4.7 Review

Comparative diagnostic performance of end-cutting fine-needle biopsy needles for EUS tissue sampling of solid pancreatic masses: a network meta-analysis

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Randomized trial comparing the 25G and 22G Franseen needles in endoscopic ultrasound-guided tissue acquisition from solid pancreatic masses for adequate histological assessment

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Summary: This study compared the performance of 25G and 22G Franseen needles in obtaining tissue from solid pancreatic masses, with the 25G needle showing noninferiority in tissue acquisition and similar diagnostic accuracy to the 22G needle. However, further consideration may be needed regarding the 15% noninferiority margin for clinical use.

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Summary: The study found that samples collected by fine-needle biopsy using the franseen or fork-tip needle had higher cellularity and diagnostic accuracy compared to other needles, providing better identification of malignant tumors.

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Comparison of endoscopic ultrasound-guided fine-needle biopsy versus fine-needle aspiration for genomic profiling and DNA yield in pancreatic cancer: a randomized crossover trial

Pujan Kandel et al.

Summary: This study compared the adequacy of tissue specimens and DNA yield for genomic profiling between EUS-FNB and EUS-FNA, finding that the adequacy for genomic profiling and DNA yield were significantly higher with the FNB needle compared to the FNA needle.

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Randomized controlled trial comparing the Franseen needle with the Fork-tip needle for EUS-guided fine-needle biopsy

Munish Ashat et al.

Summary: This study compared two commonly used EUS-FNB needles in their ability to provide histologic tissue samples and reach an accurate diagnosis, and found no significant difference in performance between the Franseen needle and the Fork-tip needle. Both needles achieved high yield of histologic tissue samples and high diagnostic accuracy.

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Sho Mizukawa et al.

Summary: The study found that using a Menghini-type needle for EUS-FNA resulted in significantly higher sample quality compared to using a conventional needle. Tumor size and type of needle were significant factors associated with adequate tissue collection. The diagnostic accuracy was 88.7% with needle M and 73.2% with needle S, with a low rate of adverse events (0.02%).

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Comparative diagnostic accuracy of EUS needles in solid pancreatic masses: a network meta-analysis

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Summary: Based on a network meta-analysis, FNB needles demonstrate superior diagnostic performance in sampling pancreatic masses compared to FNA needles, with 22G FNB needles showing the highest performance.

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Comparison between EUS-guided fine-needle aspiration cytology and EUS-guided fine-needle biopsy histology for the evaluation of pancreatic neuroendocrine tumors

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A comparison between 25-gauge and 22-gauge Franseen needles for endoscopic ultrasound-guided sampling of pancreatic and peripancreatic masses: a randomized non-inferiority study

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Summary: This study compared the performance of 25G and 22G Franseen needles for EUS-guided sampling of pancreatic and peripancreatic solid masses. The results showed that the 22G needle was superior to the 25G needle in histologic core procurement, with higher quality specimens obtained in the 22G group. Therefore, for cases where tissue architecture is crucial for diagnosis, a 22G needle should be preferred.

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Summary: The study found that in evaluating solid pancreatic lesions, EUS-FNB without ROSE can achieve high diagnostic accuracy. EUS-FNB without ROSE showed higher tissue core rate and shorter sampling time. Therefore, when using new-generation FNB needles, ROSE should not be routinely recommended.

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Diagnostic yield of endoscopic ultrasound-guided tissue acquisition in autoimmune pancreatitis: a systematic review and meta-analysis

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EUS-guided fine needle biopsy of pancreatic masses can yield true histology

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