4.4 Article

Brodalumab Is Associated with High Rates of Complete Clearance and Quality of Life Improvement: A Subgroup Analysis of Patients with Psoriasis and Concomitant Psoriatic Arthritis

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Dermatology

Complete clearance and psoriasis area and severity index response for brodalumab and ustekinumab in AMAGINE-2 and-3

R. B. Warren et al.

Summary: Modern biologics can achieve complete skin clearance in 30-45% of psoriasis patients. This study compared the effectiveness of brodalumab and ustekinumab in achieving PASI 90 and 100 responses, finding that brodalumab resulted in significantly higher levels of skin clearance, longer sustained response, and greater cumulative treatment benefit compared to ustekinumab. Additionally, there was a significant positive association between PASI response level and health-related quality of life.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (2021)

Review Medicine, General & Internal

Therapeutics targeting the IL-23 and IL-17 pathway in psoriasis

Kamran Ghoreschi et al.

Summary: Psoriasis is a chronic inflammatory disease affecting 2-3% of the global population, characterized by sharply demarcated erythematous and scaly skin lesions. The disease results from hyperproliferation and disturbed differentiation of epidermal keratinocytes provoked by immune mediators of the IL-23 and IL-17 pathway. Therapeutics targeting IL-23, IL-17, and IL-17RA have shown excellent efficacy in treating psoriasis.

LANCET (2021)

Article Rheumatology

Brodalumab in psoriatic arthritis: results from the randomised phase III AMVISION-1 and AMVISION-2 trials

Philip J. Mease et al.

Summary: The study demonstrated that brodalumab significantly improved symptoms and was well tolerated in patients with PsA compared to placebo.

ANNALS OF THE RHEUMATIC DISEASES (2021)

Review Rheumatology

Cardiometabolic comorbidities in RA and PsA: lessons learned and future directions

Lyn D. Ferguson et al.

NATURE REVIEWS RHEUMATOLOGY (2019)

Article Medicine, General & Internal

Psoriatic arthritis - new perspectives

Przemyslaw Krakowski et al.

ARCHIVES OF MEDICAL SCIENCE (2019)

Review Pharmacology & Pharmacy

Secukinumab: a review of the anti-IL-17A biologic for the treatment of psoriasis

Jillian Frieder et al.

THERAPEUTIC ADVANCES IN CHRONIC DISEASE (2018)

Review Immunology

Quality of life in psoriatic arthritis

Tania Gudu et al.

EXPERT REVIEW OF CLINICAL IMMUNOLOGY (2018)

Review Allergy

Clinical Features of Psoriatic Arthritis: a Comprehensive Review of Unmet Clinical Needs

Angela McArdle et al.

CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY (2018)

Review Rheumatology

Current concepts and unmet needs in psoriatic arthritis

Farrouq Mahmood et al.

CLINICAL RHEUMATOLOGY (2018)

Review Dermatology

Ixekizumab: A Review in Moderate to Severe Plaque Psoriasis

Yahiya Y. Syed

AMERICAN JOURNAL OF CLINICAL DERMATOLOGY (2017)

Article Medicine, General & Internal

Phase 3 Studies Comparing Brodalumab with Ustekinumab in Psoriasis

M. Lebwohl et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Review Dermatology

Early intervention in psoriasis and immune-mediated inflammatory diseases: A hypothesis paper

G. Girolomoni et al.

JOURNAL OF DERMATOLOGICAL TREATMENT (2015)

Article Dermatology

Patient-reported outcomes for psoriasis patients with clear versus almost clear skin in the clinical setting

Junko Takeshita et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2014)

Article Medicine, General & Internal

Brodalumab, an Anti-IL17RA Monoclonal Antibody, in Psoriatic Arthritis

Philip J. Mease et al.

NEW ENGLAND JOURNAL OF MEDICINE (2014)

Review Dermatology

Psoriasis and systemic inflammation: underdiagnosed enthesopathy

G. Girolomoni et al.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (2009)

Article Rheumatology

Psoriatic arthritis: epidemiology, clinical features, course, and outcome

DD Gladman et al.

ANNALS OF THE RHEUMATIC DISEASES (2005)