4.7 Article

Vaccine design and delivery approaches for COVID-19

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INTERNATIONAL IMMUNOPHARMACOLOGY
卷 100, 期 -, 页码 -

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ELSEVIER
DOI: 10.1016/j.intimp.2021.108086

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COVID-19; SARS-CoV-2; Vaccine; Vaccine design; Vaccine delivery

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During the COVID-19 pandemic, the development and application of vaccines have become crucial in combating the spread of the virus, with effective vaccines playing a significant role in reducing the burden and transmission of the disease. While some vaccines have been released ahead of schedule, potential side effects must also be carefully considered.
COVID-19 is still a deadly disease that remains yet a major challenge for humans. In recent times, many large pharmaceutical and non-pharmaceutical companies have invested a lot of time and cost in fighting this disease. In this regard, today's scientific knowledge shows that designing and producing an effective vaccine is the best possible way to diminish the disease burden and dissemination or even eradicate the disease. Due to the urgent need, many vaccines are now available earlier than scheduled. New technologies have also helped to produce much more effective vaccines, although the potential side effects must be taken into account. Thus, in this review, the types of vaccines and vaccine designs made against COVID-19, the vaccination programs, as well as the delivery methods and molecules that have been used to deliver some vaccines that need a carrier will be described.

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