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Gastroenterology & Hepatology
Location-specific cell identity rather than exposure to GI microbiota defines many innate immune signalling cascades in the gut epithelium
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Summary: The study demonstrates extensive spatial organization of innate immune signaling components along the cephalocaudal axis in the GI tract. This organization is largely determined before birth and independent of exposure to commensal gut microbiota. Gastric epithelial organoids can sense LPS from both the basal and apical sides.
GUT (2021)
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Obstetrics & Gynecology
Distribution of Late-Onset Neonatal Sepsis Pathogens Differs in Inpatient and Outpatient Settings
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Novel Segment- and Host-Specific Patterns of Enteroaggregative Escherichia coli Adherence to Human Intestinal Enteroids
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MBIO (2018)
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