期刊
EUROPEAN JOURNAL OF OPHTHALMOLOGY
卷 32, 期 4, 页码 2234-2240出版社
SAGE PUBLICATIONS LTD
DOI: 10.1177/11206721211054967
关键词
Acute primary angle-closure; bruch's membrane; minimum rim width; optic nerve head; retina nerve fiber layer
This study found that BMO-MRW and RNFLT measurements are significantly reduced 3 months after an APAC, with a strong correlation with intraocular pressure.
Purpose To evaluate Bruch's membrane opening - minimum rim width (BMO-MRW) and peripapillary retinal nerve fiber layer thickness (RNFLT) following an acute primary angle-closure attack (APAC). Materials and methods Nine consecutive patients with unilateral APAC were included. Patients with a bilateral attack, with signs of glaucomatous optic nerve damage or evidence of a previous APAC in either eye were excluded. Three months after the attack, all eyes underwent BMO-MRW and RNFLT measurements with SDOCT. APAC eyes were compared to the contralateral eyes. Results Three months after the attack, mean BMO-MRWs were 281.22 +/- 56.88 mu m and 313.78 +/- 43.48 mu m (P = 0.009) and mean RNFLTs were 78 +/- 15.36 mu m vs 95.78 +/- 10.81 mu m (P = 0.008) in the APAC and contralateral eyes, respectively. RNFLT and BMO-MRW measurements had a strong positive correlation (R = 0.7436, P = 0.013). APAC eyes had a shorter axial length (21.85 +/- 1.21 vs 22 +/- 1.07, P = 0.042) and shallower anterior chamber depth (2.29 +/- 0.21 vs 2.41 +/- 0.12, P = 0.039) than contralateral eyes. IOP at presentation showed a strong negative correlation with both BMO-MRW (R = -0.7669, P = 0.009) and RNFLT measurements (R = -0.7723, P = 0.008). Conclusion BMO-MRW and RNFLT measurements are significantly reduced 3 months after an APAC when compared to the contralateral eye. IOP at presentation may have an impact on the reduction of these parameters.
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