期刊
INDIAN JOURNAL OF MEDICAL MICROBIOLOGY
卷 40, 期 1, 页码 156-159出版社
ELSEVIER
DOI: 10.1016/j.ijmmb.2021.11.010
关键词
Cystic fibrosis; Inquilinus limosus co-infection; Neutrophil extracellular traps
类别
资金
- SEP-CONACYT [A1-S-9424]
- Basic Scientific Research 2017-2018 Fund for Education
This study identifies Inquilinus limosus, a rarely reported multidrug resistant bacterium, in cystic fibrosis patients. Co-infection with this bacterium and Pseudomonas aeruginosa promotes increased formation of neutrophil extracellular traps, potentially impacting disease severity and treatment.
Cystic fibrosis is characterized by abnormal mucous secretions in the lungs that favor the proliferation of colonizing bacteria, with Pseudomonas aeruginosa and Staphylococcus aureus being the most isolated, however, other less known species could also have an impact on the health of the patient. Here we demonstrate the isolation and antibiotic resistance profiles of Inquilinus limosus, a rarely reported multidrug resistant bacterium, and compare them to a co-infectant strain of Pseudomonas aeruginosa. Likewise, we found that co-infection with both bacteria promotes increased formation of neutrophil extracellular traps, which can have an impact on the disease severity and make treatment difficult.
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