4.7 Article

Fucoxanthin Prevents Pancreatic Tumorigenesis in C57BL/6J Mice That Received Allogenic and Orthotopic Transplants of Cancer Cells

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Suppression of C-C chemokine receptor 1 is a key regulation for colon cancer chemoprevention in AOM/DSS mice by fucoxanthin

Masaru Terasaki et al.

Summary: The study demonstrated the potential cancer chemopreventive functions of Fucoxanthin in a murine colorectal adenocarcinoma model, showing significant effects on multiple cancer-associated signals, particularly through modulation of CCR1 expression.

JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2022)

Article Oncology

Alteration of fecal microbiota by fucoxanthin results in prevention of colorectal cancer in AOM/DSS mice

Masaru Terasaki et al.

Summary: Fucoxanthin has been shown to have anticancer properties in a mouse model of inflammation-associated colorectal cancer, with alterations in the gut microbiota playing a potentially key role in its chemopreventive effect.

CARCINOGENESIS (2021)

Article Oncology

Cancer Statistics, 2021

Rebecca L. Siegel et al.

Summary: Every year, the American Cancer Society projects the numbers of new cancer cases and deaths in the United States, with the latest data showing a significant decline in lung cancer mortality, while prostate cancer mortality has plateaued and breast and colorectal cancer mortality have slowed. Improvements in treatment have accelerated progress against lung cancer, leading to a record drop in overall cancer mortality.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

Article Oncology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Hyuna Sung et al.

Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

Article Oncology

Fucoxanthinol Induces Apoptosis in a Pancreatic Intraepithelial Neoplasia Cell Line

Masaru Terasaki et al.

Summary: The study demonstrated that Fucoxanthinol (FxOH) can inhibit cell proliferation in a pancreatic cancer cell line by arresting cells at S phase and suppressing the expression of various gene sets, including cytokine-cytokine receptor interaction and cell adhesion molecule CAMS. This suggests that FxOH may have potential in preventing pancreatic cancer development in murine cancer models.

CANCER GENOMICS & PROTEOMICS (2021)

Review Oncology

Fucoxanthin and Colorectal Cancer Prevention

Masaru Terasaki et al.

Summary: Fucoxanthin (Fx), found in edible brown algae, has been shown to have anticancer potential by improving colorectal cancer (CRC) and certain risk factors through various molecular mechanisms. It is suggested that dietary intervention with Fx and brown algae may contribute to reducing the risk of human CRC.

CANCERS (2021)

Article Medicine, General & Internal

Estimated Projection of US Cancer Incidence and Death to 2040

Lola Rahib et al.

Summary: This cross-sectional study projected cancer incidences and deaths in the United States up to 2040. The findings indicate significant changes in the most common cancers by 2040, with breast cancer projected to become the most common cancer and lung cancer remaining the leading cause of cancer-related death.

JAMA NETWORK OPEN (2021)

Review Oncology

The role of microbiome in pancreatic cancer

Jenny Jing Li et al.

Summary: Recent studies have revealed the significant impact of the microbiome on cancer development and treatment, especially in pancreatic ductal adenocarcinoma. Utilizing microbiome analyses can lead to the development of new diagnostic and therapeutic strategies, such as fecal microbiota transplantation, probiotics, and dietary changes.

CANCER AND METASTASIS REVIEWS (2021)

Article Oncology

Effect of Fucoxanthinol on Pancreatic Ductal Adenocarcinoma Cells from an N-Nitrosobis(2-oxopropyl)amine-initiated Syrian Golden Hamster Pancreatic Carcinogenesis Model

Masaru Terasaki et al.

Summary: This study showed that FxOH has a significant inhibitory effect on certain pancreatic cancer cells by regulating cell cycle and multiple signaling pathways.

CANCER GENOMICS & PROTEOMICS (2021)

Article Pharmacology & Pharmacy

Skin Irritation Testing beyond Tissue Viability: Fucoxanthin Effects on Inflammation, Homeostasis, and Metabolism

Renata Spagolla Napoleao Tavares et al.

PHARMACEUTICS (2020)

Article Biochemistry & Molecular Biology

Friend or Foe: Prognostic and Immunotherapy Roles of BTLA in Colorectal Cancer

Jingjing Song et al.

FRONTIERS IN MOLECULAR BIOSCIENCES (2020)

Article Oncology

BTLA blockade enhances Cancer therapy by inhibiting IL-6/IL-10-induced CD19high B lymphocytes

Yu-Li Chen et al.

JOURNAL FOR IMMUNOTHERAPY OF CANCER (2019)

Article Gastroenterology & Hepatology

Stratification of Pancreatic Ductal Adenocarcinomas Based on Tumor and Microenvironment Features

Francesco Puleo et al.

GASTROENTEROLOGY (2018)

Article Biotechnology & Applied Microbiology

Increased BTLA and HVEM in gastric cancer are associated with progression and poor prognosis

Xiuwen Lan et al.

ONCOTARGETS AND THERAPY (2017)

Review Biochemistry & Molecular Biology

Pancreatic Cancer: Molecular Characterization, Clonal Evolution and Cancer Stem Cells

Elvira Pelosi et al.

BIOMEDICINES (2017)

Article Oncology

Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma

Andrew J. Aguirre et al.

CANCER CELL (2017)

Article Multidisciplinary Sciences

Genomic analyses identify molecular subtypes of pancreatic cancer

Peter Bailey et al.

NATURE (2016)

Article Multidisciplinary Sciences

Whole genomes redefine the mutational landscape of pancreatic cancer

Nicola Waddell et al.

NATURE (2015)

Article Multidisciplinary Sciences

Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets

Agnieszka K. Witkiewicz et al.

NATURE COMMUNICATIONS (2015)

Article Biotechnology & Applied Microbiology

CCR7 Regulates Cell Migration and Invasion through JAK2/STAT3 in Metastatic Squamous Cell Carcinoma of the Head and Neck

Fa-Yu Liu et al.

BIOMED RESEARCH INTERNATIONAL (2014)

Article Agriculture, Multidisciplinary

Chemopreventive Effects of 4-Methylthio-3-butenyl Isothiocyanate (Raphasatin) but Not Curcumin against Pancreatic Carcinogenesis in Hamsters

Toshiya Okamura et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2013)

Article Nutrition & Dietetics

Pharmacokinetics of fucoxanthinol in human plasma after the oral administration of kombu extract

Takashi Hashimoto et al.

BRITISH JOURNAL OF NUTRITION (2012)

Article Oncology

Lack of CCR7 expression is rate limiting for lymphatic spread of pancreatic ductal adenocarcinoma

Jan Sperveslage et al.

INTERNATIONAL JOURNAL OF CANCER (2012)

Article Food Science & Technology

Single and 13-Week Oral Toxicity Study of Fucoxanthin Oil from Microalgae in Rats

Kumiko Iio et al.

FOOD HYGIENE AND SAFETY SCIENCE (2011)

Article Medicine, Research & Experimental

BTLA mediates inhibition of human tumor-specific CD8(+) T cells that can be partially reversed by vaccination

Laurent Derre et al.

JOURNAL OF CLINICAL INVESTIGATION (2010)

Article Nutrition & Dietetics

Keto-Carotenoids Are the Major Metabolites of Dietary Lutein and Fucoxanthin in Mouse Tissues

Lina Yonekura et al.

JOURNAL OF NUTRITION (2010)

Article Biochemistry & Molecular Biology

Cancer prevention by carotenoids

Hoyoku Nishino et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2009)

Article Toxicology

Single and repeated oral dose toxicity study of fucoxanthin (FX), a marine carotenoid, in mice

Fumiaki Beppu et al.

JOURNAL OF TOXICOLOGICAL SCIENCES (2009)

Review Immunology

Balancing co-stimulation and inhibition with BTLA and HVEM

Kenneth M. Murphy et al.

NATURE REVIEWS IMMUNOLOGY (2006)

Article Ophthalmology

Effects of fucoxanthin on lipopolysaccharide-induced inflammation in vitro and in vivo

K Shiratori et al.

EXPERIMENTAL EYE RESEARCH (2005)