期刊
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
卷 49, 期 2, 页码 445-459出版社
SPRINGER
DOI: 10.1007/s00259-021-05536-4
关键词
PET; CT; MRI; Total-body; Sensitivity; Long axial FOV
资金
- Projekt DEAL
This study summarizes the current status and future developments of total-body PET/CT scanners, with three human TB PET/CT systems developed and increasing system sensitivity paving the way for new imaging methods.
Purpose Since the 1990s, PET has been successfully combined with MR or CT systems. In the past years, especially PET systems have seen a trend towards an enlarged axial field of view (FOV), up to a factor of ten. Methods Conducting a thorough literature research, we summarize the status quo of contemporary total-body (TB) PET/CT scanners and give an outlook on possible future developments. Results Currently, three human TB PET/CT systems have been developed: The PennPET Explorer, the uExplorer, and the Biograph Vision Quadra realize aFOVs between 1 and 2 m and show a tremendous increase in system sensitivity related to their longer gantries. Conclusion The increased system sensitivity paves the way for short-term, low-dose, and dynamic TB imaging as well as new examination methods in almost all areas of imaging.
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