Dual-role of β borophene nanosheets as highly effective antibacterial and antifungal agent

Antimicrobial resistance toward antibiotics has been a serious clinical problem to current bacterial infections therapy. In this context, current research and development have been focused on developing new perspectives on two-dimensional (2D) materials based antimicrobial agents. With the rapid development of 2D borophene, it has been regarded as a promising agent for sensor, energy, and biomedical applications. Herein, we have reported the fabrication of the multifunctional antibacterial and antifungal agent, beta-rhombohedral crystalline structured borophene nanosheets, which were prepared using a top-down synthesis approach. The antibacterial and antifungal activities of beta borophene nanosheets were investigated to determine using different pathogenic microorganisms such as Staphylococcus aureus (NCTC 10788/Lot 0350520029), Pseudomonas aureginosa (ATCC 9027/Lot 3270513), Escherichia coli (ATCC 8739/Lot 4835151), Candida albicans (NCPF 3179/Lot040920020), and Aspergillus brasilliensis (NCPF 2275/Lot 020620065) using the total aerobic mesophilic microorganism (lSO 21149) and mold-yeast (lSO 16212) guidelines. According to the experimental results, we showed that the borophene nanosheets had an effectively inhibitory activity against several medically serious bacterial and fungal pathogenic microorganisms.

Automated summary

Antibiotic resistance has been a major concern in bacterial infection therapy, prompting the development of new antimicrobial agents. This study focuses on the fabrication of multifunctional antibacterial and antifungal agents using borophene nanosheets, which showed inhibitory activity against various pathogenic microorganisms.