4.6 Article

Biophysical investigation of the dual binding surfaces of human transcription factors FOXO4 and p53

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

FOXO4 Transactivation Domain Interaction with Forkhead DNA Binding Domain and Effect on Selective DNA Recognition for Transcription Initiation

Jinwoo Kim et al.

Summary: The TAD and FHD of FOXO4 form an intramolecular complex primarily governed by hydrophobic interactions, sharing the same surface for DNA binding; The FHD-TAD complex exhibits different exchange rates with target and non-target DNA, affecting the kinetic function of FHD; TAD modulates the recognition of target promoter DNA sequences by FOXO4, providing a new kinetic perspective on target sequence selection by transcription factors.

JOURNAL OF MOLECULAR BIOLOGY (2021)

Review Biotechnology & Applied Microbiology

Therapeutic strategies targeting FOXO transcription factors

Giampaolo Calissi et al.

Summary: FOXO proteins are transcription factors that are involved in regulating stress responses to maintain cellular homeostasis. Dysregulation of FOXO protein functions contributes to cardiovascular disease, cancer, diabetes, and neurological diseases. This review summarizes the biology of FOXO proteins, their roles in disease and longevity, and discusses pharmacological approaches to develop FOXO-targeting therapeutics.

NATURE REVIEWS DRUG DISCOVERY (2021)

Article Biotechnology & Applied Microbiology

Cooperative binding of transcription factors in the human genome

Yumin Nie et al.

GENOMICS (2020)

Article Multidisciplinary Sciences

Interaction between p53 N terminus and core domain regulates specific and nonspecific DNA binding

Fan He et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Article Biochemistry & Molecular Biology

NMR characterization of solvent accessibility and transient structure in intrinsically disordered proteins

Christoph Hartlmueller et al.

JOURNAL OF BIOMOLECULAR NMR (2019)

Review Cell Biology

Senescence and aging: Causes, consequences, and therapeutic avenues

Domhnall McHugh et al.

JOURNAL OF CELL BIOLOGY (2018)

Review Biochemistry & Molecular Biology

Regulation of cellular senescence via the FOXO4-p53 axis

Benjamin Bourgeois et al.

FEBS LETTERS (2018)

Article Multidisciplinary Sciences

Long-range regulation of p53 DNA binding by its intrinsically disordered N-terminal transactivation domain

Alexander S. Krois et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Article Biochemistry & Molecular Biology

Tardigrades Use Intrinsically Disordered Proteins to Survive Desiccation

Thomas C. Boothby et al.

MOLECULAR CELL (2017)

Article Multidisciplinary Sciences

Weak protein-protein interactions in live cells are quantified by cell-volume modulation

Shahar Sukenik et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Review Cell Biology

Cell adaptation upon stress: the emerging role of membrane-less compartments

Catherine Rabouille et al.

CURRENT OPINION IN CELL BIOLOGY (2017)

Review Cell Biology

p53 in survival, death and metabolic health: a lifeguard with a licence to kill

Flore Kruiswijk et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2015)

Review Biochemistry & Molecular Biology

Redox regulation of FoxO transcription factors

Lars-Oliver Klotz et al.

REDOX BIOLOGY (2015)

Article Biochemical Research Methods

NMRFAM-SPARKY: enhanced software for biomolecular NMR spectroscopy

Woonghee Lee et al.

BIOINFORMATICS (2015)

Article Biochemical Research Methods

NMR contributions to structural dynamics studies of intrinsically disordered proteins

Robert Konrat

JOURNAL OF MAGNETIC RESONANCE (2014)

Article Biochemistry & Molecular Biology

The DNA-binding domain mediates both nuclear and cytosolic functions of p53

Ariele Viacava Follis et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2014)

Article Biochemistry & Molecular Biology

The Small GTPase RALA Controls c-Jun N-terminal Kinase-mediated FOXO Activation by Regulation of a JIP1 Scaffold Complex

Maaike C. W. van den Berg et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Chemistry, Multidisciplinary

Structure-Based Design of a Potent Artificial Transactivation Domain Based on p53

Chantal Langlois et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)

Article Multidisciplinary Sciences

Structures of KIX domain of CBP in complex with two FOXO3a transactivation domains reveal promiscuity and plasticity in coactivator recruitment

Feng Wang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Biochemistry & Molecular Biology

Distinct p53 Transcriptional Programs Dictate Acute DNA-Damage Responses and Tumor Suppression

Colleen A. Brady et al.

Article Biochemistry & Molecular Biology

An induced fit mechanism regulates p53 DNA binding kinetics to confer sequence specificity

Tom J. Petty et al.

EMBO JOURNAL (2011)

Article Biochemical Research Methods

Structure of the human FOXO4-DBD-DNA complex at 1.9 A resolution reveals new details of FOXO binding to the DNA

Evzen Boura et al.

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)

Article Cell Biology

Pathways of oncogene-induced senescence in human melanocytic cells

Rajat Bansal et al.

CELL CYCLE (2010)

Review Medicine, General & Internal

MECHANISMS OF DISEASE Alzheimer's Disease

Henry W. Querfurth et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Review Biochemistry & Molecular Biology

Blinded by the Light: The Growing Complexity of p53

Karen H. Vousden et al.

Article Biochemistry & Molecular Biology

Interaction between the Transactivation Domain of p53 and PC4 Exemplifies Acidic Activation Domains as Single-stranded DNA Mimics

Sridharan Rajagopalan et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Biochemistry & Molecular Biology

Biophysical characterizations of human mitochondrial transcription factor A and its binding to tumor suppressor p53

Tuck Seng Wong et al.

NUCLEIC ACIDS RESEARCH (2009)

Article Biochemistry & Molecular Biology

Structural Basis for p300 Taz2-p53 TAD1 Binding and Modulation by Phosphorylation

Hanqiao Feng et al.

STRUCTURE (2009)

Article Biochemistry & Molecular Biology

Biochemical and Structural Characterization of an Intramolecular Interaction in FOXO3a and Its Binding with p53

Feng Wang et al.

JOURNAL OF MOLECULAR BIOLOGY (2008)

Review Oncology

The emerging roles of forkhead box (Fox) proteins in cancer

Stephen S. Myatt et al.

NATURE REVIEWS CANCER (2007)

Article Biochemistry & Molecular Biology

p53 mediates the accelerated onset of senescence of endothelial progenitor cells in diabetes

A Rosso et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Multidisciplinary Sciences

Solution structure of p53 core domain:: Structural basis for its instability

JMP Cañadillas et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Biochemistry & Molecular Biology

Structural details on mdm2-p53 interaction

SW Chi et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Multidisciplinary Sciences

Single-stranded DNA mimicry in the p53 transactivation domain interaction with replication protein A

E Bochkareva et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Review Endocrinology & Metabolism

FoxO proteins in insulin action and metabolism

A Barthel et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2005)

Article Biochemistry & Molecular Biology

Defining the p53 DNA-binding domain BcL-XL-binding interface using NMR

AM Petros et al.

FEBS LETTERS (2004)

Article Multidisciplinary Sciences

Nutrient availability regulates SIRT1 through a forkhead-dependent pathway

S Nemoto et al.

SCIENCE (2004)

Article Biochemistry & Molecular Biology

FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK

MAG Essers et al.

EMBO JOURNAL (2004)

Review Biochemistry & Molecular Biology

FoxOs at the crossroads of cellular metabolism, differentiation, and transformation

D Accili et al.

Article Biochemistry & Molecular Biology

Regulation of cell survival and proliferation by the FOXO (Forkhead box, class 0) subfamily of forkhead transcription factors

KU Birkenkamp et al.

BIOCHEMICAL SOCIETY TRANSACTIONS (2003)

Article Multidisciplinary Sciences

CRINEPT-TROSY NMR reveals p53 core domain bound in an unfolded form to the chaperone Hsp90

S Rüdiger et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Multidisciplinary Sciences

Effects of p21Waf1/Cip1/Sdi1 on cellular gene expression:: Implications for carcinogenesis, senescence, and age-related diseases

BD Chang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)