4.5 Article

Mutation of the conserved Asp-Asp pair impairs the structure, function, and inhibition of CTX-M Class A β-lactamase

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Multidisciplinary Sciences

Mechanism of proton transfer in class A β-lactamase catalysis and inhibition by avibactam

Orville A. Pemberton et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Biochemistry & Molecular Biology

Antagonism between substitutions in ?-lactamase explains a path not taken in the evolution of bacterial drug resistance

Cameron A. Brown et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2020)

Article Microbiology

Active-Site Protonation States in an Acyl-Enzyme Intermediate of a Class A β-Lactamase with a Monobactam Substrate

Venu Gopal Vandavasi et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2017)

Article Biochemistry & Molecular Biology

Short Carboxylic Acid-Carboxylate Hydrogen Bonds Can Have Fully Localized Protons

Jiusheng Lin et al.

BIOCHEMISTRY (2017)

Article Chemistry, Medicinal

Molecular Basis of Substrate Recognition and Product Release by the Klebsiella pneumoniae Carbapenemase (KPC-2)

Orville A. Pemberton et al.

JOURNAL OF MEDICINAL CHEMISTRY (2017)

Article Chemistry, Multidisciplinary

Prediction of New Stabilizing Mutations Based on Mechanistic Insights from Markov State Models

Maxwell I. Zimmerman et al.

ACS CENTRAL SCIENCE (2017)

Article Chemistry, Multidisciplinary

The Low Barrier Hydrogen Bond in the Photoactive Yellow Protein: A Vacuum Artifact Absent in the Crystal and Solution

Timo Graen et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)

Article Multidisciplinary Sciences

Modelling proteins' hidden conformations to predict antibiotic resistance

Kathryn M. Hart et al.

NATURE COMMUNICATIONS (2016)

Article Chemistry, Multidisciplinary

Determination of Hydrogen Bond Structure in Water versus Aprotic Environments To Test the Relationship Between Length and Stability

Paul A. Sigala et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)

Article Chemistry, Multidisciplinary

Ligand-Induced Proton Transfer and Low-Barrier Hydrogen Bond Revealed by X-ray Crystallography

Derek A. Nichols et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)

Article Biochemistry & Molecular Biology

Kinetic and Structural Requirements for Carbapenemase Activity in GES-Type β-Lactamases

Nichole K. Stewart et al.

BIOCHEMISTRY (2015)

Article Biochemistry & Molecular Biology

Strong, Low-Barrier Hydrogen Bonds May Be Available to Enzymes

Jacob D. Graham et al.

BIOCHEMISTRY (2014)

Article Chemistry, Multidisciplinary

Using Unnatural Amino Acids to Probe the Energetics of Oxyanion Hole Hydrogen Bonds in the Ketosteroid Isomerase Active Site

Aditya Natarajan et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)

Article Biochemical Research Methods

Phaser.MRage: automated molecular replacement

Gabor Bunkoczi et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2013)

Article Chemistry, Multidisciplinary

Hyperstability and Substrate Promiscuity in Laboratory Resurrections of Precambrian β-Lactamases

Valeria A. Risso et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)

Article Chemistry, Medicinal

Structure-Based Design of Potent and Ligand-Efficient Inhibitors of CTX-M Class A β-Lactamase

Derek A. Nichols et al.

JOURNAL OF MEDICINAL CHEMISTRY (2012)

Article Multidisciplinary Sciences

Energetics of short hydrogen bonds in photoactive yellow protein

Keisuke Saito et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Biochemical Research Methods

Features and development of Coot

P. Emsley et al.

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)

Article Biochemistry & Molecular Biology

The catalytic efficiency (kcat/Km) of the class A β-lactamase Toho-1 correlates with the thermal stability of its catalytic intermediate analog

Yasushi Nitanai et al.

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2010)

Article Biochemistry & Molecular Biology

Structural Insights into Substrate Recognition and Product Expulsion in CTX-M Enzymes

Julien Delmas et al.

JOURNAL OF MOLECULAR BIOLOGY (2010)

Article Chemistry, Multidisciplinary

An Antibiotic-Resistance Enzyme from a Deep-Sea Bacterium

Marta Toth et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)

Article Biochemistry & Molecular Biology

Molecular docking and ligand specificity in fragment-based inhibitor discovery

Yu Chen et al.

NATURE CHEMICAL BIOLOGY (2009)

Article Biochemistry & Molecular Biology

Re-examining the role of Lys67 in class C β-lactamase catalysis

Yu Chen et al.

PROTEIN SCIENCE (2009)

Article Biochemical Research Methods

Short strong hydrogen bonds in proteins: a case study of rhamnogalacturonan acetylesterase

Annette Langkilde et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2008)

Article Biochemistry & Molecular Biology

Structure and dynamics of CTX-M enzymes reveal insights into substrate accommodation by extended-spectrum β-lactamases

Julien Delmas et al.

JOURNAL OF MOLECULAR BIOLOGY (2008)

Article Biochemistry & Molecular Biology

Genetic and Structural Characterization of an L201 P Global Suppressor Substitution in TEM-1 β-Lactamase

David C. Marciano et al.

JOURNAL OF MOLECULAR BIOLOGY (2008)

Article Chemistry, Multidisciplinary

Phaser crystallographic software

Airlie J. McCoy et al.

JOURNAL OF APPLIED CRYSTALLOGRAPHY (2007)

Article Biochemistry & Molecular Biology

Crystal structure of KPC-2:: Insights into carbapenemase activity in class a β-lactamases

Wei Ke et al.

BIOCHEMISTRY (2007)

Article Chemistry, Multidisciplinary

The acylation mechanism of CTX-M β-lactamase at 0.88 Å resolution

Yu Chen et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)

Article Multidisciplinary Sciences

Crystal structure of HIV-1 protease in situ product complex and observation of a low-barrier hydrogen bond between catalytic aspartates

Amit Das et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Chemistry, Multidisciplinary

Ab initio QM/MM study of class A β-lactamase acylation:: Dual participation of Glu166 and Lys73 in a concerted base promotion of Ser70

SO Meroueh et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)

Article Biochemistry & Molecular Biology

Structural consequences of the inhibitor-resistant Ser130Gly substitution in TEM-lactamase

VL Thomas et al.

BIOCHEMISTRY (2005)

Article Chemistry, Multidisciplinary

Structure, function, and inhibition along the reaction coordinate of CTX-M β-lactamases

Y Chen et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)

Review Microbiology

Growing group of extended-spectrum beta-lactamases: The CTX-M enzymes

R Bonnet

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2004)

Article Biochemistry & Molecular Biology

The low barrier hydrogen bond (LBHB) proposal revisited: The case of the asp... his pair in serine proteases

CN Schutz et al.

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2004)

Article Biochemistry & Molecular Biology

Structural bases of stability-function tradeoffs in enzymes

BM Beadle et al.

JOURNAL OF MOLECULAR BIOLOGY (2002)

Article Microbiology

Molecular analysis of beta-lactamase structure and function

FK Majiduddin et al.

INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY (2002)

Article Biochemistry & Molecular Biology

Evolution of an antibiotic resistance enzyme constrained by stability and activity trade-offs

XJ Wang et al.

JOURNAL OF MOLECULAR BIOLOGY (2002)

Article Chemistry, Multidisciplinary

An ultrahigh resolution structure of TEM-1 β-lactamase suggests a role for Glu166 as the general base in acylation

G Minasov et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)

Article Biochemistry & Molecular Biology

More hydrogen bonds for the (structural) biologist

MS Weiss et al.

TRENDS IN BIOCHEMICAL SCIENCES (2001)

Article Multidisciplinary Sciences

Protonation of the β-lactam nitrogen is the trigger event in the catalytic action of class A β-lactamases

BP Atanasov et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)