4.7 Article

P2Y12 antagonists: Approved drugs, potential naturally isolated and synthesised compounds, and related in-silico studies

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Cardiac & Cardiovascular Systems

Salvianolic acid a inhibits platelet activation and aggregation in patients with type 2 diabetes mellitus

Ai-ming Zhou et al.

BMC CARDIOVASCULAR DISORDERS (2020)

Review Biochemistry & Molecular Biology

P2Y12 Inhibition beyond Thrombosis: Effects on Inflammation

Alexandre Mansour et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Cardiac & Cardiovascular Systems

Novel Antiplatelet Agents in Cardiovascular Disease

Maximilian Tscharre et al.

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS (2020)

Review Biochemistry & Molecular Biology

Advances in Saponin Diversity ofPanax ginseng

Xiangmin Piao et al.

MOLECULES (2020)

Review Agriculture, Multidisciplinary

Health Benefits of Silybum marianum: Phytochemistry, Pharmacology, and Applications

Xin Wang et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2020)

Review Chemistry, Medicinal

Marine Antithrombotics

Rohini Dwivedi et al.

MARINE DRUGS (2020)

Review Neurosciences

Pharmacology of P2Y receptors

Ivar von Kugelgen

BRAIN RESEARCH BULLETIN (2019)

Article Biochemistry & Molecular Biology

Chemical constituents from the leaves of Crataegus pinnatifida Bge

Wanchun Chu et al.

BIOCHEMICAL SYSTEMATICS AND ECOLOGY (2019)

Article Pharmacology & Pharmacy

Isorhapontigenin, a resveratrol analogue selectively inhibits ADP-stimulated platelet activation

Divyashree Ravishankar et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2019)

Article Biochemistry & Molecular Biology

Antithrombotic Effects of Paeoniflorin from Paeonia suffruticosa by Selective Inhibition on Shear Stress-Induced Platelet Aggregation

Thien Ngo et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Nutrition & Dietetics

Dual Anticoagulant/Antiplatelet Activity of Polyphenolic Grape Seeds Extract

Michal Bijak et al.

NUTRIENTS (2019)

Review Chemistry, Multidisciplinary

Salvia miltiorrhiza Burge (Danshen): a golden herbal medicine in cardiovascular therapeutics

Zhuo-ming Li et al.

ACTA PHARMACOLOGICA SINICA (2018)

Article Chemistry, Medicinal

Reversible, orally available ADP receptor (P2Y12) antagonists Part I: Hit to lead process

Imadul Islam et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2018)

Article Biochemistry & Molecular Biology

Flavonolignans reduce the response of blood platelet to collagen

Michal Bijak et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)

Review Biochemistry & Molecular Biology

Amino Acids in the Development of Prodrugs

Nuno Vale et al.

MOLECULES (2018)

Article Multidisciplinary Sciences

Molecular Docking of Ferulic Acid Derivatives on P2Y12 Receptor and their ADMET Prediction

Juni Ekowati et al.

JOURNAL OF MATHEMATICAL AND FUNDAMENTAL SCIENCES (2018)

Article Biochemistry & Molecular Biology

Investigating the binding mechanism of novel 6-aminonicotinate-based antagonists with P2Y12 by 3D-QSAR, docking and molecular dynamics simulations

Shengfu Zhou et al.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2017)

Article Biochemistry & Molecular Biology

Flavonolignans inhibit ADP induced blood platelets activation and aggregation in whole blood

Michal Bijak et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2017)

Review Biochemistry & Molecular Biology

Natural Antioxidants in Foods and Medicinal Plants: Extraction, Assessment and Resources

Dong-Ping Xu et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Article Plant Sciences

The inhibitory activity of ginsenoside Rp4 in adenosine diphosphate-induced platelet aggregation

Young-Min Son et al.

JOURNAL OF GINSENG RESEARCH (2017)

Article Multidisciplinary Sciences

Light transmission aggregometry using pre-coated microtiter plates and a Victor X5 plate reader

Pernille Just Vinholt et al.

PLOS ONE (2017)

Article Chemistry, Medicinal

New highly active antiplatelet agents with dual specificity for platelet P2Y(1) and P2Y(12) adenosine diphosphate receptors

Ivan B. Yanachkov et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2016)

Article Chemistry, Medicinal

Features of reversible P2Y12 receptor antagonists based on piperazinyl-glutamate-pyridines

Zhen Zhang et al.

MEDICINAL CHEMISTRY RESEARCH (2016)

Letter Biochemistry & Molecular Biology

Analysis of the Genome Sequence of the Medicinal Plant Salvia miltiorrhiza

Haibin Xu et al.

MOLECULAR PLANT (2016)

Article Biochemistry & Molecular Biology

Identification of a New Morpholine Scaffold as a P2Y12 Receptor Antagonist

Young Ha Ahn et al.

MOLECULES (2016)

Review Biochemistry & Molecular Biology

Open challenges in structure-based virtual screening: Receptor modeling, target flexibility consideration and active site water molecules description

Francesca Spyrakis et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2015)

Article Hematology

G-Protein-Coupled Receptors Signaling Pathways in New Antiplatelet Drug Development

Paul A. Gurbel et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2015)

Review Biochemistry & Molecular Biology

Enhanced sampling techniques in molecular dynamics simulations of biological systems

Rafael C. Bernardi et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2015)

Article Biochemistry & Molecular Biology

Modeling ligand recognition at the P2Y12 receptor in light of X-ray structural information

Silvia Paoletta et al.

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2015)

Review Hematology

P2Y12 receptors: structure and function

M. Cattaneo

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2015)

Editorial Material Biotechnology & Applied Microbiology

Anticancer Properties of Natural Products

Istvan Zupko et al.

BIOMED RESEARCH INTERNATIONAL (2015)

Review Biochemistry & Molecular Biology

Purinergic control of inflammation and thrombosis: Role of P2X1 receptors

Cecile Oury et al.

COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2015)

Review Biochemical Research Methods

Recent advances in natural product discovery

Yunzi Luo et al.

CURRENT OPINION IN BIOTECHNOLOGY (2014)

Review Biochemistry & Molecular Biology

P2X and P2Y Receptors-Role in the Pathophysiology of the Nervous System

Kamila Puchalowicz et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2014)

Article Biochemistry & Molecular Biology

Chemical Constituents from Licania cruegeriana and Their Cardiovascular and Antiplatelet Effects

Omar Estrada et al.

MOLECULES (2014)

Article Multidisciplinary Sciences

Agonist-bound structure of the human P2Y12 receptor

Jin Zhang et al.

NATURE (2014)

Article Multidisciplinary Sciences

Structure of the human P2Y12 receptor in complex with an antithrombotic drug

Kaihua Zhang et al.

NATURE (2014)

Article Hematology

Ginsenoside Rg1 inhibits platelet activation and arterial thrombosis

Qi Zhou et al.

THROMBOSIS RESEARCH (2014)

Review Cardiac & Cardiovascular Systems

Historical Lessons in Translational Medicine Cyclooxygenase Inhibition and P2Y12 Antagonism

Desmond J. Fitzgerald et al.

CIRCULATION RESEARCH (2013)

Review Chemistry, Medicinal

Recent advances in natural products from plants for treatment of liver diseases

Aihua Zhang et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2013)

Article Chemistry, Multidisciplinary

An overview of the Amber biomolecular simulation package

Romelia Salomon-Ferrer et al.

WILEY INTERDISCIPLINARY REVIEWS-COMPUTATIONAL MOLECULAR SCIENCE (2013)

Article Endocrinology & Metabolism

Platelet Granule Exocytosis: A Comparison with Chromaffin Cells

Jennifer L. Fitch-Tewfik et al.

Frontiers in Endocrinology (2013)

Article Cardiac & Cardiovascular Systems

Platelet hyperaggregability in high-fat fed rats: A role for intraplatelet reactive-oxygen species production

Priscila F. Monteiro et al.

CARDIOVASCULAR DIABETOLOGY (2012)

Article Biochemistry & Molecular Biology

Surflex-Dock: Docking benchmarks and real-world application

Russell Spitzer et al.

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2012)

Article Chemistry, Medicinal

A novel series of piperazinyl-pyridine ureas as antagonists of the purinergic P2Y12 receptor

Peter Bach et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2011)

Review Pharmacology & Pharmacy

Molecular Recognition in the Case of Flexible Targets

Anthony Ivetac et al.

CURRENT PHARMACEUTICAL DESIGN (2011)

Review Pharmacology & Pharmacy

State-of-the-art in ligand-based virtual screening

Peter Ripphausen et al.

DRUG DISCOVERY TODAY (2011)

Article Biochemistry & Molecular Biology

Comparison of three GPCR structural templates for modeling of the P2Y12 nucleotide receptor

Francesca Deflorian et al.

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2011)

Article Cell Biology

P2Y12 receptor in platelet activation

Soochong Kim et al.

PLATELETS (2011)

Article Chemistry, Medicinal

Part II: Piperazinyl-glutamate-pyridines as potent orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation

John J. Parlow et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)

Editorial Material Cardiac & Cardiovascular Systems

New P2Y12 Inhibitors

Marco Cattaneo

CIRCULATION (2010)

Article Plant Sciences

Topsentinols, 24-Isopropyl Steroids from the Marine Sponge Topsentia sp.

Jingqiu Dai et al.

JOURNAL OF NATURAL PRODUCTS (2010)

Article Pharmacology & Pharmacy

TICAGRELOR

S. L. Davies

DRUGS OF TODAY (2010)

Article Chemistry, Medicinal

Piperazinyl-glutamate-pyrimidines as potent P2Y12 antagonists for inhibition of platelet aggregation

John J. Parlow et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)

Article Chemistry, Multidisciplinary

AutoDock4 and AutoDockTools4: Automated Docking with Selective Receptor Flexibility

Garrett M. Morris et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2009)

Article Hematology

P2Y12 antagonism -: Promises and challenges

Alan D. Michelson

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2008)

Article Pharmacology & Pharmacy

In vitro plasma stability, permeability and solubility of mercaptoacetamide histone deacetylase inhibitors

Roula Konsoula et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2008)

Article Hematology

Dual antiplatelet therapy unmasks distinct platelet reactivity in patients with coronary artery disease

A. J. Peace et al.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2008)

Article Biotechnology & Applied Microbiology

Antioxidant activities of phlorotannins isolated from Japanese Laminariaceae

Toshiyuki Shibata et al.

JOURNAL OF APPLIED PHYCOLOGY (2008)

Article Medical Laboratory Technology

Novel molecular defect in the platelet ADP receptor P2Y(12) of a patient with haemorrhagic diathesis

Jasper A. Remijn et al.

CLINICAL CHEMISTRY AND LABORATORY MEDICINE (2007)

Article Chemistry, Medicinal

Extra precision glide: Docking and scoring incorporating a model of hydrophobic enclosure for protein-ligand complexes

Richard A. Friesner et al.

JOURNAL OF MEDICINAL CHEMISTRY (2006)

Article Chemistry, Medicinal

MolDock: A new technique for high-accuracy molecular docking

Rene Thomsen et al.

JOURNAL OF MEDICINAL CHEMISTRY (2006)

Review Pharmacology & Pharmacy

Biology and pharmacology of the platelet P2Y(12) receptor

Robert F. Storey

CURRENT PHARMACEUTICAL DESIGN (2006)

Article Plant Sciences

Stilbene derivatives from Gnetum cleistostachyum

CS Yao et al.

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2005)

Article Chemistry, Medicinal

A new sterol sulfate, Sch 572423, from a marine sponge, Topsentia sp.

SW Yang et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2003)

Article Food Science & Technology

Inhibitory activity of brown algal phlorotannins against hyaluronidase

T Shibata et al.

INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY (2002)