相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。The Effect of Metformin on Male Reproductive Function and Prostate: An Updated Review
Chin-Hsiao Tseng
WORLD JOURNAL OF MENS HEALTH (2022)
Umbelliferone ameliorates oxidative stress and testicular injury, improves steroidogenesis and upregulates peroxisome proliferator-activated receptor gamma in type 2 diabetic rats
Mohamed A. M. Allam et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2022)
Obesity and male infertility: Mechanisms and management
Kristian Leisegang et al.
ANDROLOGIA (2021)
Constitutively Activating Mutants of Equine LH/CGR Constitutively Induce Signal Transduction and Inactivating Mutations Impair Biological Activity and Cell-Surface Receptor Loss In Vitro
Munkhzaya Byambaragchaa et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Improvement Effect of Metformin on Female and Male Reproduction in Endocrine Pathologies and Its Mechanisms
Alexander O. Shpakov
PHARMACEUTICALS (2021)
Diabetes Type 1 Negatively Influences Leydig Cell Function in Rats, Which is Partially Reversible By Insulin Treatment
Isabel Viola Wagner et al.
ENDOCRINOLOGY (2021)
PKA and AMPK Signaling Pathways Differentially Regulate Luteal Steroidogenesis
Emilia Przygrodzka et al.
ENDOCRINOLOGY (2021)
Role of Constitutive STAR in Leydig Cells
Melanie Galano et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Energy sensors and reproductive hypothalamo-pituitary ovarian axis (HPO) in female mammals: Role of mTOR (mammalian target of rapamycin), AMPK (AMP-activated protein kinase) and SIRT1 (Sirtuin 1)
Anthony Estienne et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2021)
The Current and Potential Therapeutic Use of Metformin-The Good Old Drug
Jozef Drzewoski et al.
PHARMACEUTICALS (2021)
Impact of metabolic syndrome on the viability of human spermatozoa: a cross-sectional descriptive study in men from infertile couples
Minh Tam Le et al.
BASIC AND CLINICAL ANDROLOGY (2021)
Bee bread mitigates downregulation of steroidogenic genes, decreased spermatogenesis, and epididymal oxidative stress in male rats fed with high-fat diet
Joseph Bagi Suleiman et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2021)
Metformin in Pregnancy for Women with Type 2 Diabetes: a Review
Jamie L. Benham et al.
CURRENT DIABETES REPORTS (2021)
Diagnosis and Management of Infertility A Review
Sandra Ann Carson et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)
Safflower seed oil improves steroidogenesis and spermatogenesis in rats with type II diabetes mellitus by modulating the genes expression involved in steroidogenesis, inflammation and oxidative stress
Khadijeh Nasiri et al.
JOURNAL OF ETHNOPHARMACOLOGY (2021)
Cardamonin exerts a protective effect against autophagy and apoptosis in the testicles of diabetic male rats through the expression of Nrf2 via p62-mediated Keap-1 degradation
Shereen M. Samir et al.
KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY (2021)
Review Metformin in cardiovascular diabetology: a focused review of its on endothelial function
Yu Ding et al.
THERANOSTICS (2021)
Diabetes-induced testicular oxidative stress, inflammation, and caspase-dependent apoptosis: the protective role of metformin
Victor Udo Nna et al.
ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY (2020)
Malaysian propolis and metformin mitigate subfertility in streptozotocin-induced diabetic male rats by targeting steroidogenesis, testicular lactate transport, spermatogenesis and mating behaviour
Victor Udo Nna et al.
ANDROLOGY (2020)
Evaluation of carvacrol on pituitary and sexual hormones and their receptors in the testicle of male diabetic rats
H. Shoorei et al.
HUMAN & EXPERIMENTAL TOXICOLOGY (2020)
Effect of metformin on testicular expression and localization of leptin receptor and levels of leptin in the diabetic mice
Lalrawngbawli Annie et al.
MOLECULAR REPRODUCTION AND DEVELOPMENT (2020)
Testosterone, Spermatogenesis, and Unravelling the Mysteries of Puberty
David J. Handelsman
ENDOCRINOLOGY (2020)
The effect of metformin treatment on the basal and gonadotropin-stimulated steroidogenesis in male rats with type 2 diabetes mellitus
Kira V. Derkach et al.
ANDROLOGIA (2020)
Metformin attenuates steroidogenesis in ovarian follicles of the broiler breeder hen
Evelyn A. Weaver et al.
REPRODUCTION (2020)
Metformin Ameliorates Testicular Function and Spermatogenesis in Male Mice with High-Fat and High-Cholesterol Diet-Induced Obesity
Chin-Yu Liu et al.
NUTRIENTS (2020)
Comparative Study of the Steroidogenic Effects of Human Chorionic Gonadotropin and Thieno[2,3-D]pyrimidine-Based Allosteric Agonist of Luteinizing Hormone Receptor in Young Adult, Aging and Diabetic Male Rats
Andrey A. Bakhtyukov et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Impact of metabolic syndrome on sex hormones and reproductive function: a meta-analysis of 2923 cases and 14062 controls
Lihong Zhou et al.
Aging-US (2020)
The evidence of metabolic-improving effect of metformin in Ay/a mice with genetically-induced melanocortin obesity and the contribution of hypothalamic mechanisms to this effect
Kira Derkach et al.
PLOS ONE (2019)
Analysis of equilibrium binding of an orthosteric tracer and two allosteric modulators
Jan Jakubik et al.
PLOS ONE (2019)
Mechanisms of action of metformin with special reference to cardiovascular protection
Alexey V. Zilov et al.
DIABETES-METABOLISM RESEARCH AND REVIEWS (2019)
Development and full validation of an HPLC methodology to quantify atorvastatin and curcumin after their intranasal co-delivery to mice
Jessica Silva et al.
BIOMEDICAL CHROMATOGRAPHY (2019)
Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus
Marc Foretz et al.
NATURE REVIEWS ENDOCRINOLOGY (2019)
The protective effect of Stevia rebaudiana Bertoni on serum hormone levels, key steroidogenesis enzymes, and testicular damage in testes of diabetic rats
Fatemeh Gholizadeh et al.
ACTA HISTOCHEMICA (2019)
Oxidative Stress, NF-κB-Mediated Inflammation and Apoptosis in the Testes of Streptozotocin-Induced Diabetic Rats: Combined Protective Effects of Malaysian Propolis and Metformin
Victor Udo Nna et al.
ANTIOXIDANTS (2019)
Down-regulation of steroidogenesis-related genes and its accompanying fertility decline in streptozotocin-induced diabetic male rats: ameliorative effect of metformin
V. U. Nna et al.
ANDROLOGY (2019)
A Low Molecular Weight Agonist of the Luteinizing Hormone Receptor Stimulates Adenylyl Cyclase in the Testicular Membranes and Steroidogenesis in the Testes of Rats with Type 1 Diabetes
A. A. Bakhtyukov et al.
BIOCHEMISTRY MOSCOW SUPPLEMENT SERIES A-MEMBRANE AND CELL BIOLOGY (2019)
Decrease in the Basal and Luteinizing Hormone Receptor Agonist-Stimulated Testosterone Production in Aging Male Rats
A. A. Bakhtyukov et al.
ADVANCES IN GERONTOLOGY (2019)
Metformin for prevention or delay of type 2 diabetes mellitus and its associated complications in persons at increased risk for the development of type 2 diabetes mellitus
Kasper S. Madsen et al.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2019)
Diabetes-induced hyperglycemia impairs male reproductive function: a systematic review
Constanze C. Maresch et al.
HUMAN REPRODUCTION UPDATE (2018)
Leydig cells: formation, function, and regulation
Barry R. Zirkin et al.
BIOLOGY OF REPRODUCTION (2018)
Two Hormones for One Receptor: Evolution, Biochemistry, Actions, and Pathophysiology of LH and hCG
Livio Casarini et al.
ENDOCRINE REVIEWS (2018)
MECHANISMS IN ENDOCRINOLOGY Hormonal regulation of spermatogenesis: mutant mice challenging old paradigms
Ilpo Huhtaniemi
EUROPEAN JOURNAL OF ENDOCRINOLOGY (2018)
Metformin in Pregnancy: Mechanisms and Clinical Applications
Steve Hyer et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
An attempt to characterize the human Chorionic Gonadotropin protein by reversed phase liquid chromatography coupled with high-resolution mass spectrometry at the intact level
Julien Camperi et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2018)
Potential application of testosterone replacement therapy as treatment for obesity and type 2 diabetes in men
Julius Fink et al.
STEROIDS (2018)
Curcumin Attenuates Testicular Injury in Rats with Streptozotocin-Induced Diabetes
Wenliang Zha et al.
BIOMED RESEARCH INTERNATIONAL (2018)
Metformin in Reproductive Biology
Melanie Faure et al.
FRONTIERS IN ENDOCRINOLOGY (2018)
Systematic review of hormone replacement therapy in the infertile man
Amr El Meliegy et al.
ARAB JOURNAL OF UROLOGY (2018)
Effect of metformin on germ cell-specific apoptosis, oxidative stress and epididymal sperm quality after testicular torsion/detorsion in rats
M. Ghasemnejad-Berenji et al.
ANDROLOGIA (2018)
Renoprotective Effects of Metformin
Marc E. De Broe et al.
NEPHRON (2018)
Clomiphene citrate effect in obese men with low serum testosterone treated with metformin due to dysmetabolic disorders: A randomized, double-blind, placebo-controlled study
Carla Pelusi et al.
PLOS ONE (2017)
Human LH and hCG stimulate differently the early signalling pathways but result in equal testosterone synthesis in mouse Leydig cells in vitro
Laura Riccetti et al.
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY (2017)
Human Luteinizing Hormone and Chorionic Gonadotropin Display Biased Agonism at the LH and LH/CG Receptors
Laura Riccetti et al.
SCIENTIFIC REPORTS (2017)
Steroidogenesis in Leydig cells: effects of aging and environmental factors
Yiyan Wang et al.
REPRODUCTION (2017)
Metformin therapy for the reproductive and metabolic consequences of polycystic ovary syndrome
Susan Sam et al.
DIABETOLOGIA (2017)
Metformin: clinical use in type 2 diabetes
Elizabeth Sanchez-Rangel et al.
DIABETOLOGIA (2017)
The mechanisms of action of metformin
Graham Rena et al.
DIABETOLOGIA (2017)
Current understanding of metformin effect on the control of hyperglycemia in diabetes
Hongying An et al.
JOURNAL OF ENDOCRINOLOGY (2016)
Erectile Dysfunction and Low Sex Drive in Men with Type 2 DM: The Potential Role of Diabetic Pharmacotherapy
Hayder M. Al-Kuraishy et al.
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH (2016)
In Vitro and In Vivo Studies of Functional Activity of New Low Molecular Weight Agonists of the Luteinizing Hormone Receptor
K. V. Derkach et al.
BIOCHEMISTRY MOSCOW SUPPLEMENT SERIES A-MEMBRANE AND CELL BIOLOGY (2016)
The effects of diabetes on male fertility and epigenetic regulation during spermatogenesis
Guo-Lian Ding et al.
ASIAN JOURNAL OF ANDROLOGY (2015)
Leydig cell aging and hypogonadism
M. C. Beattie et al.
EXPERIMENTAL GERONTOLOGY (2015)
Testosterone deficiency induced by progressive stages of diabetes mellitus impairs glucose metabolism and favors glycogenesis in mature rat Sertoli cells
Luis Rato et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2015)
Protective effects of metformin on reproductive function in obese male rats induced by high-fat diet
Wen-jie Yan et al.
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS (2015)
The Effect of Long-Term Intranasal Serotonin Treatment on Metabolic Parameters and Hormonal Signaling in Rats with High-Fat Diet/Low-Dose Streptozotocin-Induced Type 2 Diabetes
Kira V. Derkach et al.
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (2015)
AMPK: a master energy regulator for gonadal function
Michael J. Bertoldo et al.
FRONTIERS IN NEUROSCIENCE (2015)
Effect of metformin therapy and dietary supplements on semen parameters in hyperinsulinaemic males
E. Bosman et al.
ANDROLOGIA (2015)
How does obesity affect fertility in men - and what are the treatment options?
Victoria J. Stokes et al.
CLINICAL ENDOCRINOLOGY (2015)
Metformin and male reproduction: effects on Sertoli cell metabolism
M. G. Alves et al.
BRITISH JOURNAL OF PHARMACOLOGY (2014)
Metformin: From Mechanisms of Action to Therapies
Marc Foretz et al.
CELL METABOLISM (2014)
The stimulating influence of thienopyrimidine compounds on the adenylyl cyclase signaling systems in the rat testes
A. O. Shpakov et al.
DOKLADY BIOCHEMISTRY AND BIOPHYSICS (2014)
Human Granulosa Cells: Insulin and insulin-Like Growth Factor-1 Receptors and Aromatase Expression Modulation by Metformin
Isabela Piva Fuhrmeister et al.
GYNECOLOGIC AND OBSTETRIC INVESTIGATION (2014)
Long-Term Metformin Usage and Cognitive Function among Older Adults with Diabetes
Tze Pin Ng et al.
JOURNAL OF ALZHEIMERS DISEASE (2014)
A review of luteinising hormone and human chorionic gonadotropin when used in assisted reproductive technology
Diego Ezcurra et al.
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY (2014)
The regulation of spermatogenesis by androgens
Lee B. Smith et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2014)
Diabetes Mellitus Induced Impairment of Male Reproductive Functions: A Review
Ram Niwas Jangir et al.
CURRENT DIABETES REVIEWS (2014)
hCG-induced endoplasmic reticulum stress triggers apoptosis and reduces steroidogenic enzyme expression through activating transcription factor 6 in Leydig cells of the testis
Sun-Ji Park et al.
JOURNAL OF MOLECULAR ENDOCRINOLOGY (2013)
Prevalence of low testosterone levels in men with type 2 diabetes mellitus: a cross-sectional study
Ayman A. Al Hayek et al.
JOURNAL OF FAMILY AND COMMUNITY MEDICINE (2013)
Gonadotropin Resistance
Ana Claudia Latronico et al.
HORMONE RESISTANCE AND HYPERSENSITIVITY: FROM GENETICS TO CLINICAL MANAGEMENT (2013)
Dynamic testosterone responses to near-physiological LH pulses are determined by the time pattern of prior intravenous LH infusion
Johannes D. Veldhuis et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2012)
The effect of metformin on food intake and its potential role in hypothalamic regulation in obese diabetic rats
Wen-shan Lv et al.
BRAIN RESEARCH (2012)
Metformin Improves Pregnancy and Live-Birth Rates in Women with Polycystic Ovary Syndrome (PCOS): A Multicenter, Double-Blind, Placebo-Controlled Randomized Trial
Laure Morin-Papunen et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2012)
LH and hCG Action on the Same Receptor Results in Quantitatively and Qualitatively Different Intracellular Signalling
Livio Casarini et al.
PLOS ONE (2012)
Prevention of the Onset of Ovarian Hyperstimulation Syndrome (OHSS) in the Rat After Ovulation Induction with a Low Molecular Weight Agonist of the LH Receptor Compared with hCG and rec-LH
Ruud van de Lagemaat et al.
ENDOCRINOLOGY (2011)
Metformin improves semen characteristics of oligo-terato-asthenozoospermic men with metabolic syndrome
Giuseppe Morgante et al.
FERTILITY AND STERILITY (2011)
Incidence of Dementia is Increased in Type 2 Diabetes and Reduced by the Use of Sulfonylureas and Metformin
Chih-Cheng Hsu et al.
JOURNAL OF ALZHEIMERS DISEASE (2011)
Low Testosterone in Men with Type 2 Diabetes: Significance and Treatment
Mathis Grossmann
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2011)
Non-classical actions of testosterone and spermatogenesis
William H. Walker
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2010)
Metformin Inhibits Aromatase via an Extracellular Signal-Regulated Kinase-Mediated Pathway
Suman Rice et al.
ENDOCRINOLOGY (2009)
Induction of ovulation by a potent, orally active, low molecular weight agonist (Org 43553) of the luteinizing hormone receptor
R. van de Lagemaat et al.
HUMAN REPRODUCTION (2009)
Stimulation of Lactate Production in Human Granulosa Cells by Metformin and Potential Involvement of Adenosine 5′ Monophosphate-Activated Protein Kinase
Malcolm C. Richardson et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2009)
The differential regulation of steroidogenic acute regulatory protein-mediated steroidogenesis by type I and type II PKA in MA-10 cells
Matthew T. Dyson et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2009)
Activation of PPAR gamma by Rosiglitazone Does Not Negatively Impact Male Sex Steroid Hormones in Diabetic Rats
Mahmoud Mansour et al.
PPAR RESEARCH (2009)
Testosterone Concentration in Young Patients With Diabetes
Anil Chandel et al.
DIABETES CARE (2008)
Evaluation of endocrine testing of Leydig cell function using extractive and recombinant human chorionic gonadotropin and different doses of recombinant human LH in normal men
Anne Cailleux-Bounacer et al.
EUROPEAN JOURNAL OF ENDOCRINOLOGY (2008)
Serum 17-hydroxyprogesterone strongly correlates with intratesticular testosterone in gonadotropin-suppressed normal men receiving various dosages of human chorionic gonadotropin
John K. Amory et al.
FERTILITY AND STERILITY (2008)
Low testosterone levels are common and associated with insulin resistance in men with diabetes
Mathis Grossmann et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2008)
Hormonal regulation of testicular steroid and cholesterol homeostasis
Stephen M. Eacker et al.
MOLECULAR ENDOCRINOLOGY (2008)
Analyzing real-time PCR data by the comparative C-T method
Thomas D. Schmittgen et al.
NATURE PROTOCOLS (2008)
A signaling-selective, nanomolar potent allosteric low molecular weight agonist for the human luteinizing hormone receptor
Chris J. van Koppen et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2008)
hCG treatment raises H2O2 levels and induces germ cell apoptosis in rat testis
Dinesh K. Gautam et al.
APOPTOSIS (2007)
Clinical and biochemical assessment of hypogonadism in men with type 2 diabetes: Correlations with bioavailable testosterone and visceral adiposity
Dheeraj Kapoor et al.
DIABETES CARE (2007)
Effects of metformin on bovine granulosa cells steroidogenesis:: Possible involvement of adenosine 5′ monophosphate-activated protein kinase (AMPK)
Lucie Tosca et al.
BIOLOGY OF REPRODUCTION (2007)
Effect of body weight on testosterone/estradiol ratio in oligozoospermic patients
I Fejes et al.
ARCHIVES OF ANDROLOGY (2006)
Regulation of luteinizing hormone/chorionic gonadotropin receptor messenger ribonucleic acid expression in the rat ovary: Relationship to cholesterol metabolism
L Wang et al.
ENDOCRINOLOGY (2005)
Blood pressure and cardiac autonomic nervous system in obese type 2 diabetic patients: Effect of metformin administration
D Manzella et al.
AMERICAN JOURNAL OF HYPERTENSION (2004)
Mechanisms of gonadotropin desensitization
A Amsterdam et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2002)
Ribavirin-induced sperm shape abnormalities in Wistar rat
K Narayana et al.
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS (2002)
The effects of metformin and diet on plasma testosterone and leptin levels in obese men
M Ozata et al.
OBESITY RESEARCH (2001)
Metformin directly inhibits androgen production in human thecal cells
GR Attia et al.
FERTILITY AND STERILITY (2001)