相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。In search of definitions: Cancer-associated fibroblasts and their markers
Martin Nurmik et al.
INTERNATIONAL JOURNAL OF CANCER (2020)
Discovery of isopenicin A, a meroterpenoid as a novel inhibitor of tubulin polymerization
Lin Chen et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2020)
Hydrogen sulfide releasing oridonin derivatives induce apoptosis through extrinsic and intrinsic pathways
Haonan Li et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020)
Structure-activity relationships (SAR) of triazine derivatives: Promising antimicrobial agents
Hao Liu et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020)
Therapeutic potentials of curcumin in the treatment of glioblstoma
Zahra Shabaninejad et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020)
Synthesis and anticancer activity of new tetrahydroquinoline hybrid derivatives tethered to isoxazoline moiety
Cristian C. Bernal et al.
MEDICINAL CHEMISTRY RESEARCH (2020)
Antimicrobial, Antioxidant, and Anticancer Activities of Some Novel Isoxazole Ring Containing Chalcone and Dihydropyrazole Derivatives
Afzal Shaik et al.
MOLECULES (2020)
Application of curcumin and its derivatives in tumor multidrug resistance
Ting Xu et al.
PHYTOTHERAPY RESEARCH (2020)
Synthesis of novel isoxazole functionalized pyrazolo[3,4-b]pyridine derivatives; their anticancer activity
Sampath Ravula et al.
JOURNAL OF HETEROCYCLIC CHEMISTRY (2020)
In silico docking studies and synthesis of new phosphoramidate derivatives of 6-fluoro-3-(piperidin-4-yl)benzo[d]isoxazole as potential antimicrobial agents
Munichandra Reddy Sivala et al.
JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION (2020)
Knowledge of symptoms and risk factors of breast cancer among women: a community based study in a low socio-economic area of Mumbai, India
Ranjan Kumar Prusty et al.
BMC WOMENS HEALTH (2020)
New series of isoxazole derivatives targeting EGFR-TK: Synthesis, molecular modeling and antitumor evaluation
Eman T. Warda et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2020)
Design, synthesis and biological evaluation of isoxazole-naphthalene derivatives as anti-tubulin agents
Guangcheng Wang et al.
ARABIAN JOURNAL OF CHEMISTRY (2020)
Antiproliferative benzothiazoles incorporating a trimethoxyphenyl scaffold as novel colchicine site tubulin polymerisation inhibitors
Dong-Jun Fu et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2020)
Colchicine-Binding Site Inhibitors from Chemistry to Clinic: A Review
Eavan C. McLoughlin et al.
PHARMACEUTICALS (2020)
Recent Development in Indole Derivatives as Anticancer Agents for Breast Cancer
Kamalprect Kaur et al.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2019)
Anticancer and DNA binding studies of potential amino acids based quinazolinone analogs: Synthesis, SAR and molecular docking
K. P. Rakesh et al.
BIOORGANIC CHEMISTRY (2019)
Innovative nano-carriers in anticancer drug delivery-a comprehensive review
Peng Dong et al.
BIOORGANIC CHEMISTRY (2019)
The significance of N-methylpicolinamides in the development of anticancer therapeutics: Synthesis and structure-activity relationship (SAR) studies
Balakrishna Moku et al.
BIOORGANIC CHEMISTRY (2019)
ER alpha selective chromone, isoxazolylchromones, induces ROS-mediated cell death without autophagy
Swati Kaushik et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2019)
An Intramolecular Wittig Approach toward Heteroarenes: Synthesis of Pyrazoles, Isoxazoles, and Chromenone-oximes
Pankaj V. Khairnar et al.
ORGANIC LETTERS (2019)
Synthesis of β-Isoxazole Carbonyl Derivatives and Their Analogues via Palladium-Catalyzed Sequential C(sp2)-O/C(sp2)-C(sp3) Bond Formations
Wanqing Wu et al.
ADVANCED SYNTHESIS & CATALYSIS (2019)
Synthetic approaches and pharmaceutical applications of chloro-containing molecules for drug discovery: A critical review
Wan-Yin Fang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
Synthesis of Furoxans and Isoxazoles via Divergent [2+1+1+1] Annulations of Sulfoxonium Ylides and tBuONO
Zhonghe Tang et al.
ORGANIC LETTERS (2019)
Iterative Assembly of Nitrile Oxides and Ynamides: Synthesis of Isoxazoles and Pyrroles
Changwei Chen et al.
JOURNAL OF ORGANIC CHEMISTRY (2019)
Four-Component Reactions for the Synthesis of Perfluoroalkyl Isoxazoles
Yuanjin Chen et al.
ACS CATALYSIS (2019)
Triazole derivatives as inhibitors of Alzheimer's disease: Current developments and structure-activity relationships
Man Xu et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
Harnessing the TEMPO-Catalyzed Aerobic Oxidation for Machetti-De Sarlo Reaction toward Sustainable Synthesis of Isoxazole Libraries
Murugan Vadivelu et al.
JOURNAL OF ORGANIC CHEMISTRY (2019)
Regioselective Synthesis of Functionalized 3-or 5-Fluoroalkyl Isoxazoles and Pyrazoles from Fluoroalkyl Ynones and Binucleophiles
Bohdan A. Chalyk et al.
JOURNAL OF ORGANIC CHEMISTRY (2019)
Synthesis of 5-(Fluoroalkyl)isoxazole Building Blocks by Regioselective Reactions of Functionalized Halogenoximes
Bohdan A. Chalyk et al.
JOURNAL OF ORGANIC CHEMISTRY (2019)
Copper-Catalyzed Cascade Cyclization Reactions of Diazo Compounds with tert-Butyl Nitrite and Alkynes: One-Pot Synthesis of Isoxazoles
Xue-Di Wang et al.
JOURNAL OF ORGANIC CHEMISTRY (2019)
Are aromatase inhibitors associated with higher myocardial infarction risk in breast cancer patients? A Medicare population-based study
Sailaja Kamaraju et al.
CLINICAL CARDIOLOGY (2019)
Pharmaceutical and medicinal significance of sulfur (SVI)-Containing motifs for drug discovery: A critical review
Chuang Zhao et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
Synthesis, biological evaluation, molecular docking and DFT calculations of novel benzenesulfonamide derivatives
Asmaa M. Fahim et al.
JOURNAL OF MOLECULAR STRUCTURE (2019)
Continuous Flow Synthesis of Isoxazoles via Vinyl Azides from Friedel-Crafts Acylation of Alkynes: A Modulated Troubleshooting Optimization Approach
Hyungmo Koo et al.
ORGANIC LETTERS (2019)
Iron-Mediated Synthesis of Isoxazoles from Alkynes: Using Iron(III) Nitrate as a Nitration and Cyclization Reagent
Zhenzhen Lai et al.
JOURNAL OF ORGANIC CHEMISTRY (2018)
Podophyllotoxin derivatives as an excellent anticancer aspirant for future chemotherapy: A key current imminent needs
Xu Zhang et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2018)
Synthesis, biological evaluation and molecular docking studies of aminochalcone derivatives as potential anticancer agents by targeting tubulin colchicine binding site
Guangcheng Wang et al.
BIOORGANIC CHEMISTRY (2018)
Recent advance in oxazole-based medicinal chemistry
Hui-Zhen Zhang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)
Apoptosis: A Target for Anticancer Therapy
Claire M. Pfeffer et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Synthesis and Preliminarily Cytotoxicity to A549, HCT116 and MCF-7 Cell Lines of Thieno[2,3-d]pyrimidine Derivatives containing Isoxazole Moiety
Jianping Yong et al.
LETTERS IN DRUG DESIGN & DISCOVERY (2018)
The synthetic and therapeutic expedition of isoxazole and its analogs
Neetu Agrawal et al.
MEDICINAL CHEMISTRY RESEARCH (2018)
Cu-Catalyzed Synthesis of Fluoroalkylated Isoxazoles from Commercially Available Amines and Alkynes
Xiao-Wei Zhang et al.
ORGANIC LETTERS (2018)
Discrete Fourier Transform-Based Multivariate Image Analysis: Application to Modeling of Aromatase Inhibitory Activity
Stephen J. Barigye et al.
ACS COMBINATORIAL SCIENCE (2018)
Synthesis and cellular bioactivities of novel isoxazole derivatives incorporating an arylpiperazine moiety as anticancer agents
Burcu Caliskan et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2018)
Catalyst- and solvent-free mechanochemical synthesis of isoxazoles from N-hydroxybenzimidoyl chlorides and enamino carbonyl compounds
Hui Xu et al.
TETRAHEDRON (2018)
Oxidative Cyclization of β-Aminoacrylamides Mediated by PhIO: Chemoselective Synthesis of Isoxazoles and 2H-Azirines
Chaoran Li et al.
JOURNAL OF ORGANIC CHEMISTRY (2018)
Regioselective synthesis of isoxazole and 1,2,4-oxadiazole-derived phosphonates via [3+2] cycloaddition
Bohdan A. Chalyk et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2018)
Design, synthesis and pharmacological evaluation of 4,5-diarylisoxazols bearing amino acid residues within the 3-amido motif as potent heat shock protein 90 (Hsp90) inhibitors
Chi Zhang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
Design, synthesis, and biological evaluation of cyclic-indole derivatives as anti-tumor agents via the inhibition of tubulin polymerization
Jun Yan et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
Isoxazole ring as a useful scaffold in a search for new therapeutic agents
Angelika Sysak et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
tert-Butyl Nitrite-Mediated Domino Synthesis of Isoxazolines and Isoxazoles from Terminal Aryl Alkenes and Alkynes
Prasenjit Sau et al.
JOURNAL OF ORGANIC CHEMISTRY (2017)
The synthetic antihyperlipidemic drug potassium piperate selectively kills breast cancer cells through inhibiting G1-S-phase transition and inducing apoptosis
Lifei Fan et al.
ONCOTARGET (2017)
Azomethines, isoxazole, N-substituted pyrazoles and pyrimidine containing curcumin derivatives: Urease inhibition and molecular modeling studies
Mahmood Ahmed et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)
Synthesis and biological characterization of 3-(imidazol-1-ylmethyl) piperidine sulfonamides as aromatase inhibitors
Mauro Di Matteo et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2016)
Synthesis, biological evaluation, and molecular docking studies of new pyrazol-3-one derivatives with aromatase inhibition activities
Xue-Jing Yi et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2016)
Phospholipase A(2) Isoforms as Novel Targets for Prevention and Treatment of Inflammatory and Oncologic Diseases
Nagendra Sastry Yarla et al.
CURRENT DRUG TARGETS (2016)
Synthesis of new secretory phospholipase A2-inhibitory indole containing isoxazole derivatives as anti-inflammatory and anticancer agents
Srinivasa Rao Pedada et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2016)
Recent developments of C-4 substituted coumarin derivatives as anticancer agents
Jyoti Dandriyal et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2016)
Rociletinib, a third generation EGFR tyrosine kinase inhibitor: current data and future directions
Jody C. Chuang et al.
EXPERT OPINION ON PHARMACOTHERAPY (2016)
Design, Synthesis and Biological Evaluation of Stilbene Derivatives as Novel Inhibitors of Protein Tyrosine Phosphatase 1B
Haibing He et al.
MOLECULES (2016)
Synthesis of indole-quinoline-oxadiazoles: their anticancer potential and computational tubulin binding studies
Pooja R. Kamath et al.
RESEARCH ON CHEMICAL INTERMEDIATES (2016)
Nuclear and extranuclear-initiated estrogen receptor signaling crosstalk and endocrine resistance in breast cancer
Eylem Kulkoyluoglu et al.
STEROIDS (2016)
Hypervalent iodine mediated synthesis of di- and tri-substituted isoxazoles via [3+2] cycloaddition of nitrile oxides
Ankur Singhal et al.
TETRAHEDRON LETTERS (2016)
A Rational Approach for the Identification of Non-Hydroxamate HDAC6-Selective Inhibitors
Laura Goracci et al.
SCIENTIFIC REPORTS (2016)
Recent Developments in the Synthesis and Reactivity of Isoxazoles: Metal Catalysis and Beyond
Feng Hu et al.
ADVANCED SYNTHESIS & CATALYSIS (2015)
New indole-isoxazolone derivatives: Synthesis, characterisation and in vitro SIRT1 inhibition studies
Naveen Panathur et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2015)
Mitochondrial apoptosis: killing cancer using the enemy within
J. Lopez et al.
BRITISH JOURNAL OF CANCER (2015)
Design, Synthesis and Molecular Docking Studies of Novel Indole-Pyrimidine Hybrids as Tubulin Polymerization Inhibitors
Meng-Jin Hu et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2015)
Discovery of 4-arylamido 3-methyl isoxazole derivatives as novel FMS kinase inhibitors
Daseul Im et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2015)
Cell Death Signaling
Douglas R. Green et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2015)
Synthesis of 3,5-Disubstituted Isoxazoles and Isoxazolines in Deep Eutectic Solvents
Juana M. Perez et al.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING (2015)
Recent developments in tubulin polymerization inhibitors: An overview
Ramandeep Kaur et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2014)
A novel anthracene derivative, MHY412, induces apoptosis in doxorubicin-resistant MCF-7/Adr human breast cancer cells through cell cycle arrest and downregulation of P-glycoprotein expression
Umasankar De et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2014)
Development of Pyrazolone and Isoxazol-5-one Cambinol Analogues as Sirtuin Inhibitors
Sumit S. Mahajan et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Targeting the apoptosis pathway in hematologic malignancies
Shadia Zaman et al.
LEUKEMIA & LYMPHOMA (2014)
Apoptosis and Molecular Targeting Therapy in Cancer
Mohamed Hassan et al.
BIOMED RESEARCH INTERNATIONAL (2014)
Contraindicated Use of Bevacizumab and Toxicity in Elderly Patients With Cancer
Dawn L. Hershman et al.
JOURNAL OF CLINICAL ONCOLOGY (2013)
Whole-genome analysis informs breast cancer response to aromatase inhibition
Matthew J. Ellis et al.
NATURE (2012)
Pertuzumab plus Trastuzumab plus Docetaxel for Metastatic Breast Cancer
Jose Baselga et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
An Overview of Tubulin Inhibitors That Interact with the Colchicine Binding Site
Yan Lu et al.
PHARMACEUTICAL RESEARCH (2012)
Breast cancer statistics, 2011
Carol DeSantis et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2011)
Exemestane for Breast-Cancer Prevention in Postmenopausal Women
Paul E. Goss et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Potential utility of natural products as regulators of breast cancer-associated aromatase promoters
Shabana I. Khan et al.
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY (2011)
Design and synthesis of novel isoxazole-based HDAC inhibitors
Paola Conti et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2010)
Antifolate Inhibitors of Thymidylate Synthase as Anticancer Drugs
A. Jarmula
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2010)
Site-Specific Phosphorylation Induces Functionally Active Conformation in the Intrinsically Disordered N-Terminal Activation Function (AF1) Domain of the Glucocorticoid Receptor
Anna M. S. Garza et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009
G. Kroemer et al.
CELL DEATH AND DIFFERENTIATION (2009)
Rational Combinations Using HDAC Inhibitors
Michael Bots et al.
CLINICAL CANCER RESEARCH (2009)
Effect of Raloxifene on Stroke and Venous Thromboembolism According to Subgroups in Postmenopausal Women at Increased Risk of Coronary Heart Disease
Lori Mosca et al.
STROKE (2009)
Antitumor effects of curcumin and structurally β-diketone modified analogs on multidrug resistant cancer cells
Daniele Simoni et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
BH3-only proteins in apoptosis and beyond: an overview
E. Lomonosova et al.
ONCOGENE (2008)
Curcumin inhibits tumor growth and angiogenesis in ovarian carcinoma by targeting the nuclear factor-κB pathway
Yvonne G. Lin et al.
CLINICAL CANCER RESEARCH (2007)
Protein tyrosine phosphatases: from genes, to function, to disease
Nicholas K. Tonks
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)
Phospholipase A(2) inhibitors as potential anti-inflammatory agents
MC Meyer et al.
CURRENT PHARMACEUTICAL DESIGN (2005)
Protein tyrosine phosphatases in the human genome
A Alonso et al.
CELL (2004)
5-Fluorouracil: Mechanisms of action and clinical strategies
DB Longley et al.
NATURE REVIEWS CANCER (2003)
Cell signaling by receptor tyrosine kinases
J Schlessinger
CELL (2000)