4.7 Article

Urinary bisphenol levels in plastic industry workers

期刊

ENVIRONMENTAL RESEARCH
卷 202, 期 -, 页码 -

出版社

ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.envres.2021.111666

关键词

Bisphenol A; Analogs; Occupational exposure; Urine; Men's reproductive health; Prevention

资金

  1. FCT/MCTES
  2. AgriFood XXI RDI project [NORTE-01-0145-FEDER-000041]
  3. European Regional Development Fund (ERDF) through NORTH 2020 (Northern Regional Operational Program 2014/2020)
  4. FCT [IF/01616/2015]
  5. [UIDB 50006/2020]
  6. Fundação para a Ciência e a Tecnologia [UIDB/50006/2020] Funding Source: FCT

向作者/读者索取更多资源

BPA and its analogs were found in stable levels in the urine of workers in the plastic industry, with BPA being the main component; the study found significant associations between BPA urinary levels and age, occupational exposure levels, and years of work experience.
Bisphenol A (BPA) is a known endocrine disruptor compound that is widely applied as a monomer base in polycarbonate plastics and as a binding agent in several epoxy resins. Plastic industry workers have usually heavier and prolonged exposures to BPA. Hence, the present work aims to assess the levels of BPA and their analogs (S, F, B, AF, Z, E, and AP) in 170 urine samples from a cross-sectional study of workers from a plastic industry located in north Constantine (Algeria). This work was complemented with a questionnaire about sexual functions and evaluation of sexual hormone levels. The results showed a stable presence of BPA (average of 3.24 mu g/L), accounting for more than 90% of the total BPs. Of the remaining BP analogs, only trace amounts of BPB were detected in three samples (average of 2.73 mu g/L). Significant associations with BPA urinary levels were noted with age (p = 0.006), occupational level of exposure (p = 0.023), and years of experience (p = 0.001).

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