相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。An intercrypt subpopulation of goblet cells is essential for colonic mucus barrier function
Elisabeth E. L. Nystrom et al.
SCIENCE (2021)
The epidemiology of inflammatory bowel disease: East meets west
Wing Yan Mak et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2020)
Enteric Nervous System-Derived IL-18 Orchestrates Mucosal Barrier Immunity (vol 180, pg 50, 2020)
Abigail Jarret et al.
CELL (2020)
High-fat Diet Alters the Glycosylation Patterns of Duodenal Mucins in a Murine Model
Maria Mastrodonato et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2020)
Mucins and the Microbiome
Gunnar C. Hansson
Annual Review of Biochemistry (2020)
Mucus barrier, mucins and gut microbiota: the expected slimy partners?
Paola Paone et al.
GUT (2020)
Proximal colon-derived O-glycosylated mucus encapsulates and modulates the microbiota
Kirk Bergstrom et al.
SCIENCE (2020)
Helicobacter suis infection alters glycosylation and decreases the pathogen growth inhibiting effect and binding avidity of gastric mucins
Medea Padra et al.
MUCOSAL IMMUNOLOGY (2019)
Colonic epithelial cell diversity in health and inflammatory bowel disease
Kaushal Parikh et al.
NATURE (2019)
Aryl hydrocarbon receptor activation alleviates dextran sodium sulfate-induced colitis through enhancing the differentiation of goblet cells
Jiuheng Yin et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2019)
Bifidobacterium dentium Fortifies the Intestinal Mucus Layer via Autophagy and Calcium Signaling Pathways
Melinda A. Engevik et al.
MBIO (2019)
The potential probiotic Lactobacillus rhamnosus CNCM 1-3690 strain protects the intestinal barrier by stimulating both mucus production and cytoprotective response
Rebeca Martin et al.
SCIENTIFIC REPORTS (2019)
The Nlrp6 inflammasome is not required for baseline colonic inner mucus layer formation or function
Joana K. Volk et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2019)
Intestinal epithelial cells: at the interface of the microbiota and mucosal immunity
Amelia T. Soderholm et al.
IMMUNOLOGY (2019)
Interactions Between Autophagy and the Unfolded Protein Response: Implications for Inflammatory Bowel Disease
Kirsty M. Hooper et al.
INFLAMMATORY BOWEL DISEASES (2019)
Experimental models to study intestinal microbes-mucus interactions in health and disease
Lucie Etienne-Mesmin et al.
FEMS MICROBIOLOGY REVIEWS (2019)
The Food Additive Maltodextrion promotes Endoplasmic Reticulum Stress-Driven Mucus Depletion and Exacerbates Intestinal Inflammation
Federica Laudisi et al.
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY (2019)
The biology of mucus: Composition, synthesis and organization
Rama Bansil et al.
ADVANCED DRUG DELIVERY REVIEWS (2018)
Bifidobacteria or Fiber Protects against Diet-Induced Microbiota-Mediated Colonic Mucus Deterioration
Bjoern O. Schroeder et al.
CELL HOST & MICROBE (2018)
Segmented Filamentous Bacteria - Metabolism Meets Immunity
Grant A. Hedblom et al.
FRONTIERS IN MICROBIOLOGY (2018)
Resistin-like molecule β is a bactericidal protein that promotes spatial segregation of the microbiota and the colonic epithelium
Daniel C. Propheter et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Role of autophagy in the pathogenesis of inflammatory bowel disease
Tomoya Iida et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2017)
Quantity and source of dietary protein influence metabolite production by gut microbiota and rectal mucosa gene expression: a randomized, parallel, double-blind trial in overweight humans
Martin Beaumont et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2017)
Temporal microbiota changes of high-protein diet intake in a rat model
Chunlong Mu et al.
ANAEROBE (2017)
Indoleacrylic Acid Produced by Commensal Peptostreptococcus Species Suppresses Inflammation
Marta Wlodarska et al.
CELL HOST & MICROBE (2017)
Mice deficient in Muc4 are resistant to experimental colitis and colitis-associated colorectal cancer
S. Das et al.
ONCOGENE (2016)
A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility
Mahesh S. Desai et al.
CELL (2016)
Mucin gene expression in the intestine of ulcerative colitis patients: a systematic review and meta-analysis
Yaron Niv
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY (2016)
The Colonic Microbiome and Epithelial Transcriptome Are Altered in Rats Fed a High-Protein Diet Compared with a Normal-Protein Diet
Chunlong Mu et al.
JOURNAL OF NUTRITION (2016)
High Fat Diets Induce Colonic Epithelial Cell Stress and Inflammation that is Reversed by IL-22
Max Gulhane et al.
SCIENTIFIC REPORTS (2016)
Revised Estimates for the Number of Human and Bacteria Cells in the Body
Ron Sender et al.
PLOS BIOLOGY (2016)
Human Intestinal Barrier Function in Health and Disease
Julia Konig et al.
CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY (2016)
Western diet induces a shift in microbiota composition enhancing susceptibility to Adherent-Invasive E. coli infection and intestinal inflammation
Allison Agus et al.
SCIENTIFIC REPORTS (2016)
Immunological aspects of intestinal mucus and mucins
Malin E. V. Johansson et al.
NATURE REVIEWS IMMUNOLOGY (2016)
Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling
Maayan Levy et al.
CELL (2015)
Epithelial IL-18 Equilibrium Controls Barrier Function in Colitis
Roni Nowarski et al.
CELL (2015)
Quantitative Imaging of Gut Microbiota Spatial Organization
Kristen A. Earle et al.
CELL HOST & MICROBE (2015)
Normalization of Host Intestinal Mucus Layers Requires Long-Term Microbial Colonization
Malin E. V. Johansson et al.
CELL HOST & MICROBE (2015)
High-protein diet differently modifies intestinal goblet cell characteristics and mucosal cytokine expression in ileum and colon
Annaig Lan et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2015)
Differential Expression of MUC12, MUC16, and MUC20 in Patients with Active and Remission Ulcerative Colitis
Jesus K. Yamamoto-Furusho et al.
MEDIATORS OF INFLAMMATION (2015)
New developments in goblet cell mucus secretion and function
G. M. H. Birchenough et al.
MUCOSAL IMMUNOLOGY (2015)
Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome
Benoit Chassaing et al.
NATURE (2015)
The outer mucus layer hosts a distinct intestinal microbial niche
Hai Li et al.
NATURE COMMUNICATIONS (2015)
Correction: SslE Elicits Functional Antibodies That Impair In Vitro Mucinase Activity and In Vivo Colonization by Both Intestinal and Extraintestinal Escherichia coli Strains
PLoS Pathogens (2015)
Mucin glycan foraging in the human gut microbiome
Louise E. Tailford et al.
FRONTIERS IN GENETICS (2015)
The composition of the gut microbiota shapes the colon mucus barrier
Hedvig E. Jakobsson et al.
EMBO REPORTS (2015)
Roles and regulation of the mucus barrier in the gut
Steve Cornick et al.
TISSUE BARRIERS (2015)
NLRP6 Inflammasome Orchestrates the Colonic Host-Microbial Interface by Regulating Goblet Cell Mucus Secretion
Marta Wlodarska et al.
CELL (2014)
Western diet induces dysbiosis with increased E coli in CEABAC10 mice, alters host barrier function favouring AIEC colonisation
Margarita Martinez-Medina et al.
GUT (2014)
Bacterial Sensor Nod2 Prevents Inflammation of the Small Intestine by Restricting the Expansion of the Commensal Bacteroides vulgatus
Deepshika Ramanan et al.
IMMUNITY (2014)
The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system
Thaher Pelaseyed et al.
IMMUNOLOGICAL REVIEWS (2014)
Enterotoxigenic Escherichia coli Secretes a Highly Conserved Mucin-Degrading Metalloprotease To Effectively Engage Intestinal Epithelial Cells
Qingwei Luo et al.
INFECTION AND IMMUNITY (2014)
Adult intestinal stem cells: critical drivers of epithelial homeostasis and regeneration
Nick Barker
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
The Vibrio cholerae Extracellular Chitinase ChiA2 Is Important for Survival and Pathogenesis in the Host Intestine
Moumita Mondal et al.
PLOS ONE (2014)
Microbial-induced meprin β cleavage in MUC2 mucin and a functional CFTR channel are required to release anchored small intestinal mucus
Andre Schutte et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Studies of mucus in mouse stomach, small intestine, and colon. I. Gastrointestinal mucus layers have different properties depending on location as well as over the Peyer's patches
Anna Ermund et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2013)
Paneth Cells: Maestros of the Small Intestinal Crypts
Hans C. Clevers et al.
ANNUAL REVIEW OF PHYSIOLOGY, VOL 75 (2013)
The Intestinal Crypt, A Prototype Stem Cell Compartment
Hans Clevers
CELL (2013)
Autophagy proteins control goblet cell function by potentiating reactive oxygen species production
Khushbu K. Patel et al.
EMBO JOURNAL (2013)
IL-10 Promotes Production of Intestinal Mucus by Suppressing Protein Misfolding and Endoplasmic Reticulum Stress in Goblet Cells
Sumaira Z. Hasnain et al.
GASTROENTEROLOGY (2013)
Inhibition of Water Absorption and Selective Damage to Human Colonic Mucosa Are Induced by Subtilase Cytotoxin Produced by Escherichia coli O113:H21
Elizabeth Gerhardt et al.
INFECTION AND IMMUNITY (2013)
A new role for mucins in immunity: Insights from gastrointestinal nematode infection
Sumaira Z. Hasnain et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2013)
Mucin Function in Inflammatory Bowel Disease An Update
Doron Boltin et al.
JOURNAL OF CLINICAL GASTROENTEROLOGY (2013)
Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study
Karen L. Kotloff et al.
LANCET (2013)
The gastrointestinal mucus system in health and disease
Malin E. V. Johansson et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2013)
The gut microbiota - masters of host development and physiology
Felix Sommer et al.
NATURE REVIEWS MICROBIOLOGY (2013)
Mucus Enhances Gut Homeostasis and Oral Tolerance by Delivering Immunoregulatory Signals
Meimei Shan et al.
SCIENCE (2013)
Fatty Acid Synthase Modulates Intestinal Barrier Function through Palmitoylation of Mucin 2
Xiaochao Wei et al.
CELL HOST & MICROBE (2012)
Reduced expression of mucin 9 (MUC9) in patients with ulcerative colitis
Jesus K. Yamamoto-Furusho et al.
INFLAMMATORY BOWEL DISEASES (2012)
Mucins in inflammatory bowel diseases and colorectal cancer
Yong H. Sheng et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2012)
Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine
Jeremiah R. McDole et al.
NATURE (2012)
Altered O-glycosylation Profile of MUC2 Mucin Occurs in Active Ulcerative Colitis and Is Associated with Increased Inflammation
Jessica M. Holmen Larsson et al.
INFLAMMATORY BOWEL DISEASES (2011)
TagA is a secreted protease of Vibrio cholerae that specifically cleaves mucin glycoproteins
Rose L. Szabady et al.
MICROBIOLOGY-SGM (2011)
The two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host-microbial interactions
Malin E. V. Johansson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
The combination of fructooligosaccharides and resistant starch shows prebiotic additive effects in rats
Maria Elena Rodriguez-Cabezas et al.
CLINICAL NUTRITION (2010)
Pic, an Autotransporter Protein Secreted by Different Pathogens in the Enterobacteriaceae Family, Is a Potent Mucus Secretagogue
Fernando Navarro-Garcia et al.
INFECTION AND IMMUNITY (2010)
Muc2 Protects against Lethal Infectious Colitis by Disassociating Pathogenic and Commensal Bacteria from the Colonic Mucosa
Kirk S. B. Bergstrom et al.
PLOS PATHOGENS (2010)
Barrier properties of mucus
Richard A. Cone
ADVANCED DRUG DELIVERY REVIEWS (2009)
The regulation of intestinal mucin MUC2 expression by short-chain fatty acids: implications for epithelial protection
Nanda Burger-van Paassen et al.
BIOCHEMICAL JOURNAL (2009)
The thickness of the intestinal mucous layer in the colon of rats fed various sources of non-digestible carbohydrates is positively correlated with the pool of SCFA but negatively correlated with the proportion of butyric acid in digesta
Mette S. Hedemann et al.
BRITISH JOURNAL OF NUTRITION (2009)
The Ets-Domain Transcription Factor Spdef Promotes Maturation of Goblet and Paneth Cells in the Intestinal Epithelium
Alex Gregorieff et al.
GASTROENTEROLOGY (2009)
Reduced mucin sulfonation and impaired intestinal barrier function in the hyposulfataemic NaS1 null mouse
P. A. Dawson et al.
GUT (2009)
Role of Intestinal Mucins in Innate Host Defense Mechanisms against Pathogens
Poonam Dharmani et al.
JOURNAL OF INNATE IMMUNITY (2009)
The protein disulfide isomerase AGR2 is essential for production of intestinal mucus
Sung-Woo Park et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Butyrate Enemas Upregulate Muc Genes Expression but Decrease Adherent Mucus Thickness in Mice Colon
E. Gaudier et al.
PHYSIOLOGICAL RESEARCH (2009)
Regulation of airway mucin gene expression
Philip Thai et al.
ANNUAL REVIEW OF PHYSIOLOGY (2008)
Thickness and continuity of the adherent colonic mucus barrier in active and quiescent ulcerative colitis and Crohn's disease
V. Strugala et al.
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE (2008)
IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis
Ken Sugimoto et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
Jeffrey C. Barrett et al.
NATURE GENETICS (2008)
Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis
Chad K. Heazlewood et al.
PLOS MEDICINE (2008)
Gel-forming mucins appeared early in metazoan evolution
Tiange Lang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Unravelling the pathogenesis of inflammatory bowel disease
R. J. Xavier et al.
NATURE (2007)
Increased susceptibility to colitis and colorectal tumors in mice lacking core 3-derived O-glycans
Guangyu An et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
The VSL#3 probiotic formula induces mucin gene expression and secretion in colonic epithelial cells
C. Caballero-Franco et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2007)
Aberrant intestinal expression and allelic variants of mucin genes associated with inflammatory bowel disease
Christoph Moehle et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2006)
Entamoeba histallytica cysteine proteases cleave the MUC2 mucin in its C-terminal domain and dissolve the protective colonic mucus gel
Martin E. Lidell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Effects of topical treatment of sodium butyrate and 5-aminosalicylic acid on expression of trefoil factor 3, interleukin 1β, and nuclear factor κB in trinitrobenzene sulphonic acid induced colitis in rats
M Song et al.
POSTGRADUATE MEDICAL JOURNAL (2006)
Enterotoxigenic Escherichia coli in developing countries:: Epidemiology, microbiology, clinical features, treatment, and prevention
F Qadri et al.
CLINICAL MICROBIOLOGY REVIEWS (2005)
Glycan foraging in vivo by an intestine-adapted bacterial symbiont
JL Sonnenburg et al.
SCIENCE (2005)
IL-4 and IL-13 up-regulate intestinal trefoil factor expression: Requirement for STAT6 and de novo protein synthesis
C Blanchard et al.
JOURNAL OF IMMUNOLOGY (2004)
Short chain fatty acids stimulate epithelial mucin 2 expression through differential effects on prostaglandin E1 and E2 production by intestinal myofibroblasts
LEM Willemsen et al.
GUT (2003)
mRNA of MUC2 is stimulated by IL-4, IL-13 or TNF-α through a mitogen-activated protein kinase pathway in human colon cancer cells
J Iwashita et al.
IMMUNOLOGY AND CELL BIOLOGY (2003)
Colonic mucus: secretion and turnover in relation to dietary fibre intake
IA Brownlee et al.
PROCEEDINGS OF THE NUTRITION SOCIETY (2003)
Regulation of JAK-STAT signalling in the immune system
K Shuai et al.
NATURE REVIEWS IMMUNOLOGY (2003)
LPS up-regulates mucin and cytokine mRNA expression and stimulates mucin and cytokine secretion in goblet cells
MG Smirnova et al.
CELLULAR IMMUNOLOGY (2003)
Probiotics up-regulate MUC-2 mucin gene expression in a Caco-2 cell-culture model
AF Mattar et al.
PEDIATRIC SURGERY INTERNATIONAL (2002)
Disruption in gastric mucin synthesis by Helicobacter pylori lipopolysaccharide involves ERK and p38 mitogen-activated protein kinase participation
BL Slomiany et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
IL-13 suppresses MUC5AC gene expression and mucin secretion in nasal epithelial cells
CH Kim et al.
ACTA OTO-LARYNGOLOGICA (2002)
Platelet-activating factor receptor and ADAM10 mediate responses to Staphylococcus aureus in epithelial cells
H Lemjabbar et al.
NATURE MEDICINE (2002)
Signaling networks controlling mucin production in response to Gram-positive and Gram-negative bacteria
N McNamara et al.
GLYCOCONJUGATE JOURNAL (2001)
Interleukin-9 upregulates mucus expression in the airways
J Louahed et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2000)
Inhibition of gastric mucin synthesis by Helicobacter pylori
JC Byrd et al.
GASTROENTEROLOGY (2000)
Proinflammatory cytokines trigger MUC gene expression and mucin release in the intestinal cancer cell line LS180
ML Enss et al.
INFLAMMATION RESEARCH (2000)