4.7 Article

Cloning and characterization of a key enzyme in octopaminergic pathway: Tyramine beta-hydroxylase from Litopenaeus vannamei, as expressed during Vibrio alginolytics infection and hypothermal stress

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Summary: In Litopenaeus vannamei, the cloned LvTDC gene is responsible for the synthesis of octopamine, regulating physiological and immune responses. Knockdown of LvTDC resulted in significant decreases in immune function and physiological parameters, indicating the crucial role of LvTDC in maintaining homeostasis in shrimp.LvTDC knockdown shrimp also showed reduced survival rates in a Vibrio alginolyticus challenge test compared to control groups.

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