4.5 Article

Women with type 1 diabetes exhibit a progressive increase in gut Saccharomyces cerevisiae in pregnancy associated with evidence of gut inflammation

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Article Microbiology

Type 1 diabetes in pregnancy is associated with distinct changes in the composition and function of the gut microbiome

Alexandra J. Roth-Schulze et al.

Summary: This study found that pregnant women with T1D experienced significant changes in their gut microbiome towards a more pro-inflammatory state, associated with evidence of intestinal inflammation and epithelial damage. These changes could contribute to the increased risk of pregnancy complications in women with T1D and may be modifiable through dietary means.

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