期刊
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
卷 29, 期 10, 页码 14903-14913出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s11356-021-16865-0
关键词
PM2 5; Lung function; Rural areas; Long term; Risk factors; China
资金
- National Key Research and Development Project Ningxia Cohort from China Northwest Cohort [2017YFC0907204]
- Ningxia Medical University scientific research project, Top Discipline of Public Health and Prevent Medicine, Education Department of Ningxia, China [NXYLXK2017B08]
The study aimed to identify the factors affecting lung function and the correlation between PM2.5 exposure and lung function in a rural Chinese population. Results showed that factors such as sex, age, cooking oil fumes exposure, and occupational exposure were negatively correlated with lung function, while educational level, economic status, tea consumption, and alcohol consumption were positively correlated. Additionally, long-term exposure to high concentrations of PM2.5 was associated with reduced lung function in rural areas in northwestern China.
Our aim was to clarify the main factors associated with lung function and to analyze the correlation between fine particulate matter (PM2.5) and lung function in a rural Chinese population. We analyzed data of 5195 participants in the China Northwest Natural Population Cohort: Ningxia Project who were >= 30 years old. They were recruited from 2018 to 2019, underwent spirometry during the physical examination, and completed a self-report questionnaire. A satellite-based spatiotemporal model was used to estimate the 2-year average PM2.5 exposure based on participants' home addresses. A generalized linear mixed model was used to test the relationship between PM2.5 concentration and lung function. Sex, age, exposure to cooking oil fumes, and occupational exposure were negatively correlated (P < 0.05) with forced vital capacity (FVC) and forced expiratory volume in 1 s (FEV1). Educational status, economic level, tea consumption, and alcohol consumption were positively correlated (P < 0.05) with FVC and FEV1. The adjusted results of each model revealed that FVC and FEV1 decreased with increased exposure to PM2.5. There was a strong negative correlation between a PM2.5 concentration of 35.66 mu g/m(3) and FVC, FEV1, and FEV1/FVC, with unadjusted hazard ratios of - 0.06 (95% confidence interval, - 0.10 to - 0.01), - 0.13 (- 0.17 to - 0.10), and - 22.10 (- 24.62 to - 19.26), respectively. In conclusion, long-term exposure to high concentrations of ambient PM2.5 is related to reduce lung function among people in rural areas in northwestern China.
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