相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Glycogen synthesis and beyond, a comprehensive review of GSK3 as a key regulator of metabolic pathways and a therapeutic target for treating metabolic diseases
Li Wang et al.
MEDICINAL RESEARCH REVIEWS (2022)
Isoginkgetin attenuates endoplasmic reticulum stress-induced autophagy of brain after ischemic reperfusion injury
Yueyong Li et al.
BIOENGINEERED (2022)
Hayatine inhibits amino acid-induced mTORC1 activation as a novel mTOR-Rag A/C interaction disruptor
Meiling Lu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2021)
Translation Inhibitors Activate Autophagy Master Regulators TFEB and TFE3
Thao Thi Dang et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
CHIR99021, trough GSK-3β Targeting, Reduces Epithelioid Sarcoma Cell Proliferation by Activating Mitotic Catastrophe and Autophagy
Sabino Russi et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
GSK3B induces autophagy by phosphorylating ULK1
Hye Young Ryu et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2021)
REGULATION AND METABOLIC FUNCTIONS OF mTORC1 AND mTORC2
Angelia Szwed et al.
PHYSIOLOGICAL REVIEWS (2021)
Effect of eukaryotic translation initiation factor 4A3 in malignant tumors
Yuanhang Zhu et al.
ONCOLOGY LETTERS (2021)
TFEB Biology and Agonists at a Glance
Mingyue Chen et al.
CELLS (2021)
A dysfunctional TRPV4-GSK3β pathway prevents osteoarthritic chondrocytes from sensing changes in extracellular matrix viscoelasticity
Pranay Agarwal et al.
NATURE BIOMEDICAL ENGINEERING (2021)
Activation of mTORC1 by Free Fatty Acids Suppresses LAMP2 and Autophagy Function via ER Stress in Alcohol-Related Liver Disease
Wei Guo et al.
CELLS (2021)
eIF4A3 regulates the TFEB-mediated transcriptional response via GSK3B to control autophagy
Despoina Sakellariou et al.
CELL DEATH AND DIFFERENTIATION (2021)
Enhanced Activity of Exportin-1/CRM1 in Neurons Contributes to Autophagy Dysfunction and Senescent Features in Old Mouse Brain
Elisa Gorostieta-Salas et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2021)
CIB2 regulates mTORC1 signaling and is essential for autophagy and visual function
Saumil Sethna et al.
NATURE COMMUNICATIONS (2021)
The Hippo kinase LATS2 impairs pancreatic β-cell survival in diabetes through the mTORC1-autophagy axis
Ting Yuan et al.
NATURE COMMUNICATIONS (2021)
Eukaryotic Initiation Factor 4A-3: A Review of Its Physiological Role and Involvement in Oncogenesis
Jiazhou Ye et al.
FRONTIERS IN ONCOLOGY (2021)
Regulation of mTORC1 by amino acids in mammalian cells: A general picture of recent advances
Shizhe Zhang et al.
ANIMAL NUTRITION (2021)
Autophagosome-Lysosome Fusion
Peter Lorincz et al.
JOURNAL OF MOLECULAR BIOLOGY (2020)
Autophagosome Biogenesis Machinery
Simon A. Walker et al.
JOURNAL OF MOLECULAR BIOLOGY (2020)
An antibody for analysis of autophagy induction
Wensheng Tian et al.
NATURE METHODS (2020)
Molecular regulation of autophagy machinery by mTOR-dependent and -independent pathways
Md Abdul Alim Al-Bari et al.
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES (2020)
Distinct Roles of mTOR Targets S6K1 and S6K2 in Breast Cancer
Savitha Sridharan et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
mTOR at the nexus of nutrition, growth, ageing and disease
Grace Y. Liu et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2020)
Glycogen synthase kinase 3 beta activity is essential for Polo-like kinase 2-and Leucine-rich repeat kinase 2-mediated regulation of alpha-synuclein
Rikke H. Kofoed et al.
NEUROBIOLOGY OF DISEASE (2020)
Inhibiting Forkhead box K1 induces autophagy to reverse epithelial-mesenchymal transition and metastasis in gastric cancer by regulating Myc-associated zinc finger protein in an acidic microenvironment
Yixuan Wang et al.
AGING-US (2020)
Investigating AKT activation and autophagy in immunoproteasome-deficient retinal cells
Md. Razaul Karim et al.
PLOS ONE (2020)
mTOR signaling pathway and mTOR inhibitors in cancer: progress and challenges
Zhilin Zou et al.
CELL AND BIOSCIENCE (2020)
Lysosomal Biology and Function: Modern View of Cellular Debris Bin
Purvi C. Trivedi et al.
CELLS (2020)
GSK3: A Kinase Balancing Promotion and Resolution of Inflammation
Leonie Hoffmeister et al.
CELLS (2020)
Autophagy as a decisive process for cell death
Seonghee Jung et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2020)
MTOR-initiated metabolic switch and degeneration in the retinal pigment epithelium
Young-Mi Go et al.
FASEB JOURNAL (2020)
GSK-3-TSC axis governs lysosomal acidification through autophagy and endocytic pathways
Limor Avrahami et al.
CELLULAR SIGNALLING (2020)
Transcription factor EB and TFE3: new metabolic coordinators mediating adaptive responses to exercise in skeletal muscle?
Greg Robert Markby et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2020)
Autophagy Upregulation by the TFEB Inducer Trehalose Protects against Oxidative Damage and Cell Death Associated with NRF2 Inhibition in Human RPE Cells
Samuel Abokyi et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2020)
Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion
Kazuaki Matoba et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2020)
A pan-cancer assessment of alterations of the kinase domain of ULK1, an upstream regulator of autophagy
Mukesh Kumar et al.
SCIENTIFIC REPORTS (2020)
Hepcidin Decreases Rotenone-Induced α-Synuclein Accumulation via Autophagy in SH-SY5Y Cells
Meiqi Li et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2020)
Regulation of mTORC1 by Upstream Stimuli
Chase H. Melick et al.
GENES (2020)
Recent Advances on the Role of GSK3β in the Pathogenesis of Amyotrophic Lateral Sclerosis
Hyun-Jun Choi et al.
BRAIN SCIENCES (2020)
Amino acid-dependent control of mTORC1 signaling: a variety of regulatory modes
Terunao Takahara et al.
JOURNAL OF BIOMEDICAL SCIENCE (2020)
Activation of TFEB-mediated autophagy by trehalose attenuates mitochondrial dysfunction in cisplatin-induced acute kidney injury
Lingling Zhu et al.
THERANOSTICS (2020)
FoxK1 and FoxK2 in insulin regulation of cellular and mitochondrial metabolism
Masaji Sakaguchi et al.
NATURE COMMUNICATIONS (2019)
Transcriptional Regulation of Autophagy: Mechanisms and Diseases
Chiara Di Malta et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2019)
Regulation of GSK3 cellular location by FRAT modulates mTORC1-dependent cell growth and sensitivity to rapamycin
Long He et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
The Emerging Roles of mTORC1 in Macromanaging Autophagy
Akpedje S. Dossou et al.
CANCERS (2019)
Biological Functions of Autophagy Genes: A Disease Perspective
Beth Levine et al.
CELL (2019)
mTORC1 as a Regulator of Mitochondrial Functions and a Therapeutic Target in Cancer
Karen Griselda de la Cruz Lopez et al.
FRONTIERS IN ONCOLOGY (2019)
Abnormal mTORC1 signaling leads to retinal pigment epithelium degeneration
Jiancheng Huang et al.
THERANOSTICS (2019)
TRPM4 regulates Akt/GSK3-β activity and enhances β-catenin signaling and cell proliferation in prostate cancer cells
Alfredo I. Sagredo et al.
MOLECULAR ONCOLOGY (2018)
A negative feedback regulation of MTORC1 activity by the lysosomal Ca2+ channel MCOLN1 (mucolipin 1) using a CALM (calmodulin)-dependent mechanism
Xue Sun et al.
AUTOPHAGY (2018)
mTORC1 Signaling: A Double-Edged Sword in Diabetic β Cells
Amin Ardestani et al.
CELL METABOLISM (2018)
The complex relationship between TFEB transcription factor phosphorylation and subcellular localization
Rosa Puertollano et al.
EMBO JOURNAL (2018)
Correlation of CRM1-NES affinity with nuclear export activity
Szu-Chin Fu et al.
MOLECULAR BIOLOGY OF THE CELL (2018)
mTORC1 Promotes Metabolic Reprogramming by the Suppression of GSK3-Dependent Foxk1 Phosphorylation
Long He et al.
MOLECULAR CELL (2018)
A TFEB nuclear export signal integrates amino acid supply and glucose availability
Linxin Li et al.
NATURE COMMUNICATIONS (2018)
Nuclear Export Inhibition Enhances HLH-30/TFEB Activity, Autophagy, and Lifespan
Melissa J. Silvestrini et al.
CELL REPORTS (2018)
The Role of Insulin/IGF-1/PI3K/Akt/GSK3β Signaling in Parkinson's Disease Dementia
Liying Yang et al.
FRONTIERS IN NEUROSCIENCE (2018)
mTOR complex 1 controls the nuclear localization and function of glycogen synthase kinase 3β
Stephen J. Bautista et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
mTOR-dependent phosphorylation controls TFEB nuclear export
Gennaro Napolitano et al.
NATURE COMMUNICATIONS (2018)
Phosphorylation of ULK1 affects autophagosome fusion and links chaperone-mediated autophagy to macroautophagy
Chenyao Wang et al.
NATURE COMMUNICATIONS (2018)
A Potent and Selective ULK1 Inhibitor Suppresses Autophagy and Sensitizes Cancer Cells to Nutrient Stress
Katie R. Martin et al.
ISCIENCE (2018)
Beclin 1 Phosphorylation - at the Center of Autophagy Regulation
Manoj B. Menon et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2018)
Autophagy pathway: Cellular and molecular mechanisms
Li Yu et al.
AUTOPHAGY (2018)
The mammalian ULK1 complex and autophagy initiation
Maria Zachari et al.
SIGNALLING MECHANISMS IN AUTOPHAGY (2017)
mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases
Michela Palmieri et al.
NATURE COMMUNICATIONS (2017)
In vivo regulation of glycogen synthase kinase 3β activity in neurons and brains
Ambika Krishnankutty et al.
SCIENTIFIC REPORTS (2017)
mTORC1 Regulates Mitochondrial Integrated Stress Response and Mitochondrial Myopathy Progression
Nahid A. Khan et al.
CELL METABOLISM (2017)
AKT/PKB Signaling: Navigating the Network
Brendan D. Manning et al.
CELL (2017)
Multiple amino acid sensing inputs to mTORC1
Mitsugu Shimobayashi et al.
CELL RESEARCH (2016)
Knockdown of GSK3β increases basal autophagy and AMPK signalling in nutrient-laden human aortic endothelial cells
Karen A. Weikel et al.
BIOSCIENCE REPORTS (2016)
4E-BP1, a multifactor regulated multifunctional protein
Xiaoyu Qin et al.
CELL CYCLE (2016)
Protein kinase C controls lysosome biogenesis independently of mTORC1
Yang Li et al.
NATURE CELL BIOLOGY (2016)
Regulation of ER stress-induced autophagy by GSK3β-TIP60-ULK1 pathway
Tiejian Nie et al.
CELL DEATH & DISEASE (2016)
Dynamics of mTORC1 activation in response to amino acids
Maria Manifava et al.
ELIFE (2016)
Intracellular calcium signaling regulates autophagy via calcineurin-mediated TFEB dephosphorylation
Yanju Tong et al.
AUTOPHAGY (2015)
The mucolipidosis IV Ca2+ channel TRPML1 (MCOLN1) is regulated by the TOR kinase
Rob U. Onyenwoke et al.
BIOCHEMICAL JOURNAL (2015)
GSK3-mediated raptor phosphorylation supports amino-acid-dependent mTORC1-directed signalling
Clare Stretton et al.
BIOCHEMICAL JOURNAL (2015)
Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB
Diego L. Medina et al.
NATURE CELL BIOLOGY (2015)
Glycogen synthase kinase-3 (GSK3): Regulation, actions, and diseases
Eleonore Beurel et al.
PHARMACOLOGY & THERAPEUTICS (2015)
The molecular mechanism of rotenone-induced α-synuclein aggregation: Emphasizing the role of the calcium/GSK3β pathway
Yu-he Yuan et al.
TOXICOLOGY LETTERS (2015)
Baclofen mediates neuroprotection on hippocampal CA1 pyramidal cells through the regulation of autophagy under chronic cerebral hypoperfusion
Li Liu et al.
SCIENTIFIC REPORTS (2015)
Computational Analysis of an Autophagy/Translation Switch Based on Mutual Inhibition of MTORC1 and ULK1
Paulina Szymanska et al.
PLOS ONE (2015)
Foxk proteins repress the initiation of starvation-induced atrophy and autophagy programs
Christopher John Bowman et al.
NATURE CELL BIOLOGY (2014)
Regulation of mTORC1 by amino acids
Liron Bar-Peled et al.
TRENDS IN CELL BIOLOGY (2014)
Targeting Src-mediated Tyr216 phosphorylation and activation of GSK-3 in prostate cancer cells inhibit prostate cancer progression in vitro and in vivo
Anna Goc et al.
ONCOTARGET (2014)
Phosphorylation and degradation of S6K1 (p70S6K1) in response to persistent JNK1 Activation
Jin Zhang et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2013)
The Hairpin-type Tail-Anchored SNARE Syntaxin 17 Targets to Autophagosomes for Fusion with Endosomes/Lysosomes
Eisuke Itakura et al.
CELL (2012)
GSK3-TIP60-ULK1 Signaling Pathway Links Growth Factor Deprivation to Autophagy
Shu-Yong Lin et al.
SCIENCE (2012)
Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways
Michela Palmieri et al.
HUMAN MOLECULAR GENETICS (2011)
Convergence of the Mammalian Target of Rapamycin Complex 1-and Glycogen Synthase Kinase 3-β-Signaling Pathways Regulates the Innate Inflammatory Response
Huizhi Wang et al.
JOURNAL OF IMMUNOLOGY (2011)
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
Joungmok Kim et al.
NATURE CELL BIOLOGY (2011)
The origin of the autophagosomal membrane
Sharon A. Tooze et al.
NATURE CELL BIOLOGY (2010)
GSK3 signalling in neural development
Eun-Mi Hur et al.
NATURE REVIEWS NEUROSCIENCE (2010)
Role of CK1 in GSK3β-mediated phosphorylation and degradation of Snail
Y. Xu et al.
ONCOGENE (2010)
Regulation of protein stability by GSK3 mediated phosphorylation
Chong Xu et al.
CELL CYCLE (2009)
PIKKing on PKB: regulation of PKB activity by phosphorylation
Lana Bozulic et al.
CURRENT OPINION IN CELL BIOLOGY (2009)
A GSK-3/TSC2/mTOR pathway regulates glucose uptake and GLUT1 glucose transporter expression
Carolyn L. Buller et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2008)
Lithium delays progression of amyotrophic lateral sclerosis
Francesco Fornai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
N-terminal cleavage of GSK-3 by calpain -: A new form of GSK-3 regulation
Paloma Goni-Oliver et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Glycogen synthase kinase-3 (GSK3): Inflammation, diseases, and therapeutics
Richard S. Jope et al.
NEUROCHEMICAL RESEARCH (2007)
S6K1 regulates GSK3 under conditions of mTOR-dependent feedback inhibition of Akt
Hui H. Zhang et al.
MOLECULAR CELL (2006)
TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth
Ken Inoki et al.
CELL (2006)
Calmodulin-mediated activation of Akt regulates survival of c-Myc-overexpressing mouse mammary carcinoma cells
TB Deb et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Advances in protein kinase B signalling:: AKTion on multiple fronts
DP Brazil et al.
TRENDS IN BIOCHEMICAL SCIENCES (2004)
Phosphorylation by glycogen synthase kinase-3 controls c-Myc proteolysis and subnuclear localization
MA Gregory et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling
K Inoki et al.
GENES & DEVELOPMENT (2003)