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CELL REPORTS (2017)
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CELL REPORTS (2017)
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CELL REPORTS (2017)
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Structural reorganization of the chromatin remodeling enzyme Chd1 upon engagement with nucleosomes
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ELIFE (2017)
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BLOOD (2017)
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CHD4 Has Oncogenic Functions in Initiating and Maintaining Epigenetic Suppression of Multiple Tumor Suppressor Genes
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CANCER CELL (2017)
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CELL (2017)
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DEVELOPMENTAL CELL (2017)
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JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
De Novo Mutations in CHD4, an ATP-Dependent Chromatin Remodeler Gene, Cause an Intellectual Disability Syndrome with Distinctive Dysmorphisms
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Loss of CHD1 causes DNA repair defects and enhances prostate cancer therapeutic responsiveness
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EMBO REPORTS (2016)
The Chromatin Remodelling Protein CHD1 Contains a Previously Unrecognised C-Terminal Helical Domain
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JOURNAL OF MOLECULAR BIOLOGY (2016)
PARP1 Links CHD2-Mediated Chromatin Expansion and H3.3 Deposition to DNA Repair by Non-homologous End-Joining
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MOLECULAR CELL (2016)
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NATURE (2016)
CHD8 haploinsufficiency results in autistic-like phenotypes in mice
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Chd7 cooperates with Sox10 and regulates the onset of CNS myelination and remyelination
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Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signaling
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NATURE NEUROSCIENCE (2016)
Assembly of methylated KDM1A and CHD1 drives androgen receptor-dependent transcription and translocation
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NUCLEIC ACIDS RESEARCH (2016)
Assembly of methylated KDM1A and CHD1 drives androgen receptor-dependent transcription and translocation
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NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
RNAi screens identify CHD4 as an essential gene in breast cancer growth
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ONCOTARGET (2016)
Exome and deep sequencing of clinically aggressive neuroblastoma reveal somatic mutations that affect key pathways involved in cancer progression
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ONCOTARGET (2016)
A Functional Switch of NuRD Chromatin Remodeling Complex Subunits Regulates Mouse Cortical Development
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CELL REPORTS (2016)
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PLOS ONE (2016)
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GENOME BIOLOGY (2016)
Identification of CHD4 As a Potential Therapeutic Target of Acute Myeloid Leukemia
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BLOOD (2016)
CHD4 is associated with poor prognosis of non- small cell lung cancer patients through promoting tumor cell proliferation
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EUROPEAN RESPIRATORY JOURNAL (2016)
Mutations in CHD2 cause defective association with active chromatin in chronic lymphocytic leukemia
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BLOOD (2015)
Depletion of the chromatin remodeler CHD4 sensitizes AML blasts to genotoxic agents and reduces tumor formation
Justin Sperlazza et al.
BLOOD (2015)
Coordinate Loss of MAP3K7 and CHD1 Promotes Aggressive Prostate Cancer
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CANCER RESEARCH (2015)
Constraint of gene expression by the chromatin remodelling protein CHD4 facilitates lineage specification
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DEVELOPMENT (2015)
CHD1 acts via the Hmgpi pathway to regulate mouse early embryogenesis
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DEVELOPMENT (2015)
Chromatin remodeling and bivalent histone modifications in embryonic stem cells
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EMBO REPORTS (2015)
CHD6 regulates the topological arrangement of the CFTR locus
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HUMAN MOLECULAR GENETICS (2015)
New Face for Chromatin-Related Mesenchymal Modulator: n-CHD9 Localizes to Nucleoli and Interacts With Ribosomal Genes
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JOURNAL OF CELLULAR PHYSIOLOGY (2015)
Defeating EpCAM+ liver cancer stem cells by targeting chromatin remodeling enzyme CHD4 in human hepatocellular carcinoma
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JOURNAL OF HEPATOLOGY (2015)
BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors
Dharmendra Dingar et al.
JOURNAL OF PROTEOMICS (2015)
NSD3-Short Is an Adaptor Protein that Couples BRD4 to the CHD8 Chromatin Remodeler
Chen Shen et al.
MOLECULAR CELL (2015)
The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesis
Mark M. Pomerantz et al.
NATURE GENETICS (2015)
ESR1 mutations-a mechanism for acquired endocrine resistance in breast cancer
Rinath Jeselsohn et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2015)
From the genetic architecture to synaptic plasticity in autism spectrum disorder
Thomas Bourgeron
NATURE REVIEWS NEUROSCIENCE (2015)
CHD2 myoclonic encephalopathy is frequently associated with self-induced seizures
Rhys H. Thomas et al.
NEUROLOGY (2015)
Emergence of hematopoietic stem and progenitor cells involves a Chd1-dependent increase in total nascent transcription
Fong Ming Koh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Oncogenesis driven by the Ras/Raf pathway requires the SUMO E2 ligase Ubc9
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomalies
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SCIENCE (2015)
CHD2 is Required for Embryonic Neurogenesis in the Developing Cerebral Cortex
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STEM CELLS (2015)
Chromodomain Helicase DNA-Binding Proteins in Stem Cells and Human Developmental Diseases
Joseph A. Micucci et al.
STEM CELLS AND DEVELOPMENT (2015)
Embryonic stem cell differentiation requires full length Chd1
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SCIENTIFIC REPORTS (2015)
The Chromatin Remodeler CHD8 Is Required for Activation of Progesterone Receptor-Dependent Enhancers
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PLOS GENETICS (2015)
Chromatin Remodelers: From Function to Dysfunction
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GENES (2015)
Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics
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SCIENCE ADVANCES (2015)
The function of chromatin modifiers in lineage commitment and cell fate specification
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FEBS JOURNAL (2015)
Human CHD2 Is a Chromatin Assembly ATPase Regulated by Its Chromo- and DNA-binding Domains
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JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
The Chromatin Regulator CHD8 Is a Context-Dependent Mediator of Cell Survival in Murine Hematopoietic Malignancies
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PLOS ONE (2015)
CHD7 Maintains Neural Stem Cell Quiescence and Prevents Premature Stem Cell Depletion in the Adult Hippocampus
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STEM CELLS (2015)
Emerging mechanisms of resistance to androgen receptor inhibitors in prostate cancer
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Epigenetic Silencing of CHD5, a Novel Tumor-Suppressor Gene, Occurs in Early Colorectal Cancer Stages
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Role of CHD5 in Human Cancers: 10 Years Later
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CHD7 Expression Predicts Survival Outcomes in Patients with Resected Pancreatic Cancer
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CANCER RESEARCH (2014)
Disruptive CHD8 Mutations Define a Subtype of Autism Early in Development
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EPILEPSY & BEHAVIOR (2014)
CHD7 interacts with BMP R-SMADs to epigenetically regulate cardiogenesis in mice
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CHD7 and retinoic acid signaling cooperate to regulate neural stem cell and inner ear development in mouse models of CHARGE syndrome
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The Tumor Suppressor Chromodomain Helicase DNA-binding Protein 5 (CHD5) Remodels Nucleosomes by Unwrapping
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JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
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Inappropriate p53 activation during development induces features of CHARGE syndrome
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Promoter Decommissioning by the NuRD Chromatin Remodeling Complex Triggers Synaptic Connectivity in the Mammalian Brain
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The chromatin remodeller CHD8 is required for E2F-dependent transcription activation of S-phase genes
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The NuRD complex cooperates with DNMTs to maintain silencing of key colorectal tumor suppressor genes
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CHD8 regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitors
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Chd5 orchestrates chromatin remodelling during sperm development
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Recurrent de novo mutations implicate novel genes underlying simplex autism risk
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ZFHX4 Interacts with the NuRD Core Member CHD4 and Regulates the Glioblastoma Tumor-Initiating Cell State
Yakov Chudnovsky et al.
CELL REPORTS (2014)
The nucleosomal barrier to promoter escape by RNA polymerase II is overcome by the chromatin remodeler Chd1
Peter J. Skene et al.
ELIFE (2014)
Frequent Disruption of Chromodomain Helicase DNA-Binding Protein 8 (CHD8) and Functionally Associated Chromatin Regulators in Prostate Cancer
Nathan A. Damaschke et al.
NEOPLASIA (2014)
Identification of miR-26 as a key mediator of estrogen stimulated cell proliferation by targeting CHD1, GREB1 and KPNA2
Sheng Tan et al.
BREAST CANCER RESEARCH (2014)
CHD2 haploinsufficiency is associated with developmental delay, intellectual disability, epilepsy and neurobehavioural problems
Sebastien Chenier et al.
JOURNAL OF NEURODEVELOPMENTAL DISORDERS (2014)
De Novo Loss-of-Function Mutations in CHD2 Cause a Fever-Sensitive Myoclonic Epileptic Encephalopathy Sharing Features with Dravet Syndrome
Arvid Suls et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2013)
CHD1 Is a 5q21 Tumor Suppressor Required for ERG Rearrangement in Prostate Cancer
Lia Burkhardt et al.
CANCER RESEARCH (2013)
Glucocorticoid Receptor Confers Resistance to Antiandrogens by Bypassing Androgen Receptor Blockade
Vivek K. Arora et al.
CELL (2013)
Mechanisms and Functions of ATP-Dependent Chromatin-Remodeling Enzymes
Geeta J. Narlikar et al.
CELL (2013)
Punctuated Evolution of Prostate Cancer Genomes
Sylvan C. Baca et al.
CELL (2013)
The Chromatin Remodeler CHD7 Regulates Adult Neurogenesis via Activation of SoxC Transcription Factors
Weijun Feng et al.
CELL STEM CELL (2013)
CHD5 Is Required for Neurogenesis and Has a Dual Role in Facilitating Gene Expression and Polycomb Gene Repression
Chris M. Egan et al.
DEVELOPMENTAL CELL (2013)
The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation
Anke Sparmann et al.
EMBO JOURNAL (2013)
A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal
Alessia Gagliardi et al.
EMBO JOURNAL (2013)
Nucleosome sliding by Chd1 does not require rigid coupling between DNA-binding and ATPase domains
Ilana M. Nodelman et al.
EMBO REPORTS (2013)
A double take on bivalent promoters
Philipp Voigt et al.
GENES & DEVELOPMENT (2013)
CHD chromatin remodelling enzymes and the DNA damage response
Fintan K. T. Stanley et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2013)
Deterministic direct reprogramming of somatic cells to pluripotency
Yoach Rais et al.
NATURE (2013)
Targeted resequencing in epileptic encephalopathies identifies de novo mutations in CHD2 and SYNGAP1
Gemma L. Carvill et al.
NATURE GENETICS (2013)
From neural development to cognition: unexpected roles for chromatin
Jehnna L. Ronan et al.
NATURE REVIEWS GENETICS (2013)
Nucleosome sliding mechanisms: new twists in a looped history
Felix Mueller-Planitz et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)
CHD8 is an independent prognostic indicator that regulates Wnt/β-catenin signaling and the cell cycle in gastric cancer
Genta Sawada et al.
ONCOLOGY REPORTS (2013)
NuRD Blocks Reprogramming of Mouse Somatic Cells into Pluripotent Stem Cells
Min Luo et al.
STEM CELLS (2013)
Chd5 Requires PHD-Mediated Histone 3 Binding for Tumor Suppression
Shilpi Paul et al.
CELL REPORTS (2013)
Chromatin Remodeling Enzyme CHD7 Negatively Regulate Hematopoietic Stem Cell Function
Jingmei Hsu et al.
BLOOD (2013)
The Mutation in Chd7 Causes Misexpression of Bmp4 and Developmental Defects in Telencephalic Midline
Xuan Jiang et al.
AMERICAN JOURNAL OF PATHOLOGY (2012)
NuRD and Pluripotency: A Complex Balancing Act
Guang Hu et al.
CELL STEM CELL (2012)
NuRD Suppresses Pluripotency Gene Expression to Promote Transcriptional Heterogeneity and Lineage Commitment
Nicola Reynolds et al.
CELL STEM CELL (2012)
Chd2 interacts with H3.3 to determine myogenic cell fate
Akihito Harada et al.
EMBO JOURNAL (2012)
Chromodomain helicase DNA-binding protein 2 affects the repair of X-ray and UV-Induced DNA damage
Sangeetha Rajagopalan et al.
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS (2012)
Deletion of the RMGA and CHD2 genes in a child with epilepsy and mental deficiency
Leonardo P. Capelli et al.
EUROPEAN JOURNAL OF MEDICAL GENETICS (2012)
Concerted action of the PHD, chromo and motor domains regulates the human chromatin remodelling ATPase CHD4
Rosa Morra et al.
FEBS LETTERS (2012)
Identification of CHD7S as a novel splicing variant of CHD7 with functions similar and antagonistic to those of the full-length CHD7L
Yasuyuki Kita et al.
GENES TO CELLS (2012)
Chromodomain Helicase DNA-binding Protein 4 (CHD4) Regulates Homologous Recombination DNA Repair, and Its Deficiency Sensitizes Cells to Poly(ADP-ribose) Polymerase (PARP) Inhibitor Treatment
Mei-Ren Pan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
The PHD and Chromo Domains Regulate the ATPase Activity of the Human Chromatin Remodeler CHD4
Aleksandra A. Watson et al.
JOURNAL OF MOLECULAR BIOLOGY (2012)
The Nucleosome Remodeling and Deacetylase Chromatin Remodeling (NuRD) Complex Is Required for Peripheral Nerve Myelination
Holly Hung et al.
JOURNAL OF NEUROSCIENCE (2012)
Histone H1 Recruitment by CHD8 Is Essential for Suppression of the Wnt-beta-Catenin Signaling Pathway
Masaaki Nishiyama et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
MBD2 and Multiple Domains of CHD4 Are Required for Transcriptional Repression by Mi-2/NuRD Complexes
Julita Ramirez et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
Range of genetic mutations associated with severe non-syndromic sporadic intellectual disability: an exome sequencing study
Anita Rauch et al.
LANCET (2012)
Suppression of the antiviral response by an influenza histone mimic
Ivan Marazzi et al.
NATURE (2012)
Enhancer decommissioning by LSD1 during embryonic stem cell differentiation
Warren A. Whyte et al.
NATURE (2012)
The mutational landscape of lethal castration-resistant prostate cancer
Catherine S. Grasso et al.
NATURE (2012)
De novo mutations revealed by whole-exome sequencing are strongly associated with autism
Stephan J. Sanders et al.
NATURE (2012)
Topological domains in mammalian genomes identified by analysis of chromatin interactions
Jesse R. Dixon et al.
NATURE (2012)
Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations
Brian J. O'Roak et al.
NATURE (2012)
Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia
Victor Quesada et al.
NATURE GENETICS (2012)
Identification of novel CHD1-associated collaborative alterations of genomic structure and functional assessment of CHD1 in prostate cancer
W. Liu et al.
ONCOGENE (2012)
Recurrent deletion of CHD1 in prostate cancer with relevance to cell invasiveness
S. Huang et al.
ONCOGENE (2012)
The chromatin remodeling complex NuRD establishes the poised state of rRNA genes characterized by bivalent histone modifications and altered nucleosome positions
Wenbing Xie et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Bivalent recognition of nucleosomes by the tandem PHD fingers of the CHD4 ATPase is required for CHD4-mediated repression
Catherine A. Musselman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Chromatin remodeling by the CHD7 protein is impaired by mutations that cause human developmental disorders
Karim Bouazoune et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
A SUMOylation-Dependent Transcriptional Subprogram Is Required for Myc-Driven Tumorigenesis
Jessica D. Kessler et al.
SCIENCE (2012)
Multiplex Targeted Sequencing Identifies Recurrently Mutated Genes in Autism Spectrum Disorders
Brian J. O'Roak et al.
SCIENCE (2012)
The Drosophila Mi-2 Chromatin-Remodeling Factor Regulates Higher-Order Chromatin Structure and Cohesin Dynamics In Vivo
Barbara Fasulo et al.
PLOS GENETICS (2012)
Cell of origin strongly influences genetic selection in a mouse model of T-ALL
Katherine E. Berquam-Vrieze et al.
BLOOD (2011)
Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development
Philip J. Stephens et al.
CELL (2011)
Mbd3/NURD Complex Regulates Expression of 5-Hydroxymethylcytosine Marked Genes in Embryonic Stem Cells
Ozlem Yildirim et al.
CELL (2011)
Chromatin Connections to Pluripotency and Cellular Reprogramming
Stuart H. Orkin et al.
CELL (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
The TWIST/Mi2/NuRD protein complex and its essential role in cancer metastasis
Junjiang Fu et al.
CELL RESEARCH (2011)
Snf2-family proteins: chromatin remodellers for any occasion
Daniel P. Ryan et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2011)
Structural insights into regulation and action of SWI2/SNF2 ATPases
Glenn Hauk et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2011)
The DNA-binding domain of the Chd1 chromatin-remodelling enzyme contains SANT and SLIDE domains
Daniel P. Ryan et al.
EMBO JOURNAL (2011)
Mediator coordinates PIC assembly with recruitment of CHD1
Justin J. Lin et al.
GENES & DEVELOPMENT (2011)
Plant Homeodomain (PHD) Fingers of CHD4 Are Histone H3-binding Modules with Preference for Unmodified H3K4 and Methylated H3K9
Robyn E. Mansfield et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Extranucleosomal DNA Binding Directs Nucleosome Sliding by Chd1
Jeffrey N. McKnight et al.
MOLECULAR AND CELLULAR BIOLOGY (2011)
The genomic complexity of primary human prostate cancer
Michael F. Berger et al.
NATURE (2011)
esBAF facilitates pluripotency by conditioning the genome for LIF/STAT3 signalling and by regulating polycomb function
Lena Ho et al.
NATURE CELL BIOLOGY (2011)
Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes
Erik Engelen et al.
NATURE GENETICS (2011)
KAP-1 phosphorylation regulates CHD3 nucleosome remodeling during the DNA double-strand break response
Aaron A. Goodarzi et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)
Stress-Induced PARP Activation Mediates Recruitment of Drosophila Mi-2 to Promote Heat Shock Gene Expression
Magdalena Murawska et al.
PLOS GENETICS (2011)
Cancer biology and NuRD: a multifaceted chromatin remodelling complex
Anne Y. Lai et al.
NATURE REVIEWS CANCER (2011)
An Expanded Oct4 Interaction Network: Implications for Stem Cell Biology, Development, and Disease
Mercedes Pardo et al.
CELL STEM CELL (2010)
The ATP-dependent chromatin remodeling enzyme CHD7 regulates pro-neural gene expression and neurogenesis in the inner ear
Elizabeth A. Hurd et al.
DEVELOPMENT (2010)
Nucleosome positioning: How is it established, and why does it matter?
Marta Radman-Livaja et al.
DEVELOPMENTAL BIOLOGY (2010)
Regulation of HOXA2 gene expression by the ATP-dependent chromatin remodeling enzyme CHD8
Joel A. Yates et al.
FEBS LETTERS (2010)
Transcriptional silencing of γ-globin by BCL11A involves long-range interactions and cooperation with SOX6
Jian Xu et al.
GENES & DEVELOPMENT (2010)
CHD8 interacts with CHD7, a protein which is mutated in CHARGE syndrome
Tserendulam Batsukh et al.
HUMAN MOLECULAR GENETICS (2010)
CHD7 functions in the nucleolus as a positive regulator of ribosomal RNA biogenesis
Gabriel E. Zentner et al.
HUMAN MOLECULAR GENETICS (2010)
The Chromodomains of the Chd1 Chromatin Remodeler Regulate DNA Access to the ATPase Motor
Glenn Hauk et al.
MOLECULAR CELL (2010)
Regulation of Androgen-Responsive Transcription by the Chromatin Remodeling Factor CHD8
Tushar Menon et al.
MOLECULAR ENDOCRINOLOGY (2010)
Deletion of the Chd6 exon 12 affects motor coordination
Melissa J. Lathrop et al.
MAMMALIAN GENOME (2010)
CHD7 cooperates with PBAF to control multipotent neural crest formation
Ruchi Bajpai et al.
NATURE (2010)
Functional impact of global rare copy number variation in autism spectrum disorders
Dalila Pinto et al.
NATURE (2010)
CHD7 Targets Active Gene Enhancer Elements to Modulate ES Cell- Specific Gene Expression
Michael P. Schnetz et al.
PLOS GENETICS (2010)
The Biology of Chromatin Remodeling Complexes
Cedric R. Clapier et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2009)
Expression of the Dermatomyositis Autoantigen Mi-2 in Regenerating Muscle
Andrew L. Mammen et al.
ARTHRITIS AND RHEUMATISM (2009)
LSD1 Is a Subunit of the NuRD Complex and Targets the Metastasis Programs in Breast Cancer
Yan Wang et al.
CELL (2009)
Transcriptional competence in pluripotency
Edupuganti V. S. Raghu Ram et al.
GENES & DEVELOPMENT (2009)
Genomic distribution of CHD7 on chromatin tracks H3K4 methylation patterns
Michael P. Schnetz et al.
GENOME RESEARCH (2009)
Estrogen Regulation of Cyclin E2 Requires Cyclin D1 but Not c-Myc
C. Elizabeth Caldon et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Chd1 regulates open chromatin and pluripotency of embryonic stem cells
Alexandre Gaspar-Maia et al.
NATURE (2009)
CHD8 suppresses p53-mediated apoptosis through histone H1 recruitment during early embryogenesis
Masaaki Nishiyama et al.
NATURE CELL BIOLOGY (2009)
Chromatin organization marks exon-intron structure
Schraga Schwartz et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
The chromatin remodeling factor CHD8 interacts with elongating RNA polymerase II and controls expression of the cyclin E2 gene
M. Rodriguez-Paredes et al.
NUCLEIC ACIDS RESEARCH (2009)
Role of chromodomain helicase DNA-binding protein 2 in DNA damage response signaling and tumorigenesis
P. Nagarajan et al.
ONCOGENE (2009)
Opposing effects of SWI/SNF and Mi-2/NuRD chromatin remodeling complexes on epigenetic reprogramming by EBF and Pax5
Hua Gao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency
Lena Ho et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
Chunaram Choudhary et al.
SCIENCE (2009)
Disruption of chromodomain helicase DNA binding protein 2 (CHD2) causes scoliosis
Shashikant Kulkarni et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2008)
An extended transcriptional network for pluripotency of embryonic stem cells (vol 132, pg 1049, 2008)
Jonghwan Kim et al.
CELL (2008)
Global transcription in pluripotent embryonic stem cells
Sol Efroni et al.
CELL STEM CELL (2008)
The role of the chromatin remodeler Mi-2β in hematopoietic stem cell self-renewal and multilineage differentiation
Toshimi Yoshida et al.
GENES & DEVELOPMENT (2008)
A Mutation in the Mouse Chd2 Chromatin Remodeling Enzyme Results in a Complex Renal Phenotype
Concetta G. A. Marfella et al.
KIDNEY & BLOOD PRESSURE RESEARCH (2008)
MBD3, a component of the NuRD complex, facilitates chromatin alteration and deposition of epigenetic marks
Lluis Morey et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
BAT3 and SET1A Form a Complex with CTCFL/BORIS To Modulate H3K4 Histone Dimethylation and Gene Expression
Phuongmai Nguyen et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Essential Role of Chromatin Remodeling Protein Bptf in Early Mouse Embryos and Embryonic Stem Cells
Joseph Landry et al.
PLOS GENETICS (2008)
Drosophila Kismet Regulates Histone H3 Lysine 27 Methylation and Early Elongation by RNA Polymerase II
Shrividhya Srinivasan et al.
PLOS GENETICS (2008)
Recognition of trimethylated histone h3 lysine 4 facilitates the recruitment of transcription postinitiation factors and pre-mRNA splicing
Robert J. Sims et al.
MOLECULAR CELL (2007)
Antagonistic interactions between lkaros and the chromatin remodeler Mi-2β determine silencer activity and Cd4 gene expression
Taku Naito et al.
IMMUNITY (2007)
Rtf1 is a multifunctional component of the paf1 complex that regulates gene expression by directing cotranscriptional histone modification
Marcie H. Warner et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Solution structure of the BRK domains from CHD7
Mark D. Allen et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
CHD1 motor protein is required for deposition of histone variant h3.3 into chromatin in vivo
Alexander Y. Konev et al.
SCIENCE (2007)
Molecular implications of evolutionary differences in CHD double chromodomains
John F. Flanagan et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
A new paradigm for developmental biology
John S. Mattick
JOURNAL OF EXPERIMENTAL BIOLOGY (2007)
The Chd family of chromatin remodelers
Concetta G. A. Marfella et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2007)
The chromatin remodeler Mi-2β is required for establishment of the basal epidermis and normal differentiation of its progeny
Mariko Kashiwagi et al.
DEVELOPMENT (2007)
The role of chromatin during transcription
Bing Li et al.
CELL (2007)
CHD6 is a DNA-dependent ATPase and localizes at nuclear sites of mRNA synthesis
Thomas Lutz et al.
FEBS LETTERS (2006)
Mutation of the SNF2 family member Chd2 affects mouse development and survival
Concetta G. A. Marfella et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2006)
CTCF-dependent chromatin insulator is linked to epigenetic remodeling
Ko Ishihara et al.
MOLECULAR CELL (2006)
Unique risk factors for insertional mutagenesis in a mouse model of XSCID gene therapy
Yan Shou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Analysis of nucleosome repositioning by yeast ISWI and Chd1 chromatin remodeling complexes
Chris Stockdale et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
NAB2 represses transcription by interacting with the CHD4 subunit of the nucleosome remodeling and deacetylase (NuRD) complex
Rajini Srinivasan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Expression and regulation of CReMM, a chromodomain helicase-DNA-binding (CHD), in marrow strorna derived osteoprogenitors
R Marom et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2006)
PRIC320, a transcription coactivator, isolated from peroxisome proliferator-binding protein complex
S Surapureddi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
In vivo association of CReMM/CHD9 with promoters in osteogenic cells
I Shur et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2006)
Dynamic interactions of chromatin-related mesenchymal modulator, a chromodomain helicase-DNA-binding protein, with promoters in osteoprogenitors
Irena Shur et al.
STEM CELLS (2006)
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
BE Bernstein et al.
CELL (2006)
CTCF mediates interchromosomal colocalization between Igf2/H19 and Wsb1/Nf1
JQ Ling et al.
SCIENCE (2006)
Metastasis-associated protein 1 enhances stability of hypoxia-inducible factor-1α protein by recruiting histone deacetylase 1
YG Yoo et al.
EMBO JOURNAL (2006)
The NuRD component Mbd3 is required for pluripotency of embryonic stem cells
K Kaji et al.
NATURE CELL BIOLOGY (2006)
Suppression of STAT3 activity by duplin, which is a negative regulator of the Wnt signal
K Yamashina et al.
JOURNAL OF BIOCHEMISTRY (2006)
Selective and antagonistic functions of SWI/SNF and Mi-2β nucleosome remodeling complexes during an inflammatory response
VR Ramirez-Carrozzi et al.
GENES & DEVELOPMENT (2006)
Identification of multiple distinct Snf2 subfamilies with conserved structural motifs
Andrew Flaus et al.
NUCLEIC ACIDS RESEARCH (2006)
The human SWI/SNF subunit Brm is a regulator of alternative splicing
E Batsche et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2006)
Human but not yeast CHD1 binds directly and selectively to histone H3 methylated at lysine 4 via its tandem chromodomains
RJ Sims et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Double chromodomains cooperate to recognize the methylated histone H3 tail
JF Flanagan et al.
NATURE (2005)
Characterization and functional analysis of CReMM, a novel chromodomain helicase DNA-binding protein
I Shur et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
The Drosophila trithorax group protein Kismet facilitates an early step in transcriptional elongation by RNA Polymerase II
S Srinivasan et al.
DEVELOPMENT (2005)
Distinct activities of CHD1 and ACF in ATP-dependent chromatin assembly
A Lusser et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2005)
The SANT domain: a unique histone-tail-binding module?
LA Boyer et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
MTA3 and the Mi-2/NuRD complex regulate cell fate during B lymphocyte differentiation
N Fujita et al.
CELL (2004)
The chromatin remodeler Mi-2β is required for CD4 expression and T cell development
CJ Williams et al.
IMMUNITY (2004)
Early embryonic death in mice lacking the β-catenin-binding protein duplin
M Nishiyama et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
MTA3, a Mi-2/NuRD complex subunit, an invasive growth pathway in breast
N Fujita et al.
CELL (2003)
Chromatin remodeling protein Chd1 interacts with transcription elongation factors and localizes to transcribed genes
R Simic et al.
EMBO JOURNAL (2003)
SATB1 targets chromatin remodelling to regulate genes over long distances
D Yasui et al.
NATURE (2002)
RNA polymerase II elongation factors of Saccharomyces cerevisiae:: a targeted proteomnics approach
NJ Krogan et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Identification of a transcriptionally active peroxisome proliferator-activated receptor α-interacting cofactor complex in rat liver and characterization of PRIC285 as a coactivator
S Surapureddi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
High-throughput retroviral tagging to identify components of specific signaling pathways in cancer
H Mikkers et al.
NATURE GENETICS (2002)
CHD5 defines a new subfamily of chromodomain-SWI2/SNF2-like helicases
EF Schuster et al.
MAMMALIAN GENOME (2002)
Mi2, an auto-antigen for dermatomyositis, is an ATP-dependent nucleosome remodeling factor
HB Wang et al.
NUCLEIC ACIDS RESEARCH (2001)
Deacetylation of p53 modulates its effect on cell growth and apoptosis
JY Luo et al.
NATURE (2000)
A novel β-catenin-binding protein inhibits β-catenin-dependent Tcf activation and axis formation
I Sakamoto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Chromodomains are protein-RNA interaction modules
A Akhtar et al.
NATURE (2000)
dMi-2 and ISWI chromatin remodelling factors have distinct nucleosome binding and mobilization properties
A Brehm et al.
EMBO JOURNAL (2000)