Cannabinoids interaction with transient receptor potential family and implications in the treatment of rosacea

With the recent interest in medical marijuana, research into cannabinoids is regaining wider attention. Cannabinoids are collectively a group of active compounds that can be produced by animals (endocannabinoids), plants (phytocannabinoids), or synthetically. By acting on a number of different receptors like cannabinoids receptors and transient receptor potential ion channel family, cannabinoids are known to modulate cutaneous inflammation, pain, and itch. Rosacea is a highly prevalent disease and can be associated with a significant degree of morbidity associated with its symptom. Transient receptor potential ion channels are known to be triggered in rosacea and may underlie a portion of rosacea's pathophysiology. This article aims to detail the transient receptor potential channel pathways in rosacea and the known effects of cannabinoids on these pathways and further discussing the potential role of cannabinoids in treating rosacea.

Automated summary

With the recent interest in medical marijuana, research into cannabinoids is regaining wider attention. Cannabinoids are known to modulate cutaneous inflammation, pain, and itch by acting on different receptors. Rosacea may be associated with transient receptor potential ion channels, and cannabinoids may play a potential role in treating rosacea by affecting these pathways.