期刊
INTERNAL MEDICINE
卷 61, 期 21, 页码 3265-3269出版社
JAPAN SOC INTERNAL MEDICINE
DOI: 10.2169/internalmedicine.8859-21
关键词
acute myeloid leukemia; bone marrow necrosis; Charcot-Leyden crystals
This report presents a suspected case of AML that was diagnostically challenging due to complete BMN with CLCs. However, the patient achieved complete hematologic remission with treatment similar to that for AML.
Bone marrow necrosis (BMN) has various underlying diseases. In hematological malignancies, both lym-phoid and myeloid neoplasms have been shown to cause BMN. Charcot-Leyden crystals (CLCs) are bipyramidal crystals that have been found in patients with immune system diseases, tumors, skin diseases, asthma, infections, and intestinal diseases. Because the combination of CLCs and acute myeloid leukemia (AML) is rare, the relationship between BMN, CLCs, and AML remains largely unexplored. We herein report a suspected case of AML that was difficult to diagnose morphologically because of complete BMN with CLCs but achieved complete hematologic remission with treatment similar to that for AML.
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