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Matthew Meredith et al.
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Peripheral regulatory T lymphocytes recirculating to the thymus suppress the development of their precursors
Nicolas Thiault et al.
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Single-cell transcriptome analysis reveals coordinated ectopic gene-expression patterns in medullary thymic epithelial cells
Philip Brennecke et al.
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Thymic B cells and central T cell tolerance
Tomoyoshi Yamano et al.
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Stephen N. Sansom et al.
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Byron B. Au-Yeung et al.
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Distinct phases in the positive selection of CD8+ T cells distinguished by intrathymic migration and T-cell receptor signaling patterns
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D. Nazzal et al.
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Ludger Klein et al.
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Judith N. Mandl et al.
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Stephen R. Daley et al.
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Gretta L. Stritesky et al.
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Charles Sinclair et al.
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Jason Perera et al.
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Heather J. Melichar et al.
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Transcriptome sequencing of neonatal thymic epithelial cells
Charles St-Pierre et al.
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Mara Kornete et al.
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T-Cell Tolerance: Central and Peripheral
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IMPACT OF ENZYMATIC TISSUE DISINTEGRATION ON THE LEVEL OF SURFACE MOLECULE EXPRESSION AND IMMUNE CELL FUNCTION
A. Autengruber et al.
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Nicolas Prevot et al.
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The thymic medulla: a unique microenvironment for intercellular self-antigen transfer
Christian Koble et al.
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Thymus-homing peripheral dendritic cells constitute two of the three major subsets of dendritic cells in the steady-state thymus
JiChu Li et al.
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Impaired CD4 and CD8 Effector Function and Decreased Memory T Cell Populations in ICOS-Deficient Patients
Naomi Takahashi et al.
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Clonal deletion of thymocytes can occur in the cortex with no involvement of the medulla
Tom M. McCaughtry et al.
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A critical role of costimulation during intrathymic development of invariant NK T cells
Yeonseok Chung et al.
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Daniel Hawiger et al.
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ICOS controls the pool size of effector-memory and regulatory T cells
Yvonne Burmeister et al.
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Thymocyte-Dendritic Cell Interactions near Sources of CCR7 Ligands in the Thymic Cortex
Ena Ladi et al.
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The Immunological Genome Project: networks of gene expression in immune cells
Tracy S. P. Heng et al.
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Clonal deletion of thymocytes by circulating dendritic cells homing to the thymus
Roberto Bonasio et al.
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CD4+CD25+ T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion
AE Herman et al.
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Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation
AM Gallegos et al.
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Importance of the inducible costimulator molecule for the induction of allergic immune responses and its decreased expression on T helper cells after venom immunotherapy
I Bellinghausen et al.
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Costimulation through the inducible costimulator ligand is essential for both T helper and B cell functions in T cell-dependent B cell responses
TW Mak et al.
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Constitutive expression of the B7h ligand for inducible costimulator on naive B cells is extinguished after activation by distinct B cell receptor and interleukin 4 receptor-mediated pathways and can be rescued by CD40 signaling
L Liang et al.
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Requirement for a complex array of costimulators in the negative selection of autoreactive thymocytes in vivo
RX Li et al.
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ICOS co-stimulatory receptor is essential for T-cell activation and function
C Dong et al.
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ICOS is essential for effective T-helper-cell responses
A Tafuri et al.
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Mouse inducible costimulatory molecule (ICOS) expression is enhanced by CD28 costimulation and regulates differentiation of CD4+ T cells
AJ McAdam et al.
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