Flubendazole Plays an Important Anti-Tumor Role in Different Types of Cancers

Flubendazole, belonging to benzimidazole, is a broad-spectrum insect repellent and has been repurposed as a promising anticancer drug. In recent years, many studies have shown that flubendazole plays an anti-tumor role in different types of cancers, including breast cancer, melanoma, prostate cancer, colorectal cancer, and lung cancer. Although the anti-tumor mechanism of flubendazole has been studied, it has not been fully understood. In this review, we summarized the recent studies regarding the anti-tumor effects of flubendazole in different types of cancers and analyzed the related mechanisms, in order to provide the theoretical reference for further studies in the future.

Automated summary

Flubendazole, a broad-spectrum insect repellent, has been repurposed as a promising anticancer drug. Recent studies have shown its anti-tumor effects in different types of cancers, but the underlying mechanisms are not fully understood. This review summarizes the latest research on the anti-tumor effects of flubendazole in different types of cancers and analyzes the related mechanisms for future studies.