4.2 Article

Association of Flavin Monooxygenase Gene E158K Polymorphism with Chronic Heart Disease Risk

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SPRINGER
DOI: 10.1007/s10517-015-3073-8

关键词

chronic heart disease; flavin-containing monooxygenase 3; association

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  1. Russian Science Foundation [15-15-10010]
  2. Russian Science Foundation [15-15-10010] Funding Source: Russian Science Foundation

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We studied the relationship between the risk of chronic heart disease and FMO3 gene polymorphism E158K analyzed by PCR and restriction fragment length polymorphism (RFLP) analysis. The homozygous 158KK genotype of FMO3 gene is associated with high risk of chronic heart disease in women, but not in men. FMO3 gene polymorphism E158K is a significant predictor of predisposition to chronic heart disease in women.

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