Investigating the Photothermal Disinfecting Properties of Light-Activated Silver Nanoparticles

The medicinal applications of noble metal nanomaterials are of considerable interest due to the unique properties they possess. The following contribution will showcase one of these properties, the photothermal effect produced by silver nanoparticles (AgNPs), and show how AgNPs can serve as potential viricidal materials for PPE (i.e., personal protective equipment) disinfection. In the context of the COVID-19 global pandemic, PPE disinfection is critical for addressing the shortfalls in the supply chains that ensure rapid and reliable sources of PPE for both medical professionals and the public. Two AgNP composites were prepared using both photochemical and pulsed laser ablation in liquid techniques. Then, to improve the durability of the NPs' coating, they were mixed in a commercially available tent protectant solution or with a chitosan suspension. Transmission electron microscopy and spectroscopic analyses of the AgNP/protectant composites present mostly monodisperse, spherical particles of similar to 5-10 nm in diameter, dependent on the route of nanoparticle synthesis. Blue light-emitting diodes (LEDs) were utilized to activate the surface plasmon resonance effects of the AgNP-coated materials at similar to 400 nm. The resultant photothermal activation produced elevated surface temperatures on the fabrics, up to 150 degrees C, approaching the ignition temperature of the fabric samples, and well above the threshold required to deactivate the SARS-CoV-2 virus responsible for the COVID-19 pandemic. Photothermal heating was found to be largely dependent on both proximity of the coated sample surface to the LED source and illumination intensity. Furthermore, the rate of temperature increase was determined to be considerably faster than traditional or photothermal heating studies conducted on aqueous nanoparticle colloids, illustrating the efficiency of this methodology. Finally, durability studies of the AgNP/protectant coatings were examined and were found to maintain photothermal activity over long durations of exposure and after a 3-month storage timeframe. A marginal decrease in heating can be noticed following laundering with traditional detergent cleaners, mainly during the first washing cycle. The coating resistance to washing could be improved by the cross linkage of a biodegradable polymer, chitosan.

Automated summary

The use of silver nanoparticles (AgNPs) for photothermal disinfection of PPE has shown promising results in deactivating the SARS-CoV-2 virus responsible for the COVID-19 pandemic. The AgNP/protectant composites demonstrated monodisperse spherical particles of 5-10 nm in diameter, activated by blue light-emitting diodes to elevate surface temperatures up to 150 degrees C. The photothermal activation was found to be highly efficient and durable over long periods of exposure, with potential improvement in washing resistance through chitosan cross-linking.