期刊
EUROPEAN POLYMER JOURNAL
卷 160, 期 -, 页码 -出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.eurpolymj.2021.110801
关键词
Bioactive glasses; Osteogenesis; Angiogenesis; Bone tissue engineering; Scaffold; Bone; Biopolymer; Biomaterial; Bio-ceramic; Composite materials
Bioactive glasses have been traditionally used for permeating and repairing bone defects, with 45S5 Bio glass being a prime artificial material developed by Larry Hench. These materials have exceptional biocompatibility and can form a HA coat in the body. Various synthesis techniques have been developed for bioactive glasses containing biocompatible polymers, aiming to review the modern evolution of glass for bone regeneration. These glasses can connect to osseous matter and restore new bone growth over time, ultimately restoring the ailing or defective bone to its original condition and function.
Conventionally, to permeate and repair bone defects, bioactive glasses have been used. Currently, this group of bio-materials has become a rising study for bone tissue engineering applications. 45S5 Bio glass of Larry Hench was the prime artificial material developed to generate a chemical connection with the bone, introducing the domain of bioactive ceramics. Bioactive glass is exceptionally biocompatible and can constitute a HA coat when rooted in the physique. Several characteristics of bioactive glasses, including sterile characteristics, can be nurture by accumulating a variety of biocompatible polymers into the glass. This study aims to review the modern and upgrade evolution of glass for bone regeneration. For bioactive glass containing biocompatible polymers, various synthesized techniques have been developed, including electrospinning, fabrication process, sol-gel process, ultrasonic power, magnetic stirrer, solvent casting technique, and microscopic technique. The materials for bone repair are such as Zein, 58S, Tri-Calcium Phosphate, and Zirconia. Bio-glasses are amorphous silicate-based constituents that connect to osseous matter and can restore newfangled bone progress while dissolving concluded period. As a result, they may restore the ailing or defective bone to its former condition and purpose (osteogenesis).
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