4.2 Article

Significance of Cortical Ribboning as a Biomarker in the Prodromal Phase of Sporadic Creutzfeldt-Jakob Disease

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Summary: Sporadic Creutzfeldt-Jakob disease is a fatal neurodegenerative disease caused by misfolded prion proteins. Its diagnosis relies on a combination of neuropsychiatric symptoms, CSF markers, and imaging. The development of assays like RT-QuIC has improved diagnostic accuracy.

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