4.7 Article

Genetic engineering of tropane alkaloid biosynthesis of hyoscyamus reticulatus L. hairy roots by pmt gene overexpression and feeding with putrescine

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Summary: Hairy roots, or transformed root cultures, provide a feasible approach for producing valuable secondary metabolites from medicinal plants. Various strategies have been used to enhance secondary metabolite production in hairy roots, including increasing substrate availability, regulating key biosynthetic genes, multigene engineering, and introducing new genes. Recent research focuses on techniques to boost production of desired secondary metabolites and the development of new technologies to study these metabolites.

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