4.2 Article

Surface modification of graphene sheets with aluminum phthalocyanine complex

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TAYLOR & FRANCIS INC
DOI: 10.1080/1536383X.2021.1976754

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Graphene-AlClPc systems; oxygen-free graphene; sonochemistry; vibrational spectroscopy of graphene-containing structures; UV-Vis absorption spectroscopy; photodynamic therapy agents

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The study utilized the unique physical properties of graphene to stabilize the AlClPc complex and prevent its agglomeration, while also developing a sonochemical method for preparing stable suspensions of oxygen-free graphene. By employing molecular design techniques, hybrid structures based on AlClPc and graphene were successfully synthesized, leading to new possibilities for drug delivery and early diagnosis platforms.
Recently, it has become more and more obvious that the use of the unique physical properties of graphene is practically inexhaustible. In our work, we used the surface of oxygen-free graphene sheets to stabilize the AlClPc complex and prevent its agglomeration. A sonochemical method was developed for the preparation of stable suspensions of oxygen-free graphene in a DMF-aqua mixture, the composition and morphology of which were characterized using TEM, DLS, and Raman. Also, a method for the synthesis of hybrid structures based on AlClPc and graphene was developed, and new electrons interactions in them were determined by using of UV-VIS absorption spectroscopy. It was proved that these interactions are due to the graphene participation in surface complex with charge transfer. Graphene also prevents the agglomeration of the AlClPc complex, which is especially valuable for using the synthesized structure in biomedical research. The results obtained show how the use of molecular design techniques makes it possible to create new platforms for vector drag delivery and early diagnosis.

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