Novel aspartic chiral optical sensor based on 13-cyclodextrin-functionalized CdTe nanoparticles

Based on the quenching effect of fluorescence intensity of CdTe nanoparticles coated 13-cyclodextrin, a novel aspartic chiral assay is suggested. The CdTe nanoparticles were synthesized by co-precipitate and then modified with 13-cyclodextrin through a sonication technique to get CdTe@13CD nanoparticles. To characterize CdTe@13CD, FT-IR spectra, fluorescence spectroscopy, and transmission electron microscope were applied. The coupling of host-guest interaction of 13-cyclodextrin and aspartic and the fluorescence quenching effect resulted in high selectivity on aspartic of CdTe@13CD sensor. The quenching process was described by the Stern-Volmer equation. The available mechanism of the assay is proposed. Under optimal conditions, the limit of detection of the assay for D-aspartic form was calculated to be 19 ng/mL. The proposed aspartic chiral assay exhibited as a simple and rapid sensing method.

Automated summary

A novel aspartic chiral assay based on CdTe nanoparticles coated with 13-cyclodextrin was proposed, showing high selectivity and good detection performance.