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NATURE REVIEWS CANCER (2007)
The Wip1 phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop
Xiongbin Lu et al.
CANCER CELL (2007)
Regulation of p27Kip1 by miRNA 221/222 in Glioblastoma
Jana K. Gillies et al.
CELL CYCLE (2007)
p53-mediated activation of miRNA34 candidate tumor-suppressor genes
Guido T. Bommer et al.
CURRENT BIOLOGY (2007)
Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis
Tsung-Cheng Chang et al.
MOLECULAR CELL (2007)
Apoptosis: A review of programmed cell death
Susan Elmore
TOXICOLOGIC PATHOLOGY (2007)
Ser46 phosphorylation regulates p53-dependent apoptosis and replicative senescence
Lijin Feng et al.
CELL CYCLE (2006)
Wip1 phosphatase modulates ATM-dependent signaling pathways
Sathyavageeswaran Shreeram et al.
MOLECULAR CELL (2006)
Cells die with increased cytosolic ATP during apoptosis: a bioluminescence study with intracellular luciferase
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CELL DEATH AND DIFFERENTIATION (2005)
miR-15 and miR-16 induce apoptosis by targeting BCL2
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Phosphorylation of human p53 at serine 46 determines promoter selection and whether apoptosis is attenuated or amplified
LD Mayo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Combinatorial microRNA target predictions
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NATURE GENETICS (2005)
SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1
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JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
BP Lewis et al.
CELL (2005)
ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation
T Stiff et al.
CANCER RESEARCH (2004)
Mismatch repair and DNA damage signalling
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DNA REPAIR (2004)
Processing of primary microRNAs by the Microprocessor complex
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NATURE (2004)
Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair
JR Zhang et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
MicroRNA genes are transcribed by RNA polymerase II
Y Lee et al.
EMBO JOURNAL (2004)
TRAIL and apoptosis induction by TNF-family death receptors
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ONCOGENE (2003)
Requirement of the MRN complex for ATM activation by DNA damage
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EMBO JOURNAL (2003)
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
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SCIENCE (2003)
The cell cycle: a review of regulation, deregulation and therapeutic targets in cancer
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CELL PROLIFERATION (2003)
Decisions on life and death: FOXO Forkhead transcription factors are in command when PKB/Akt is off duty
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JOURNAL OF LEUKOCYTE BIOLOGY (2003)
Chk1 and Chk2 kinases in checkpoint control and cancer
J Bartek et al.
CANCER CELL (2003)
p53 binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice
IM Ward et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
ATM mediates phosphorylation at multiple p53 sites, including Ser46, in response to ionizing radiation
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JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin
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GENES & DEVELOPMENT (2002)
Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis
G D'Orazi et al.
NATURE CELL BIOLOGY (2002)
Mammalian G1- and S-phase checkpoints in response to DNA damage
J Bartek et al.
CURRENT OPINION IN CELL BIOLOGY (2001)
DNA damage-induced phosphorylation of p53 at serine 20 correlates with p21 and Mdm-2 induction in vivo
JR Jabbur et al.
ONCOGENE (2000)
Role of the p53-homologue p73 in EZF1-induced apoptosis
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NATURE GENETICS (2000)
Generation of oscillations by the p53-Mdm2 feedback loop: A theoretical and experimental study
RL Bar-Or et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
p53AlP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53
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CELL (2000)
DNA damage-induced activation of p53 by the checkpoint kinase Chk2
A Hirao et al.
SCIENCE (2000)
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