4.5 Review

A critical analysis of research methods and experimental models to study irrigants and irrigation systems

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Summary: The study found that ultrasonic activation and high flow rate significantly increased the removal of biofilm from the artificial lateral canal, while no significant differences were found between the groups for biofilm removal from the artificial isthmus. RISA and NaOCl exhibited the greatest anti-biofilm efficacy in decontaminating infected dentinal tubules.

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Biofilm removal from a simulated isthmus and lateral canal during syringe irrigation at various flow rates: a combined experimental and Computational Fluid Dynamics approach

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Summary: The study found that flow rate significantly influenced biofilm removal in the simulated isthmus and lateral canal, with higher flow rates leading to increased biofilm removal. In this experiment, the concentration of NaOCl did not have a significant effect on biofilm removal. The velocity of the irrigant was found to be correlated with biofilm removal in the isthmus and lateral canal.

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Doxycycline-functionalized polymeric nanoparticles inhibit Enterococcus faecalis biofilm formation on dentine

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Model system parameters influence the sodium hypochlorite susceptibility of endodontic biofilms

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