期刊
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
卷 111, 期 -, 页码 130-137出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.ijid.2021.08.033
关键词
Lower respiratory tract infection; LRTI; American Indian; Alaska Native (AI; AN); Alaska; Vaccine; Invasive pneumococcal disease
资金
- Arctic Investigations Program, CDC
- Indian Health Service
The study revealed a 26% increase in LRTI rates among adult AI/AN residing in AK compared to a 38% decrease in rates among AI/AN residing in non-AK, likely due to factors such as tobacco use and crowding. Strategies to reduce LRTI in AI/AN adults are necessary.
Objectives: This study describes the changes in lower respiratory tract infection (LRTI) rates from 1998 to 2014 among hospitalized American Indian/Alaska Native (AI/AN) adults residing in Alaska and other Indian Health Service (IHS) regions. Methods: Age-adjusted hospital discharge rates and rate ratios were calculated from the IHS Direct and Contract Health Services Inpatient Dataset, IHS National Patient Information Reporting System for AI/AN adults >18 years, hospitalized at an IHS-operated, tribally operated, or contract hospital with an LRTI-associated diagnosis during 1998-2014. Results: Overall, there were 13 733 LRTI-associated hospitalizations in Alaska (1998-2014), with an age-adjusted rate of 13.7/10 0 0 adults. Among non-Alaska (non-AK) AI/AN, there were a total of 79 170 hospitalizations, with a rate of 8.6/10 0 0 adults. In the pre-PCV7 and pre-PCV13 periods, LRTI rates were higher in Alaska (AK) AI/AN (12.4 and 14.1, respectively) when compared to non-AK AI/AN (10.1 and 9.1, respectively) ( P < 0.0 0 01). In the post-PCV7 and post-PCV13 periods, LRTI rates were also higher in AK (13.5 and 15.0, respectively) compared to non-AK (9.2 and 7.3, respectively) ( P < 0.0 0 01). Conclusions: Over the study period, a 26% increase in rates of LRTI among adult AI/AN residing in AK compared with a 38% decrease in rates among AI/AN residing in non-AK were observed. This disparity is likely due to a variety of factors such as tobacco use, crowding, etc. Strategies to reduce LRTI in AI/AN adults are needed. (c) 2021 Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
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