期刊
INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
卷 66, 期 1-3, 页码 163-175出版社
UNIV BASQUE COUNTRY UPV-EHU PRESS
DOI: 10.1387/ijdb.210189kk
关键词
non-coding RNAs; microRNAs; RNA interference; abiotic stress; biotic stress
资金
- European Union (European Social Fund-ESF) through the Operational Program Human Resources Development, Education and Lifelong Learning [MIS-5033021]
- project Development of national research network to Grape, Division 1. (Development of national research network to Olive, to Grape, to Honey, and to Livestock) of the National Scale of the Public Investments Program of the General Secretariat [2018S.01300000]
- Operational Program Crete 2014-20'' [OPS (MIS) 5022230]
- European Union (European Structural and Investment Funds)
RNA silencing is a crucial conserved eukaryotic process in plants, with different classes of non-coding RNAs such as miRNAs playing key roles in regulating gene expression. miRNAs are core components of the endogenous gene silencing pathway, modulating gene expression and participating in various biological processes.
RNA silencing refers to a conserved eukaryotic process and is regarded as one of the most important processes in plants, with the ability to regulate gene expression both transcriptionally and post-transcriptionally. Different classes of non-coding RNAs (ncRNAs) constitute key components of the RNA silencing pathways and play pivotal roles in modulating various biological processes as well as host-pathogen interactions. One of the most extensively studied classes of ncRNAs are the 20-24 nucleotide (nt) long microRNAs (miRNAs), which are core components of the endogenous gene silencing pathway. miRNAs act as negative regulators of endogenous gene expression through either mRNA-target cleavage, translational inhibition, or DNA methylation, and are inextricably linked to a plethora of developmental processes, such as leaf pattern formation as well as abiotic and biotic stress responses. In this review, we focus on the role of the RNA silencing pathways in the regulation of developmental processes as well as in the plant responses to biotic stress.
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