOCHEMICAL PHARMACOLOGY (2021)

Review Oncology

Mechanisms of resistance to trastuzumab emtansine (T-DM1) in HER2-positive breast cancer

Francis W. Hunter et al.

BRITISH JOURNAL OF CANCER (2020)

Article Oncology

Cancer statistics, 2020

Rebecca L. Siegel et al.

CA-A CANCER JOURNAL FOR CLINICIANS (2020)

Article Genetics & Heredity

p53 regulates its own expression by an intrinsic exoribonuclease activity through AU-rich elements

Sanaz Derech-Haim et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2020)

Review Medicine, General & Internal

Whipworm and roundworm infections

Kathryn J. Else et al.

NATURE REVIEWS DISEASE PRIMERS (2020)

Review Immunology

Breast cancer: Biology, biomarkers, and treatments

Khadijeh Barzaman et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2020)

Article Medicine, Research & Experimental

Targeting tumor-associated macrophages and granulocytic myeloid-derived suppressor cells augments PD-1 blockade in cholangiocarcinoma

Emilien Loeuillard et al.

JOURNAL OF CLINICAL INVESTIGATION (2020)

Review Medicine, Research & Experimental

Treatment of Advanced Prostate Cancer

Min Yuen Teo et al.

ANNUAL REVIEW OF MEDICINE, VOL 70 (2019)

Review Oncology

The evolving role of diet in prostate cancer risk and progression

Adeel Kaiser et al.

CURRENT OPINION IN ONCOLOGY (2019)

Article Oncology

Flubendazole demonstrates valid antitumor effects by inhibiting STAT3 and activating autophagy

Shichong Lin et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)

Article Oncology

ACLY facilitates colon cancer cell metastasis by CTNNB1

Jun Wen et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)

Review Nursing

Surgical Treatment of Lung Cancer

Haley Hoy et al.

CRITICAL CARE NURSING CLINICS OF NORTH AMERICA (2019)

Article Medicine, General & Internal

Breast cancer

Nadia Harbeck et al.

NATURE REVIEWS DISEASE PRIMERS (2019)

Article Medicine, General & Internal

Trastuzumab Emtansine for Residual Invasive HER2-Positive Breast Cancer

G. von Minckwitz et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

Article Infectious Diseases

Flubendazole as a macrofilaricide: History and background

Timothy G. Geary et al.

PLOS NEGLECTED TROPICAL DISEASES (2019)

Review Cell Biology

Understanding p53 functions through p53 antibodies

Kanaga Sabapathy et al.

JOURNAL OF MOLECULAR CELL BIOLOGY (2019)

Review Urology & Nephrology

Current treatment strategies for advanced prostate cancer

Kazumasa Komura et al.

INTERNATIONAL JOURNAL OF UROLOGY (2018)

Article Biochemistry & Molecular Biology

Inhibition of JAK2/STAT3 reduces tumor-induced angiogenesis and myeloid-derived suppressor cells in head and neck cancer

Jian-Feng Liu et al.

MOLECULAR CARCINOGENESIS (2018)

Article Biochemical Research Methods

The metabolism of flubendazole in human liver and cancer cell lines

Lucie Raisova Stuchlikova et al.

DRUG TESTING AND ANALYSIS (2018)

Article Pharmacology & Pharmacy

Dual inhibition of STAT1 and STAT3 activation downregulates expression of PD-L1 in human breast cancer cells

Varun Sasidharan Nair et al.

EXPERT OPINION ON THERAPEUTIC TARGETS (2018)

Review Pathology

Epithelial Mesenchymal Transition in Tumor Metastasis

Vivek Mittal

ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 13 (2018)

Article Toxicology

Flubendazole induces mitotic catastrophe and apoptosis in melanoma cells

K. Canova et al.

TOXICOLOGY IN VITRO (2018)

Article Biochemistry & Molecular Biology

Flubendazole and mebendazole impair migration and epithelial to mesenchymal transition in oral cell lines

Vera Kralova et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2018)

Article Oncology

Breast cancer stem cells: Features, key drivers and treatment options

Juergen Dittmer

SEMINARS IN CANCER BIOLOGY (2018)

Article Dermatology

Adjuvant therapy for resected high-risk melanoma

Justin C. Moser et al.

SEMINARS IN CUTANEOUS MEDICINE AND SURGERY (2018)

Article Oncology

The Effect of Flubendazole on Adhesion and Migration in SW480 and SW620 Colon Cancer Cells

Veronika Hanusova et al.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2018)

Article Medicine, General & Internal

HER2-positive breast cancer

Sibylle Loibl et al.

LANCET (2017)

Review Parasitology

Benzimidazole resistance in helminths: From problem to diagnosis

Luis Fernando et al.

ACTA TROPICA (2016)

Review Oncology

Perspectives of Benzimidazole Derivatives as Anticancer Agents in the New Era

Snehlata Yadav et al.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2016)

Article Pharmacology & Pharmacy

Flubendazole induces mitotic catastrophe and senescence in colon cancer cells in vitro

Vera Kralova et al.

JOURNAL OF PHARMACY AND PHARMACOLOGY (2016)

Article Oncology

Global Cancer Statistics, 2012

Lindsey A. Torre et al.

CA-A CANCER JOURNAL FOR CLINICIANS (2015)

Article Oncology

Potential Anti-cancer Drugs Commonly Used for Other Indications

Veronika Hanusova et al.

CURRENT CANCER DRUG TARGETS (2015)

Review Pharmacology & Pharmacy

Targeted Therapies for Triple-Negative Breast Cancer: Combating a Stubborn Disease

Murugan Kalimutho et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2015)

Article Multidisciplinary Sciences

Identification of flubendazole as potential anti-neuroblastoma compound in a large cell line screen

Martin Michaelis et al.

SCIENTIFIC REPORTS (2015)

Article Dermatology

Cutaneous Malignant Melanoma: Update on Diagnostic and Prognostic Biomarkers

Ossama Abbas et al.

AMERICAN JOURNAL OF DERMATOPATHOLOGY (2014)

Review Oncology

Treatment of HER2-positive breast cancer

Maria Cristina Figueroa-Magalhaes et al.

BREAST (2014)

Article Psychiatry

A review of clinical aspects of breast cancer

Shai Libson et al.

INTERNATIONAL REVIEW OF PSYCHIATRY (2014)

Article Multidisciplinary Sciences

Comprehensive molecular portraits of human breast tumours

Daniel C. Koboldt et al.

NATURE (2012)

Article Medicine, General & Internal

Non-Small Cell Lung Cancer: Epidemiology, Risk Factors, Treatment, and Survivorship

Julian R. Molina et al.

MAYO CLINIC PROCEEDINGS (2012)

Editorial Material Infectious Diseases

Flubendazole: a candidate macrofilaricide for lymphatic filariasis and onchocerciasis field programs

Charles D. Mackenzie et al.

EXPERT REVIEW OF ANTI-INFECTIVE THERAPY (2011)

Editorial Material Environmental Sciences

Prostate Cancer

Scott Eggener

THESCIENTIFICWORLDJOURNAL (2011)

Review Oncology

Colon cancer

Roberto Labianca et al.

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2010)

Article Radiology, Nuclear Medicine & Medical Imaging

Triple-negative breast cancer: correlation between imaging and pathological findings

Eun Sook Ko et al.

EUROPEAN RADIOLOGY (2010)

Review Oncology

Microtubule dynamics as a target in oncology

April L. Risinger et al.

CANCER TREATMENT REVIEWS (2009)

Article Biochemistry & Molecular Biology

Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening

Piyush B. Gupta et al.

Article Pharmacology & Pharmacy

Microtubule Binding and Disruption and Induction of Premature Senescence by Disorazole C1

Marni Brisson Tierno et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2009)

Review Genetics & Heredity

Melanoma Biomarkers Current Status and Utility in Diagnosis, Prognosis, and Response to Therapy

Nikolas K. Haass et al.

MOLECULAR DIAGNOSIS & THERAPY (2009)

Review Biotechnology & Applied Microbiology

Tumour-initiating cells: challenges and opportunities for anticancer drug discovery

Bin-Bing S. Zhou et al.

NATURE REVIEWS DRUG DISCOVERY (2009)

Article Parasitology

Flubendazole in cystic echinococcosis therapy: Pharmaco-parasitological evaluation in mice

Laura Ceballos et al.

PARASITOLOGY INTERNATIONAL (2009)

Article Oncology

Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy

Xiaoxian Li et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2008)

Article Biochemistry & Molecular Biology

TMEM166, a novel transmembrane protein, regulates cell autophagy and apoptosis

Lan Wang et al.

APOPTOSIS (2007)

Article Oncology

Cancer statistics, 2007

Ahmedin Jemal et al.

CA-A CANCER JOURNAL FOR CLINICIANS (2007)

Article Oncology

The response of CD24-/low/CD44+ breast cancer-initiating cells to radiation

Tiffany M. Phillips et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2006)

Article Multidisciplinary Sciences

System for quantifying dynamic protein interactions defines a role for Herceptin in modulating ErbB2 interactions

T. S. Wehrman et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Review Oncology

Microtubules as a target for anticancer drugs

MA Jordan et al.

NATURE REVIEWS CANCER (2004)

Review Cell Biology

Post-translational modifications regulate microtubule function

S Westermann et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)

Article Biochemistry & Molecular Biology

Multiple lethal effects induced by a benzimidazole anthelmintic in the anterior intestine of the nematode Haemonchus contortus

DP Jasmer et al.

MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2000)