相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Location-specific cell identity rather than exposure to GI microbiota defines many innate immune signalling cascades in the gut epithelium
Ozge Kayisoglu et al.
GUT (2021)
Organs-on-chips: into the next decade
Lucie A. Low et al.
NATURE REVIEWS DRUG DISCOVERY (2021)
Rethinking organoid technology through bioengineering
Elena Garreta et al.
NATURE MATERIALS (2021)
Ephrin receptor A2, the epithelial receptor for Epstein-Barr virus entry, is not available for efficient infection in human gastric organoids
Nina Wallaschek et al.
PLOS PATHOGENS (2021)
Leveling Up Hydrogels: Hybrid Systems in Tissue Engineering
Sara C. Neves et al.
TRENDS IN BIOTECHNOLOGY (2020)
Asymmetric distribution of TLR3 leads to a polarized immune response in human intestinal epithelial cells
Megan L. Stanifer et al.
NATURE MICROBIOLOGY (2020)
Mechanical Stimuli Affect Escherichia coli Heat-Stable Enterotoxin-Cyclic GMP Signaling in a Human Enteroid Intestine-Chip Model
Laxmi Sunuwar et al.
INFECTION AND IMMUNITY (2020)
Mutational signature in colorectal cancer caused by genotoxic pks+E. coli
Cayetano Pleguezuelos-Manzano et al.
NATURE (2020)
An Advanced Human Intestinal Coculture Model Reveals Compartmentalized Host and Pathogen Strategies during Salmonella Infection
Leon N. Schulte et al.
MBIO (2020)
Decellularized tissues as platforms for in vitro modeling of healthy and diseased tissues
Michaela W. McCrary et al.
ACTA BIOMATERIALIA (2020)
A three-dimensional intestinal tissue model reveals factors and small regulatory RNAs important for colonization with Campylobacter jejuni
Mona Alzheimer et al.
PLOS PATHOGENS (2020)
Clostridioides difficile infection damages colonic stem cells via TcdB, impairing epithelial repair and recovery from disease
Steven J. Mileto et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Norovirus Replication in Human Intestinal Epithelial Cells Is Restricted by the Interferon-Induced JAK/STAT Signaling Pathway and RNA Polymerase II-Mediated Transcriptional Responses
Myra Hosmillo et al.
mBio (2020)
The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice
Linlin Bao et al.
NATURE (2020)
TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes
Ruochen Zang et al.
SCIENCE IMMUNOLOGY (2020)
Staphylococcus aureus Lung Infection Results in Down-Regulation of Surfactant Protein-A Mainly Caused by Pro-Inflammatory Macrophages
Elisabeth Schicke et al.
MICROORGANISMS (2020)
Reprogramming of host glutamine metabolism duringChlamydia trachomatisinfection and its key role in peptidoglycan synthesis
Karthika Rajeeve et al.
NATURE MICROBIOLOGY (2020)
Human organoids: model systems for human biology and medicine
Jihoon Kim et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2020)
Homeostatic mini-intestines through scaffold-guided organoid morphogenesis
Mikhail Nikolaev et al.
NATURE (2020)
Engineering transplantable jejunal mucosal grafts using patient-derived organoids from children with intestinal failure
Laween Meran et al.
NATURE MEDICINE (2020)
Genotoxic Effect of Salmonella Paratyphi A Infection on Human Primary Gallbladder Cells
Ludovico P. Sepe et al.
MBIO (2020)
Progenitor identification and SARS-CoV-2 infection in human distal lung organoids
Ameen A. Salahudeen et al.
NATURE (2020)
Organoids in immunological research
Yotam E. Bar-Ephraim et al.
NATURE REVIEWS IMMUNOLOGY (2020)
Polarised epithelial monolayers of the gastric mucosa reveal insights into mucosal homeostasis and defence against infection
Francesco Boccellato et al.
GUT (2019)
Tubuloids derived from human adult kidney and urine for personalized disease modeling
Frans Schutgens et al.
NATURE BIOTECHNOLOGY (2019)
Chronic Chlamydia infection in human organoids increases stemness and promotes age-dependent CpG methylation
Mirjana Kessler et al.
NATURE COMMUNICATIONS (2019)
Controlling Epithelial Polarity: A Human Enteroid Model for Host-Pathogen Interactions
Julia Y. Co et al.
CELL REPORTS (2019)
Increased Programmed Death-Ligand 1 is an Early Epithelial Cell Response to Helicobacter pylori Infection
Loryn Holokai et al.
PLOS PATHOGENS (2019)
Using Human Induced Pluripotent Stem Cell-derived Intestinal Organoids to Study and Modify Epithelial Cell Protection Against Salmonella and Other Pathogens
Emily A. Lees et al.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2019)
A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip
Sasan Jalili-Firoozinezhad et al.
NATURE BIOMEDICAL ENGINEERING (2019)
Disease modelling in human organoids
Madeline A. Lancaster et al.
DISEASE MODELS & MECHANISMS (2019)
Bioengineered Human Organ-on-Chip Reveals Intestinal Microenvironment and Mechanical Forces Impacting Shigella Infection
Alexandre Grassart et al.
CELL HOST & MICROBE (2019)
Studying Cryptosporidium Infection in 3D Tissue-derived Human Organoid Culture Systems by Microinjection
Devanjali Dutta et al.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2019)
A three-dimensional immunocompetent intestine-on-chip model as in vitro platform for functional and microbial interaction studies
Michelle Maurer et al.
BIOMATERIALS (2019)
Shiga toxin sub-type 2a increases the efficiency of Escherichia coli O157 transmission between animals and restricts epithelial regeneration in bovine enteroids
Stephen F. Fitzgerald et al.
PLOS PATHOGENS (2019)
Long-term expanding human airway organoids for disease modeling
Norman Sachs et al.
EMBO JOURNAL (2019)
Modeling Human Digestive Diseases With CRISPR-Cas9-Modified Organoids
Masayuki Fujii et al.
GASTROENTEROLOGY (2019)
Evaluating Shigella flexneri Pathogenesis in the Human Enteroid Model
Sridevi Ranganathan et al.
INFECTION AND IMMUNITY (2019)
An upstream protein-coding region in enteroviruses modulates virus infection in gut epithelial cells
Valeria Lulla et al.
NATURE MICROBIOLOGY (2019)
New Age Strategies To Reconstruct Mucosal Tissue Colonization and Growth in Cell Culture Systems
Alyssa C. Fasciano et al.
MICROBIOLOGY SPECTRUM (2019)
Engineering Organoid Vascularization
Sergei Grebenyuk et al.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2019)
Loss of Paneth Cell Autophagy Causes Acute Susceptibility to Toxoplasma gondii-Mediated Inflammation
Elise Burger et al.
CELL HOST & MICROBE (2018)
Human Serum Albumin Is an Essential Component of the Host Defense Mechanism Against Clostridium difficile Intoxication
Alessandra di Masi et al.
JOURNAL OF INFECTIOUS DISEASES (2018)
Patient-derived organoids model treatment response of metastatic gastrointestinal cancers
Georgios Vlachogiannis et al.
SCIENCE (2018)
A urine-dependent human urothelial organoid offers a potential alternative to rodent models of infection
Harry Horsley et al.
SCIENTIFIC REPORTS (2018)
Bioprinting Perfusion-Enabled Liver Equivalents for Advanced Organ-on-a-Chip Applications
Tobias Grix et al.
GENES (2018)
Modelling Cryptosporidium infection in human small intestinal and lung organoids
Inha Heo et al.
NATURE MICROBIOLOGY (2018)
Modeling Host-Pathogen Interactions in the Context of the Microenvironment: Three-Dimensional Cell Culture Comes of Age
Jennifer Barrila et al.
INFECTION AND IMMUNITY (2018)
Interleukin-22 promotes phagolysosomal fusion to induce protection against Salmonella enterica Typhimurium in human epithelial cells
Jessica L. Forbester et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Evaluating the origin and virulence of a Helicobacter pylori cagA-positive strain isolated from a non-human primate
Kana Hashi et al.
SCIENTIFIC REPORTS (2018)
Apoptosis of intestinal epithelial cells restricts Clostridium difficile infection in a model of pseudomembranous colitis
Pedro H. Saavedra et al.
NATURE COMMUNICATIONS (2018)
Live imaging analysis of human gastric epithelial spheroids reveals spontaneous rupture, rotation and fusion events
T. Andrew Sebrell et al.
CELL AND TISSUE RESEARCH (2018)
A High-Throughput Organoid Microinjection Platform to Study Gastrointestinal Microbiota and Luminal Physiology
Ian A. Williamson et al.
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY (2018)
Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system
Michael J. Workman et al.
NATURE MEDICINE (2017)
Bacterial colonization stimulates a complex physiological response in the immature human intestinal epithelium
David R. Hill et al.
ELIFE (2017)
Type I and Type III Interferons Display Different Dependency on Mitogen-Activated Protein Kinases to Mount an Antiviral State in the Human Gut
Kalliopi Pervolaraki et al.
FRONTIERS IN IMMUNOLOGY (2017)
Intestinal organoids model human responses to infection by commensal and Shiga toxin producing Escherichia coli
Sayali S. Karve et al.
PLOS ONE (2017)
Crosstalk between H9N2 avian influenza virus and crypt-derived intestinal organoids
Lulu Huang et al.
VETERINARY RESEARCH (2017)
A microengineered collagen scaffold for generating a polarized crypt-villus architecture of human small intestinal epithelium
Yuli Wang et al.
BIOMATERIALS (2017)
Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure
Xuyu Qian et al.
CELL (2016)
Zika Virus Depletes Neural Progenitors in Human Cerebral Organoids through Activation of the Innate Immune Receptor TLR3
Jason Dang et al.
CELL STEM CELL (2016)
Modeling infectious diseases and host-microbe interactions in gastrointestinal organoids
Sina Bartfeld
DEVELOPMENTAL BIOLOGY (2016)
Three-dimensional models for studying development and disease: moving on from organisms to organs-on-a-chip and organoids
E. L. Jackson et al.
INTEGRATIVE BIOLOGY (2016)
Frizzled proteins are colonic epithelial receptors for C. difficile toxin B
Liang Tao et al.
NATURE (2016)
Tissue-specific mutation accumulation in human adult stem cells during life
Francis Blokzijl et al.
NATURE (2016)
Pluripotent stem cells in disease modelling and drug discovery
Yishai Avior et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2016)
Replication of human noroviruses in stem cell-derived human enteroids
Khalil Ettayebi et al.
SCIENCE (2016)
Zika virus impairs growth in human neurospheres and brain organoids
Patricia P. Garcez et al.
SCIENCE (2016)
Development of an Advanced Primary Human In Vitro Model of the Small Intestine
Matthias Schweinlin et al.
TISSUE ENGINEERING PART C-METHODS (2016)
A microfluidics-based in vitro model of the gastrointestinal human-microbe interface
Pranjul Shah et al.
NATURE COMMUNICATIONS (2016)
A novel human gastric primary cell culture system for modelling Helicobacter pylori infection in vitro
Philipp Schlaermann et al.
GUT (2016)
Human Clostridium difficile infection: altered mucus production and composition
Melinda A. Engevik et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2015)
Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver
Meritxell Huch et al.
CELL (2015)
Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients
Marc van de Wetering et al.
CELL (2015)
Salmonella Manipulation of Host Signaling Pathways Provokes Cellular Transformation Associated with Gallbladder Carcinoma
Tiziana Scanu et al.
CELL HOST & MICROBE (2015)
In Vitro Expansion of Human Gastric Epithelial Stem Cells and Their Responses to Bacterial Infection
Sina Bartfeld et al.
GASTROENTEROLOGY (2015)
A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents
Ilka Maschmeyer et al.
LAB ON A CHIP (2015)
Organoids as Model for Infectious Diseases: Culture of Human and Murine Stomach Organoids and Microinjection of Helicobacter Pylori
Sina Bartfeld et al.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2015)
Development of an enhanced human gastrointestinal epithelial culture system to facilitate patient-based assays
Kelli L. VanDussen et al.
GUT (2015)
Helicobacter pylori-induced Sonic Hedgehog Expression is Regulated by NFκB Pathway Activation: The Use of a Novel In vitro Model to Study Epithelial Response to Infection
Michael A. Schumacher et al.
HELICOBACTER (2015)
Persistence and Toxin Production by Clostridium difficile within Human Intestinal Organoids Result in Disruption of Epithelial Paracellular Barrier Function
Jhansi L. Leslie et al.
INFECTION AND IMMUNITY (2015)
A biomimetic multicellular model of the airways using primary human cells
Katelyn L. Sellgren et al.
LAB ON A CHIP (2014)
Modelling human development and disease in pluripotent stem-cell-derived gastric organoids
Kyle W. McCracken et al.
NATURE (2014)
Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture
Xingnan Li et al.
NATURE MEDICINE (2014)
Organogenesis in a dish: Modeling development and disease using organoid technologies
Madeline A. Lancaster et al.
SCIENCE (2014)
A functional CFTR assay using primary cystic fibrosis intestinal organoids
Johanna F. Dekkers et al.
NATURE MEDICINE (2013)
Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow
Hyun Jung Kim et al.
LAB ON A CHIP (2012)
The physiological performance of a three-dimensional model that mimics the microenvironment of the small intestine
Jacqueline Pusch et al.
BIOMATERIALS (2011)
Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium
Toshiro Sato et al.
GASTROENTEROLOGY (2011)
Epstein-Barr Virus Infection of Polarized Epithelial Cells via the Basolateral Surface by Memory B Cell-Mediated Transfer Infection
Claire Shannon-Lowe et al.
PLOS PATHOGENS (2011)
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
Toshiro Sato et al.
NATURE (2009)
Self-Organized Formation of Polarized Cortical Tissues from ESCs and Its Active Manipulation by Extrinsic Signals
Mototsugu Eiraku et al.
CELL STEM CELL (2008)