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Review
Critical Care Medicine
Ranju T. Dhawan et al.
Summary: COVID-19 is associated with pulmonary thrombosis and thromboembolism, potentially leading to pulmonary fibrotic damage and long-term consequences. A proactive follow-up strategy is needed to evaluate residual clot burden, small vessel injury, and potential hemodynamic sequelae. A nuanced and physiological approach to follow-up imaging is crucial for informing therapeutic strategies in case of clinically significant pulmonary vascular sequelae.
LANCET RESPIRATORY MEDICINE
(2021)
Article
Biochemistry & Molecular Biology
Carole H. Sudre et al.
Summary: Reports on long-lasting COVID-19 symptoms, known as 'long COVID', are increasing. Analysis of data from over 4,000 COVID-19 cases revealed that long COVID is more common in older individuals, those with higher body mass index, and females. Experiencing more than five symptoms in the first week of illness was associated with long COVID. A simple model showed promise in distinguishing between short and long COVID cases early in the disease.
Article
Multidisciplinary Sciences
Ziyad Al-Aly et al.
Summary: This study comprehensively describes the post-acute sequelae of COVID-19 using national healthcare databases, finding increased risk of death and use of health resources beyond the first 30 days of illness, as well as incident sequelae in various organ systems, increased use of therapeutic agents, and evidence of laboratory abnormalities. The findings show a risk gradient according to the severity of acute COVID-19 infection and highlight the burden of health loss experienced by patients who survive the acute phase.
Review
Biochemistry & Molecular Biology
Ani Nalbandian et al.
Summary: SARS-CoV-2 is responsible for the COVID-19 pandemic, causing global healthcare crises. Recovery from COVID-19 may lead to persistent symptoms and long-term complications, prompting the need for multidisciplinary care and follow-up for survivors.
Editorial Material
Endocrinology & Metabolism
Kamlesh Khunti et al.
Summary: Cardiometabolic conditions, like type 1 and type 2 diabetes mellitus, are linked to severe COVID-19 and long COVID. Interventions targeting multiple risk factors, along with the use of novel glucose-lowering agents, are recommended for managing long COVID in people.
NATURE REVIEWS ENDOCRINOLOGY
(2021)
Article
Multidisciplinary Sciences
Liguo Zhang et al.
Summary: Researchers have found that SARS-CoV-2 RNA may be reverse-transcribed and integrated into the DNA of human cells, leading to positive PCR results in patients even after infection and recovery. However, the integrated viral sequences mainly consist of subgenomic sequences, which cannot produce infectious virus.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Editorial Material
Public, Environmental & Occupational Health
Alex Burdorf et al.
SCANDINAVIAN JOURNAL OF WORK ENVIRONMENT & HEALTH
(2021)
Review
Virology
Bruno Silva Andrade et al.
Summary: The global COVID-19 pandemic has led to millions of infections, creating a long-term care burden for survivors. It is crucial to study both short-term and long-term effects, as they impact various human systems.
Article
Cardiac & Cardiovascular Systems
George Joy et al.
Summary: This study found that there was no significant difference in the occurrence of cardiovascular abnormalities between seropositive and seronegative healthy healthcare workers 6 months after mild COVID-19 infection.
JACC-CARDIOVASCULAR IMAGING
(2021)
Editorial Material
Pediatrics
Ellinor Sterky et al.
Article
Medicine, General & Internal
Shiun Woei Wong et al.
Summary: This study described 3 cases of ST-segment elevation myocardial infarction in healthy male patients who recovered from COVID-19, showing features of hypercoagulability and treated with dual antiplatelet therapy, angiotensin-converting-enzyme inhibitor, beta blocker, and statin. The cases highlight the strong thrombogenic nature of COVID-19 that persisted among recovered patients and emphasize the need for further research on long COVID to identify endotheliopathy and thrombotic sequalae.
ANNALS ACADEMY OF MEDICINE SINGAPORE
(2021)
Article
Nilesh R. Ghugre et al.
Journal of Cardiology Cases
(2021)
News Item
Medicine, General & Internal
Adrian O'Dowc
Summary: A study found that persistent symptoms of Covid-19 are associated with factors such as age, gender, weight, smoking habits, living environment, and hospitalization history. Fatigue, shortness of breath, muscle aches, and difficulty sleeping are the most common persistent symptoms.
BMJ-BRITISH MEDICAL JOURNAL
(2021)
Article
Medicine, General & Internal
Modesto M. Maestre-Muniz et al.
Summary: The study investigated post-acute health consequences and mortality one year after hospital discharge among survivors of acute COVID-19. The findings revealed a 7.5% mortality rate among survivors and a significant proportion experiencing ongoing symptoms 1 year after disease onset.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Dimitrios Richter et al.
Summary: Cardiovascular involvement in COVID-19 is a key factor in determining prognosis during the acute phase of the disease. Potential chronic implications of the late phase and appropriate approaches to these patients remain unclear. Managing post-COVID patients with cardiovascular complications and integrating new information on COVID-19 are new challenges for cardiologists.
Review
Medicine, Research & Experimental
Clement C. E. Lee et al.
Summary: COVID-19 has been reported to cause cardiovascular complications such as myocardial injury, thromboembolic events, arrhythmia, and heart failure through multiple mechanisms, potentially related to direct viral invasion of cardiomyocytes or inflammation.
Review
Medicine, General & Internal
Eleonora Di Salvo et al.
Summary: The role of alarmins in patients affected by COVID-19 disease and their relationship with commonly reported comorbidities are the focus of current research. There is limited literature on this specific topic, but preliminary evidence confirms the involvement of danger signals in amplifying the inflammatory reaction associated with SARS-CoV-2 infection.
ANNALS OF MEDICINE
(2021)
Letter
Cardiac & Cardiovascular Systems
Bingwen Eugene Fan et al.
JOURNAL OF THROMBOSIS AND THROMBOLYSIS
(2021)
Letter
Medicine, General & Internal
Angelo Carfi et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2020)
Editorial Material
Medicine, General & Internal
Trisha Greenhalgh et al.
BMJ-BRITISH MEDICAL JOURNAL
(2020)
