Total Anterior Staphyloma Secondary to Acanthamoeba Keratitis

There are very few published cases of total anterior staphyloma, all of which have been reported as secondary to fungal keratitis. This study reports the clinical and histopathological findings and subsequent management of a 27-year-old healthy female patient who developed total anterior staphyloma after poor compliance with treatment for clinically diagnosed acanthamoeba keratitis. She underwent a successful evisceration with good long-term results. This case highlights that total anterior staphyloma may also result from untreated keratitis which is not fungal in origin. In cases of fungal and acanthamoeba keratitis, patient compliance with both treatment and follow-up is paramount to avoid vision-threatening sequelae that present significant challenges in their management.

Automated summary

This study reports a case of total anterior staphyloma resulting from untreated acanthamoeba keratitis, highlighting the importance of patient compliance in the management of fungal and acanthamoeba keratitis and in preventing vision-threatening sequelae.