4.6 Article

Absorption, metabolism and excretion of once-weekly somapacitan, a long-acting growth hormone derivative, after single subcutaneous dosing in human subjects

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Absorption, metabolism and excretion of once-weekly somapacitan, a long-acting growth hormone derivative, after single subcutaneous dosing in human subjects

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Summary: Somapacitan is a reversible growth hormone derivative used for the treatment of GH deficiency. In healthy males, the drug is primarily excreted through urine, with metabolites fully degraded and eliminated. The study demonstrates that it is safe and well tolerated.

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